Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable arabinogalactan endo-beta-1,4-galactanase A

Gene

galA

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.By similarity

Catalytic activityi

The enzyme specifically hydrolyzes (1->4)-beta-D-galactosidic linkages in type I arabinogalactans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei157Proton donorBy similarity1
Active sitei268NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable arabinogalactan endo-beta-1,4-galactanase A (EC:3.2.1.89)
Alternative name(s):
Endo-1,4-beta-galactanase A
Short name:
Galactanase A
Gene namesi
Name:galA
ORF Names:AFUA_1G06910
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiFungiDB:Afu1g06910.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000039494622 – 356Probable arabinogalactan endo-beta-1,4-galactanase AAdd BLAST335

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi133N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ4WJ80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 53 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000217077.
InParanoidiQ4WJ80.
KOiK01224.
OrthoDBiEOG092C2PF8.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR011683. Glyco_hydro_53.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF07745. Glyco_hydro_53. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q4WJ80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGKTVLLPL LVLLCHSLAS ASLVYRGADI SSLLIEEKAG IEYKNVNGQT
60 70 80 90 100
QPLENILKAN GVNSVRQRVW VNPSDGSYNL DYNVKLAKRV KAAGMSVYLD
110 120 130 140 150
LHFSDTWADP SHQTTPRGWS TNDIGTLTWQ VYNYTMEVCN TFASNGIDVS
160 170 180 190 200
IVAIGNEIRN GLLWPLGKPD NYANIANILH SAAFGVKDST LSPKPKIMIH
210 220 230 240 250
LDNGWDWSAQ KFFYNRVLSS GANLVKSDFD LIGVSYYPFY NPSATLSALT
260 270 280 290 300
TSLKNLRSTY GKDVLVVETD WPVSCPNPAY AFPSDLKDIP FSVAGQTTFV
310 320 330 340 350
QRVANIVAQT PGGIGLYYWE PAWVQNAALG SSCADNLMVD WSTRQARTSL

SVFATI
Length:356
Mass (Da):39,105
Last modified:June 15, 2010 - v2
Checksum:i810E74AD6F3BB001
GO

Sequence cautioni

The sequence EAL88402 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000007 Genomic DNA. Translation: EAL88402.1. Different initiation.
RefSeqiXP_750440.1. XM_745347.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00009093; CADAFUAP00009093; CADAFUAG00009093.
GeneIDi3507699.
KEGGiafm:AFUA_1G06910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000007 Genomic DNA. Translation: EAL88402.1. Different initiation.
RefSeqiXP_750440.1. XM_745347.1.

3D structure databases

ProteinModelPortaliQ4WJ80.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00009093; CADAFUAP00009093; CADAFUAG00009093.
GeneIDi3507699.
KEGGiafm:AFUA_1G06910.

Organism-specific databases

EuPathDBiFungiDB:Afu1g06910.

Phylogenomic databases

HOGENOMiHOG000217077.
InParanoidiQ4WJ80.
KOiK01224.
OrthoDBiEOG092C2PF8.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR011683. Glyco_hydro_53.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF07745. Glyco_hydro_53. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGANA_ASPFU
AccessioniPrimary (citable) accession number: Q4WJ80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 7, 2016
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.