Q4WNY2 (Q4WNY2_ASPFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cobalamin-independent methionine synthase MetH/D EMBL EAL90052.1
EC=2.1.1.14 EMBL EAL90052.1

Gene names

ORF Names:

AFUA_4G07360 EMBL EAL90052.1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) EMBL EAL90052.1

Taxonomic identifier

330879 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	774 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL90052.1

Ontologies

Keywords
Molecular function	Methyltransferase EMBL EAL90052.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4WNY2 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 2D7CCCFB4F4EC6BB	FASTA	774	86,895
	10 20 30 40 50 60 MVQSAVLGFP RMGKLRDLKK ATEAYWGGKI SRDELLSEGK RLRAEHWKIQ KDAGVDIIPS 70 80 90 100 110 120 NDFAFYDQVL DHIQLFGVVP ERYSKYNLDP LDEYFAMGRG LQKPASEGQP AIDVPSLEMV 130 140 150 160 170 180 KWFDSNYHYV KPTLQENQVF KLASNPKPVA QFLEAKEAGI ITRPVILGPV SFLTLAKADR 190 200 210 220 230 240 GQKIDPIDKI NDLVPVYVDL LAQLKAAGVE DVQIDEPVLV FDLPAKSKAA FKPVYEKIGA 250 260 270 280 290 300 LGDKAPRIVL ATYFGDIVHN IDVLPALHNL HGIHVDLVRN PEQLDAVIAA LGPKQVLSAG 310 320 330 340 350 360 VVDGRNIWKT NFKAAIEKVE HAIQKLGKDR VIVSTSSSLL HVPHTLESEK NLDPEVREWF 370 380 390 400 410 420 SFAVEKTHEV VVIAKAVTEG PAAVRDQLEA NAKSVQARAS SARTNDPKVK ERQAAVTEEM 430 440 450 460 470 480 HNRKSPFPVR LAEQSKSINL PLFPTTTIGS FPQTKEIRIQ RNKFTKGEIT AEEYEKFIEQ 490 500 510 520 530 540 EIAEVVKIQE ELDLDVLVHG EPERNDMVQY FGERLTGYVF TTHAWVQSYG SRCVRPPIIV 550 560 570 580 590 600 GDISRPAPMT VKESKYAVSI SKKPMKGMLT GPITCLRWSF PRDDVHQSVQ AQQLALALRD 610 620 630 640 650 660 EVIDLEAAGV KVIQVDEPAL REGLPLRAGK EREDYLTWAV RAFRLATSGV SDGTQIHSHF 670 680 690 700 710 720 CYSEFQDFFH AIAALDADVL SIENSKSDAK LLKVFVEEAY PRHIGPGVYD IHSPRVPSEQ 730 740 750 760 770 EIKDRIEEML PYLRPDQLWI NPDCGLKTRQ WPETKAALTN MVNAAKFYRQ KYTK

References

[1]

"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W. Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100 and ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAHF01000005 Genomic DNA. Translation: EAL90052.1.
RefSeq	XP_752090.1. XM_746997.1.
3D structure databases
ProteinModelPortal	Q4WNY2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4WNY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADAFUAT00007970; CADAFUAP00007970; CADAFUAG00007970.
GeneID	3509461.
KEGG	afm:AFUA_4G07360.
Phylogenomic databases
eggNOG	fuNOG04536.
GeneTree	EFGT00050000006054.
HOGENOM	HBG287495.
OMA	NIWANDF.
OrthoDB	EOG4FBN20.
Family and domain databases
HAMAP	MF_00172. Meth_synth. [Tree]
InterPro	IPR013215. Cbl-indep_Met_Synth_N. IPR006276. Cobalamin-indep_Met_synthase. IPR002629. Methionine_synth. [Graphical view]
KO	K00549.
Pfam	PF08267. Meth_synt_1. 1 hit. PF01717. Meth_synt_2. 1 hit. [Graphical view]
PIRSF	PIRSF000382. MeTrfase_B12_ind. 1 hit.
TIGRFAMs	TIGR01371. Met_syn_B12ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4WNY2_ASPFU

Accession

Primary (citable) accession number: Q4WNY2

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)