Q4WWN3 (Q4WWN3_ASPFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Histone-lysine N-methyltransferase (Ash1), putative EMBL EAL92920.1

Gene names

ORF Names:

AFUA_3G06480 EMBL EAL92920.1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) [Reference proteome] EMBL EAL92920.1

Taxonomic identifier

330879 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Neosartorya fumigata

Protein attributes

Sequence length	845 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL92920.1

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS001214
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 EMBL EAL92920.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4WWN3 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 9AE9288F9ACB1FCE	FASTA	845	93,647
	10 20 30 40 50 60 MGKRTRSSVA SPATPATLSD LQKHAHEHVD ETIGLEVPEQ LLTPENSRSE TSSNSENACP 70 80 90 100 110 120 EEKPTLRRTS TRVTRSSLRA SGTFESKPEE EDAILPSLSG EMDPTNSSGN LANDVTKLKR 130 140 150 160 170 180 SQSSHLRHSI AVMETAVWSE STLTRHIMEA EDHLLTPDTP VSNSSQEPQL DDLNSSLPQR 190 200 210 220 230 240 SLRKRVERAL TKEDSYNRKK DESAARVDGP QPRRSTRLSL LEKASDCVEK AGSVLGKRSK 250 260 270 280 290 300 DMMEKGQILD RRASLRPRSV VAPKEEPASL TSSEPSAVKK RRVSESDLPS KTKAIDESTA 310 320 330 340 350 360 QSDTAAKEPR FKRKRWLSHG LYTGQEYTTA RPSQNRNKNA KRRSQGVPSQ RRLLPMPMFA 370 380 390 400 410 420 GDRLLQLGRD FQLPFDIYSP LPPGQPKPDE WRKTNKNVFV GEAGSIWRAN KHMELSKCMC 430 440 450 460 470 480 TEETGCDENC QNRYMFYECD DGNCGLGPGC GNRSFEELKQ RTKAGGKYNI GVEVIKTADR 490 500 510 520 530 540 GYGVRSNRTF EPNQIIVEYT GEIITQAECE KRMRTIYKNN ECYYLMYFDQ NMIIDATRGS 550 560 570 580 590 600 IARFVNHSCE PNCRMEKWTV AGKPRMALFA GDHGIMTGEE LTYDYNFDPY SQKNVQQCRC 610 620 630 640 650 660 GASNCRGILG PRPREKDQRS KESKIISQKN TSASKKSTTA KKVTGTKRKS GTVLDNSSSR 670 680 690 700 710 720 LNKKRKVLAP KSIAKQVKKV VSRVPATISK SANSRKKRTG KVQTEVSKTT AKKPQSSRSK 730 740 750 760 770 780 SQAKGKEAKP KSSVRLPKVK TAKTKVKAAI LPKKKSSKIT GKSPSKPKVS PASSSTLSRP 790 800 810 820 830 840 SAKAKEKILR VAKGANARKQ TTKGKTAGTK SPCKNPTSNS IKKRPGAASS TKRTKGASVE MVHST

References

[1]

"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W. Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAHF01000002 Genomic DNA. Translation: EAL92920.1.
RefSeq	XP_754958.1. XM_749865.1.
3D structure databases
ProteinModelPortal	Q4WWN3.
ModBase	Search...
Protein-protein interaction databases
STRING	5085.CADAFUAP00005795.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADAFUAT00005795; CADAFUAP00005795; CADAFUAG00005795.
GeneID	3512595.
KEGG	afm:AFUA_3G06480.
Phylogenomic databases
HOGENOM	HOG000194167.
KO	K06101.
OMA	GSIWRAN.
OrthoDB	EOG4FR41F.
Family and domain databases
InterPro	IPR006560. AWS. IPR003616. Post-SET_dom. IPR001214. SET_dom. [Graphical view]
Pfam	PF00856. SET. 1 hit. [Graphical view]
SMART	SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS51215. AWS. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4WWN3_ASPFU

Accession

Primary (citable) accession number: Q4WWN3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)