Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q4WTM8 (Q4WTM8_ASPFU) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Porphobilinogen synthase, putative EMBL EAL90204.1
EC=4.2.1.24 EMBL EAL90204.1
Gene names
ORF Names:AFUA_1G08760 EMBL EAL90204.1
OrganismNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) EMBL EAL90204.1
Taxonomic identifier330879 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2451Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2981Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1681Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1701Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1781Zinc; catalytic By similarity PIRSR PIRSR001415-3
Binding site2551Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2671Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site3251Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3641Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
Q4WTM8 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: DFDEED129A45C12D

FASTA37340,651
        10         20         30         40         50         60 
MSFSNLVSDL AFRDAYDDRS SQISHSRSQA TARSYTSTAA TSVSISGDIS SQLHAGYSHP 

        70         80         90        100        110        120 
LTRSWQAERQ LTKEMLIYPL FITDNPDEET PIPSLPNQHR RGLNRLVPFL RPLVQKGLRS 

       130        140        150        160        170        180 
VILFGVPLHP TAKDALGTAA DDPSGPVIQA IRLLRSRFPN LYIVTDVCLC EYTSHGHCGI 

       190        200        210        220        230        240 
LREDGTLDNA QSVDRISDVA LAYATAGAHC VAPSDMNDGR VRAIKLKLIE AGLAHRVLLM 

       250        260        270        280        290        300 
SYSAKFSGCL YGPFRDAAGS CPSFGDRRCY QLPPGGRGLA RRAIQRDVGE GADIIMVKPA 

       310        320        330        340        350        360 
SSYLDIIRDA KELAKDMPIA AYQVSGEYAM IHAAAKAGVF DLKSMVFEST EGILRAGAGI 

       370 
IVSYFVPEFL DWL

« Hide

References

[1]"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. expand/collapse author list , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.
Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Af293 / CBS 101355 / FGSC A1100 and ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AAHF01000004 Genomic DNA. Translation: EAL90204.1.
RefSeqXP_752242.1. XM_747149.1.

3D structure databases

ProteinModelPortalQ4WTM8.
SMRQ4WTM8. Positions 48-373.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4WTM8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFUAT00007523; CADAFUAP00007523; CADAFUAG00007523.
GeneID3509771.
KEGGafm:AFUA_1G08760.

Phylogenomic databases

eggNOGfuNOG07497.
GeneTreeEFGT00050000001802.
HOGENOMHBG285270.
OMAGAHCVAP.
OrthoDBEOG454D75.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4WTM8_ASPFU
AccessionPrimary (citable) accession number: Q4WTM8
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info