Q4WTV8 (Q4WTV8_ASPFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase HemA EMBL EAL91968.1
EC=2.3.1.37 EMBL EAL91968.1

Gene names

ORF Names:

AFUA_5G06270 EMBL EAL91968.1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) EMBL EAL91968.1

Taxonomic identifier

330879 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	640 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Molecular function	Acyltransferase EMBL EAL91968.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4WTV8 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 1AD6A132E2BB657F	FASTA	640	68,857
	10 20 30 40 50 60 MESLLQQSRA MCPFLKRTSP TALRTLATAT RPSMSPGGGT MSNLQVIARR CPVMSKALAV 70 80 90 100 110 120 QSARMAGAKR FTSTAAGVPG MSSKHFRPAQ TRRALHSTGG NGANLSPDLY KNTDRLQPTF 130 140 150 160 170 180 GTGKGKTPRA TSPSTVAGPR PEVPAPAPFD YNAFYLGELE KKHKDKSYRY FNNINRLAKE 190 200 210 220 230 240 FPRAHTASME ERVTVWCSND YLGMGRNPEV LATMHETLDT YGAGAGGTRN ISGHNKHAVA 250 260 270 280 290 300 LENTLANLHG KEAALVFSSC YVANDATLAT LGSKMPDCVI LSDSLNHASM IQGIRHSGAK 310 320 330 340 350 360 KMVFKHNDLV DLEQKLASLP LHVPKIIAFE SVYSMCGSIA PIEAICDLAD KYGAITFLDE 370 380 390 400 410 420 VHAVGMYGPH GAGVAEHLDY EIYASQDTPN PRSTKGTVMD RVDIITGTLG KAYGCVGGYI 430 440 450 460 470 480 AGSAAMVDTI RSLAPGFIFT TSLPPATMAG ANTAILYQAR HKGDRVLQQL HTRAVKKALK 490 500 510 520 530 540 ELDIPVIPNP SHIVPLLVGD AELAKKASDK LLEEHGIYVQ AINYPTVPRG EERLRITPTP 550 560 570 580 590 600 GHVKEHRDHL VHAVQAVWND LGIKRTSDWA AQGGFVGVGV EGAEEQNQPI WKDAQLGLVE 610 620 630 640 YESLEQAVER EFQQAPRMQT ATPIHPAAAP AASIPVGVAA

References

[1]

"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W. Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100 and ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAHF01000003 Genomic DNA. Translation: EAL91968.1.
RefSeq	XP_754006.1. XM_748913.1.
3D structure databases
ProteinModelPortal	Q4WTV8.
SMR	Q4WTV8. Positions 150-558.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4WTV8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADAFUAT00006263; CADAFUAP00006263; CADAFUAG00006263.
GeneID	3511542.
KEGG	afm:AFUA_5G06270.
Phylogenomic databases
eggNOG	fuNOG07159.
GeneTree	EFGT00050000002649.
HOGENOM	HBG649839.
OMA	MARIDIL.
OrthoDB	EOG412QDQ.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4WTV8_ASPFU

Accession

Primary (citable) accession number: Q4WTV8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)