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Protein

Pescadillo homolog

Gene

nop7

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.UniRule annotation

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Pescadillo homologUniRule annotation
Alternative name(s):
Nucleolar protein 7 homologUniRule annotation
Gene namesi
Name:nop7
ORF Names:AFUA_4G08190
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:Afu4g08190

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003704801 – 675Pescadillo homologAdd BLAST675

Interactioni

Subunit structurei

Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi5085.CADAFUBP00006354

Structurei

3D structure databases

ProteinModelPortaliQ4WP65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini352 – 471BRCTUniRule annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili551 – 675UniRule annotationAdd BLAST125

Sequence similaritiesi

Belongs to the pescadillo family.UniRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000006022
InParanoidiQ4WP65
KOiK14843
OMAiQWVFDCV
OrthoDBiEOG092C1M1S

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 2 hits
HAMAPiMF_03028 Pescadillo, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR010613 PES
PANTHERiPTHR12221 PTHR12221, 1 hit
PfamiView protein in Pfam
PF06732 Pescadillo_N, 1 hit
SUPFAMiSSF52113 SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit

Sequencei

Sequence statusi: Complete.

Q4WP65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIKKKGTS GQAKNYITRT QAVRKLQISL PDFRRLCIFK GIYPREPRNK
60 70 80 90 100
KKASKTSTPN TTFYYTKDIQ YLLHEPLLRK FREQKAVAKK IARSLGRGEV
110 120 130 140 150
GDAARLEKNH APKLTLDHVI KERYPTFIDA LRDLDDALSL LFLFANLPST
160 170 180 190 200
AHVPPKTIAL CQRLCHEFQH YLITTNSLRK SFLSIKGIYY QATIQGQDIL
210 220 230 240 250
WLVPYRFVQR VNGDVDYRIM ATFVDFYTTL LGFVNFRLYS SIGLRYPPKF
260 270 280 290 300
DTRSDENGAE LAAFTLEGRG VGDAPKAIEA GNTQATTSTN NKEVSKEIQA
310 320 330 340 350
KVDNVIKSAG LDEAKEEPAA ETTEESSETI DKFEPAAPEA DTLPQPDLSG
360 370 380 390 400
NEAGSLFAPF TFYISREAPR APLEFILRAF GCKRIGWDAV LGDGAFTHDE
410 420 430 440 450
TDTRITHQIV DRPQLPESSL PAIPAASKDG SDAVQKVKPG TRIPGRTYVQ
460 470 480 490 500
PQWVWDCINE GRLVRPDLYA PGATLPPHLS PWVKPSRGGY DPKASLAEQE
510 520 530 540 550
EEGEAELDED SDEEMEEATS DKKAEAKADV GSESEDEDES VDGGMDVAGT
560 570 580 590 600
DDDESESEDE EEDFDGFEEE AASESEDEEE AARTQHQKEL EAEAAGLPFS
610 620 630 640 650
SNGATSDGSK KKASQAKKIA AKKRKEEEEL ERQKMMMSRK KRKLLEKMIY
660 670
SNKKQSEEAA KLRSKRRKLE KGAAK
Length:675
Mass (Da):75,396
Last modified:July 5, 2005 - v1
Checksum:iCD8A83F699DA7E91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000005 Genomic DNA Translation: EAL89969.1
RefSeqiXP_752007.1, XM_746914.1

Genome annotation databases

EnsemblFungiiCADAFUAT00008029; CADAFUAP00008029; CADAFUAG00008029
GeneIDi3508981
KEGGiafm:AFUA_4G08190

Similar proteinsi

Entry informationi

Entry nameiPESC_ASPFU
AccessioniPrimary (citable) accession number: Q4WP65
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: July 5, 2005
Last modified: April 25, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health