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Protein

Peptidyl-prolyl cis-trans isomerase

Gene

AFUA_3G07430

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, RotamaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Short name:
PPIaseUniRule annotation
Gene namesi
ORF Names:AFUA_3G07430Imported
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)Imported
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiFungiDB:Afu3g07430.

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: ASPGD
Complete GO annotation...

Pathology & Biotechi

Protein family/group databases

Allergomei2677. Asp f 27.
3118. Asp f 27.0101.

PTM / Processingi

Proteomic databases

PRIDEiQ4WWX5.

Structurei

3D structure databases

ProteinModelPortaliQ4WWX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 162PPIase cyclophilin-typeInterPro annotationAdd BLAST157

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.UniRule annotation
Contains 1 PPIase cyclophilin-type domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000065981.
InParanoidiQ4WWX5.
KOiK01802.
OMAiFICTVAC.
OrthoDBiEOG092C5DG5.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4WWX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVKTFFDIT IDGQPAGRIT FKLFDEVVPK TVENFRALCT GEKGFGYKGS
60 70 80 90 100
SFHRIIPQFM LQGGDFTKGN GTGGKSIYGD RFPDENFQLK HDKPGLLSMA
110 120 130 140 150
NAGKNTNGSQ FFITTVVTSW LDGAHVVFGE VEDGMDLVKK IESYGSASGT
160
PKKKITIADC GQL
Length:163
Mass (Da):17,741
Last modified:July 5, 2005 - v1
Checksum:i5DD8D60816F3E918
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000002 Genomic DNA. Translation: EAL92828.1.
RefSeqiXP_754866.1. XM_749773.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00005730; CADAFUAP00005730; CADAFUAG00005730.
GeneIDi3512319.
KEGGiafm:AFUA_3G07430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000002 Genomic DNA. Translation: EAL92828.1.
RefSeqiXP_754866.1. XM_749773.1.

3D structure databases

ProteinModelPortaliQ4WWX5.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei2677. Asp f 27.
3118. Asp f 27.0101.

Proteomic databases

PRIDEiQ4WWX5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00005730; CADAFUAP00005730; CADAFUAG00005730.
GeneIDi3512319.
KEGGiafm:AFUA_3G07430.

Organism-specific databases

EuPathDBiFungiDB:Afu3g07430.

Phylogenomic databases

HOGENOMiHOG000065981.
InParanoidiQ4WWX5.
KOiK01802.
OMAiFICTVAC.
OrthoDBiEOG092C5DG5.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4WWX5_ASPFU
AccessioniPrimary (citable) accession number: Q4WWX5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: October 5, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.