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Protein

Phosphotransferase

Gene

AFUA_2G05910

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • fructokinase activity Source: ASPGD
  • glucokinase activity Source: ASPGD
  • glucose binding Source: InterPro

GO - Biological processi

  • carbohydrate phosphorylation Source: ASPGD
  • cellular glucose homeostasis Source: InterPro
  • glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
ORF Names:AFUA_2G05910Imported
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)Imported
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiFungiDB:Afu2g05910.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ4WHC3.

Structurei

3D structure databases

ProteinModelPortaliQ4WHC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 221Hexokinase_1InterPro annotationAdd BLAST195
Domaini227 – 467Hexokinase_2InterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ4WHC3.
KOiK00844.
OMAiDICQSKY.
OrthoDBiEOG092C2JW4.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4WHC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGIGPKRPP SRKGSMADVP QNLLQQIKDF EEMFTVDKAK LKQVVDHFVK
60 70 80 90 100
ELDKGLSVEG GNIPMNVTWV MGFPDGDEQG TFLALDMGGT NLRVCEITLT
110 120 130 140 150
EEKGGFDICQ SKYRMPEELK TGTAEELWEY IADCIQQFIE FHHGEEGLTS
160 170 180 190 200
LPLGFTFSYP ATQEYIDHGI LQRWTKGFDI DGVEGQDVVP PLEETLKRKG
210 220 230 240 250
LPIKVAALIN DTTGTLIASA YTDPEMKIGC IFGTGVNAAY MENVGSVPKL
260 270 280 290 300
AHMNLPPDMP VAINCEYGAF DNEHVVLPLT KYDHIIDRDS PRPGQQAFEK
310 320 330 340 350
MTAGLYLGEI FRLALIDLLD SRPGLIFQNQ DTSKLRKPYL LDASFLAAIE
360 370 380 390 400
EDPYENLQET QELFERELNI KPTLAELEMI RRLAELIGTR AARLSACGVA
410 420 430 440 450
AICKKKNIES CHVGADGSVF TKYPHFKARG AQALREILDW APNEKDKVTI
460 470 480 490
MAAEDGSGVG AALIAALTLK RVKAGNLAGI RNKDEMQKLL
Length:490
Mass (Da):54,209
Last modified:July 5, 2005 - v1
Checksum:i3FE75D900092404B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000008 Genomic DNA. Translation: EAL87682.1.
RefSeqiXP_749720.1. XM_744627.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00003481; CADAFUAP00003481; CADAFUAG00003481.
GeneIDi3506901.
KEGGiafm:AFUA_2G05910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000008 Genomic DNA. Translation: EAL87682.1.
RefSeqiXP_749720.1. XM_744627.1.

3D structure databases

ProteinModelPortaliQ4WHC3.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ4WHC3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00003481; CADAFUAP00003481; CADAFUAG00003481.
GeneIDi3506901.
KEGGiafm:AFUA_2G05910.

Organism-specific databases

EuPathDBiFungiDB:Afu2g05910.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ4WHC3.
KOiK00844.
OMAiDICQSKY.
OrthoDBiEOG092C2JW4.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4WHC3_ASPFU
AccessioniPrimary (citable) accession number: Q4WHC3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: October 5, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.