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Q4WW81 (Q4WW81_ASPFU) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL91145.1

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region37 – 404Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Region85 – 884Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Region138 – 1414Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Region168 – 1714N-acetyl-D-glucosamine binding PDB 4AHA
Region189 – 1924Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Region242 – 2454Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Region296 – 2994Fucose binding PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA

Sites

Binding site251Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site441Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site731Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site881Galactose
Binding site881N-acetyl-D-glucosamine PDB 4AH5
Binding site941Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site981Fucose; via amide nitrogen PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site1261Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site1261Galactose PDB 4AH5
Binding site1421Galactose PDB 4AH5
Binding site1461Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site1501Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site1771Fucose PDB 4AGT PDB 4AH4 PDB 4AHA
Binding site1771N-acetyl-D-glucosamine PDB 4AHA
Binding site1931N-acetyl-D-glucosamine PDB 4AHA
Binding site1981Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site2301Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site2821Fucose PDB 4AGT PDB 4AH4 PDB 4AH5 PDB 4AHA
Binding site3031Fucose PDB 4AH5

Amino acid modifications

Modified residue2441Cysteine sulfinic acid (-SO2H)

Sequences

Sequence LengthMass (Da)Tools
Q4WW81 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 22E0C1479074D154

FASTA31534,661
        10         20         30         40         50         60 
MSTPGAQQVL FRTGIAAVNL TNHLRVYFQD VYGSIRESLY EGSWANGTEK NVIGNAKLGS 

        70         80         90        100        110        120 
PVAATSKELK HIRVYTLTEG NTLQEFAYDS GTGWYNGGLG GAKFQVAPYS RIAAVFLAGT 

       130        140        150        160        170        180 
DALQLRIYAQ KPDNTIQEYM WNGDGWKEGT NLGGALPGTG IGATSFRYTD YNGPSIRIWF 

       190        200        210        220        230        240 
QTDDLKLVQR AYDPHKGWYP DLVTIFDRAP PRTAIAATSF GAGNSSIYMR IYFVNSDNTI 

       250        260        270        280        290        300 
WQVCWDHGKG YHDKGTITPV IQGSEVAIIS WGSFANNGPD LRLYFQNGTY ISAVSEWVWN 

       310 
RAHGSQLGRS ALPPA 

« Hide

References

« Hide 'large scale' references
[1]"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. expand/collapse author list , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.
Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.
[2]"Crystal Structure of Aspergillus Fumigatus Fucose- Specific Lectin."
Houser J., Komarek J., Kostlanova N., Lahmann M., Cioci G., Varrot A., Imberty A., Wimmerova M.
Submitted (JAN-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH FUCOSE.
[3]"Crystal Structure of Aspergillus Fumigatus Fucose- Specific Lectin."
Houser J., Komarek J., Kostlanova N., Lahmann M., Cioci G., Varrot A., Imberty A., Wimmerova M.
Submitted (FEB-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) IN COMPLEX WITH FUCOSE; GALACTOSE AND N-ACETYL-D-GLUCOSAMINE.
[4]"Crystal Structure of Aspergillus Fumigatus Fucose-Specific Lectin."
Houser J., Komarek J., Kostlanova N., Lahmann M., Cioci G., Varrot A., Imberty A., Wimmerova M.
Submitted (FEB-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) IN COMPLEX WITH FUCOSE AND N-ACETYL-D-GLUCOSAMINE.
[5]"Crystal Structure of Fucose Binding Lectin from Aspergillus."
Houser J., Komarek J., Kostlanova N., Lahmann M., Cioci G., Varrot A., Imberty A., Wimmerova M.
Submitted (FEB-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) IN COMPLEX WITH FUCOSE AND GALACTOSE.
[6]"Structure of Aspergillus Fumigatus Fucose-Specific Lectin."
Houser J., Komarek J., Kostlanova N., Lahmann M., Cioci G., Varrot A., Imberty A., Wimmerova M.
Submitted (FEB-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
[7]"A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity."
Houser J., Komarek J., Kostlanova N., Cioci G., Varrot A., Kerr S.C., Lahmann M., Balloy V., Fahy J.V., Chignard M., Imberty A., Wimmerova M.
PLoS ONE 8:e83077-e83077(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAHF01000003 Genomic DNA. Translation: EAL91145.1.
RefSeqXP_753183.1. XM_748090.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4AGIX-ray1.60A/B/C/D1-315[»]
4AGTX-ray2.00A/B1-315[»]
4AH4X-ray1.75A/B1-315[»]
4AH5X-ray1.99A/B1-315[»]
4AHAX-ray2.20A/B1-315[»]
4AHBX-ray1.75A/B/C/D1-315[»]
ProteinModelPortalQ4WW81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5085.CADAFUAP00006809.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFUAT00006809; CADAFUAP00006809; CADAFUAG00006809.
GeneID3511258.
KEGGafm:AFUA_5G14740.

Phylogenomic databases

HOGENOMHOG000217480.
OMAYGSIRES.
OrthoDBEOG78PVKS.

Family and domain databases

InterProIPR012475. Fungal_lectin.
[Graphical view]
PfamPF07938. Fungal_lectin. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4WW81_ASPFU
AccessionPrimary (citable) accession number: Q4WW81
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: March 19, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)