Q4WLH7 (Q4WLH7_ASPFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL EAL89187.1
EC=4.1.1.15 EMBL EAL89187.1

Gene names

ORF Names:

AFUA_6G13490 EMBL EAL89187.1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) [Reference proteome] EMBL EAL89187.1

Taxonomic identifier

330879 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Neosartorya fumigata

Protein attributes

Sequence length	515 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL89187.1

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL EAL89187.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4WLH7 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: D22C81062758BDC8	FASTA	515	58,918
	10 20 30 40 50 60 MVHLATVKRD SEDVEPLVKR VDSIELETTD DDGFYSTVYG TRFAAEQLPQ NEMPEKEMPR 70 80 90 100 110 120 EVAYRMIKDE LSLDGNPMLN LASFVTTYME EEAEKLMTDS FSKNFIDYEE YPQSAEIQNR 130 140 150 160 170 180 CVSMIARLFN APINSDDEHP VGTSTIGSSE AIMLGTLAMK RRWQNKRKAE GKDTTRPNII 190 200 210 220 230 240 MNSAVQVCWE KAARYFDVEE RYVYCTEDRY VIDPKQAVDM VDENTIGICA ILGTTYTGEY 250 260 270 280 290 300 EDVKAINDLL VERGLDIPIH VDAASGGFVV PFINPNLLWD FRLEKVVSIN VSGHKYGLVY 310 320 330 340 350 360 PGVGWVVWRS PEYLPKELIF NINYLGAEQA SFTLNFSKGA SQVIGQYYQM IRLGKRGYRS 370 380 390 400 410 420 IMVNITRIAD YLAQQLEELG FIIMSQRRGR GLPLVAFRLP SDRDEQFDEF ALAHQLRERG 430 440 450 460 470 480 WIVPAYTMAP HSNELKLMRV VVREDFSKNR CDALLTDIKL ALKTLSDMDK AMLEKYTLHV 490 500 510 RKHSVNSHKS KHNHSHYKNE KHSLQGKTGK THGVC

References

[1]

"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W. Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAHF01000006 Genomic DNA. Translation: EAL89187.1.
RefSeq	XP_751225.1. XM_746132.1.
3D structure databases
ProteinModelPortal	Q4WLH7.
ModBase	Search...
Protein-protein interaction databases
STRING	5085.CADAFUAP00002241.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADAFUAT00002241; CADAFUAP00002241; CADAFUAG00002241.
GeneID	3508538.
KEGG	afm:AFUA_6G13490.
Phylogenomic databases
HOGENOM	HOG000070228.
KO	K01580.
OMA	PMDKEHM.
OrthoDB	EOG47Q1F8.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4WLH7_ASPFU

Accession

Primary (citable) accession number: Q4WLH7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)