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Protein

Acetamidase regulatory protein

Gene

amdR

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Positively regulates the expression of genes involved in the catabolism of certain amides, omega amino acids, and lactams.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi26 – 59Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST34

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Acetamidase regulatory protein
Gene namesi
Name:amdR
ORF Names:AFUA_1G03860
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:Afu1g03860

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002331151 – 772Acetamidase regulatory proteinAdd BLAST772

Structurei

3D structure databases

ProteinModelPortaliQ4WK35
SMRiQ4WK35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000211811
InParanoidiQ4WK35
KOiK09244
OMAiCRIHEKK
OrthoDBiEOG092C0I2N

Family and domain databases

CDDicd00067 GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR007219 Transcription_factor_dom_fun
IPR001138 Zn2-C6_fun-type_DNA-bd
IPR036864 Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF04082 Fungal_trans, 1 hit
PF00172 Zn_clus, 1 hit
SMARTiView protein in SMART
SM00906 Fungal_trans, 1 hit
SM00066 GAL4, 1 hit
SUPFAMiSSF57701 SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463 ZN2_CY6_FUNGAL_1, 1 hit
PS50048 ZN2_CY6_FUNGAL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q4WK35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSTAQKNSL SPTGNGVTKR KSGSAACVHC HRRKVRCDAR IVGLPCSNCR
60 70 80 90 100
SSGKTDCRIH EKKKRLAVRS ILNPVPIRCR PPSTSEHVPE ASPPSTISEP
110 120 130 140 150
TAFTTAFRGV QPEAAAPPAS VAPNVQSKAQ HLHSNSYSQT SPQAQECHLP
160 170 180 190 200
PASDRFAEQD AHADFEKRLV KLIDDEEGSG PREIQRGVRA IYVGHELSNM
210 220 230 240 250
SFLIRQQRDK DDDVYHFAGS EIPRRQLKTG HDQLLVDALT LPEPALVDEL
260 270 280 290 300
VQAYFTHVNP GYPIVEEDQF MSQYRNRDPS DPPPILLLQA ILLVGCHVTH
310 320 330 340 350
PKEERDALKA IFFRRAKWLF DNRIERNRDT LVQAALLLTW HSDSPDDDVS
360 370 380 390 400
ANAHYWVGVA ARIATGLGMH RNPVSSRFAP RDRRMWRRLW YILVQLDVMV
410 420 430 440 450
SLSYGRPQAI NLEDSDVSPL TASDFEGCGA RVQTDYVIHF SELCTMISYI
460 470 480 490 500
VRERFGLRVS SERRKAALQE ADEALANWSL RLPDHLRLRA SDMDPWSAML
510 520 530 540 550
HLTYNNFLIL LHRPHPRASA YSDDYGPHDA EICSAAAGVI TSIFEELRLN
560 570 580 590 600
DRLKYLWYSG VHTLFTAMIQ VRVELRFSNP VLAINALRRF DSASCSLREL
610 620 630 640 650
AKYWSHATTI LRLFEDSKRL QKDLRLATSE RSRPFSSTQD QPQAQALDQN
660 670 680 690 700
KNQHQHSSAD APVQPPQPDR LLPSYDSPTP DSTSLPQTAV SPHQNLTFDS
710 720 730 740 750
WIPSTNLATV DPMDQPREFL DWRQLFSFTD PDQPVLPMSM DGLPELEDEW
760 770
RQIYWQETPM SDLLQDGGWM HG
Length:772
Mass (Da):87,414
Last modified:July 5, 2005 - v1
Checksum:i47421977B4717B42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000007 Genomic DNA Translation: EAL88097.1
RefSeqiXP_750135.1, XM_745042.1

Genome annotation databases

EnsemblFungiiCADAFUAT00008577; CADAFUAP00008577; CADAFUAG00008577
GeneIDi3507372
KEGGiafm:AFUA_1G03860

Similar proteinsi

Entry informationi

Entry nameiAMDR_ASPFU
AccessioniPrimary (citable) accession number: Q4WK35
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: July 5, 2005
Last modified: April 25, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health