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Protein

Pescadillo homolog

Gene

nop7

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Pescadillo homologUniRule annotation
Alternative name(s):
Nucleolar protein 7 homologUniRule annotation
Gene namesi
Name:nop7
ORF Names:AFUA_4G08190
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiFungiDB:Afu4g08190.

Subcellular locationi

  • Nucleusnucleolus UniRule annotation
  • Nucleusnucleoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 675675Pescadillo homologPRO_0000370480Add
BLAST

Interactioni

Subunit structurei

Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ4WP65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini352 – 471120BRCTUniRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili551 – 675125UniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pescadillo family.UniRule annotation
Contains 1 BRCT domain.UniRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000006022.
InParanoidiQ4WP65.
KOiK14843.
OMAiQYISRDY.
OrthoDBiEOG7HHX2C.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
HAMAPiMF_03028. Pescadillo.
InterProiIPR001357. BRCT_dom.
IPR010613. PES.
[Graphical view]
PfamiPF06732. Pescadillo_N. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4WP65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIKKKGTS GQAKNYITRT QAVRKLQISL PDFRRLCIFK GIYPREPRNK
60 70 80 90 100
KKASKTSTPN TTFYYTKDIQ YLLHEPLLRK FREQKAVAKK IARSLGRGEV
110 120 130 140 150
GDAARLEKNH APKLTLDHVI KERYPTFIDA LRDLDDALSL LFLFANLPST
160 170 180 190 200
AHVPPKTIAL CQRLCHEFQH YLITTNSLRK SFLSIKGIYY QATIQGQDIL
210 220 230 240 250
WLVPYRFVQR VNGDVDYRIM ATFVDFYTTL LGFVNFRLYS SIGLRYPPKF
260 270 280 290 300
DTRSDENGAE LAAFTLEGRG VGDAPKAIEA GNTQATTSTN NKEVSKEIQA
310 320 330 340 350
KVDNVIKSAG LDEAKEEPAA ETTEESSETI DKFEPAAPEA DTLPQPDLSG
360 370 380 390 400
NEAGSLFAPF TFYISREAPR APLEFILRAF GCKRIGWDAV LGDGAFTHDE
410 420 430 440 450
TDTRITHQIV DRPQLPESSL PAIPAASKDG SDAVQKVKPG TRIPGRTYVQ
460 470 480 490 500
PQWVWDCINE GRLVRPDLYA PGATLPPHLS PWVKPSRGGY DPKASLAEQE
510 520 530 540 550
EEGEAELDED SDEEMEEATS DKKAEAKADV GSESEDEDES VDGGMDVAGT
560 570 580 590 600
DDDESESEDE EEDFDGFEEE AASESEDEEE AARTQHQKEL EAEAAGLPFS
610 620 630 640 650
SNGATSDGSK KKASQAKKIA AKKRKEEEEL ERQKMMMSRK KRKLLEKMIY
660 670
SNKKQSEEAA KLRSKRRKLE KGAAK
Length:675
Mass (Da):75,396
Last modified:July 5, 2005 - v1
Checksum:iCD8A83F699DA7E91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000005 Genomic DNA. Translation: EAL89969.1.
RefSeqiXP_752007.1. XM_746914.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00008029; CADAFUAP00008029; CADAFUAG00008029.
GeneIDi3508981.
KEGGiafm:AFUA_4G08190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000005 Genomic DNA. Translation: EAL89969.1.
RefSeqiXP_752007.1. XM_746914.1.

3D structure databases

ProteinModelPortaliQ4WP65.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00008029; CADAFUAP00008029; CADAFUAG00008029.
GeneIDi3508981.
KEGGiafm:AFUA_4G08190.

Organism-specific databases

EuPathDBiFungiDB:Afu4g08190.

Phylogenomic databases

HOGENOMiHOG000006022.
InParanoidiQ4WP65.
KOiK14843.
OMAiQYISRDY.
OrthoDBiEOG7HHX2C.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
HAMAPiMF_03028. Pescadillo.
InterProiIPR001357. BRCT_dom.
IPR010613. PES.
[Graphical view]
PfamiPF06732. Pescadillo_N. 1 hit.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
    Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.
    , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.
    Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Entry informationi

Entry nameiPESC_ASPFU
AccessioniPrimary (citable) accession number: Q4WP65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: July 5, 2005
Last modified: June 8, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.