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Protein

Hexokinase

Gene

AFUA_6G03980

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:AFUA_6G03980Imported
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)Imported
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000002530 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiFungiDB:Afu6g03980.

Interactioni

Protein-protein interaction databases

STRINGi5085.CADAFUAP00000751.

Structurei

3D structure databases

ProteinModelPortaliQ4WD97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ4WD97.
KOiK00844.
OMAiECMENAR.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

Q4WD97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKGLRTQPD LLSGAPEKLV IALQGLEELF AADRFLLRKI TDHFVKEMEK
60 70 80 90 100
GLSAEGGDIP MNVTWIMGYP TGKEQGKFLI LDMGGTSLRV SQAQLLGSDR
110 120 130 140 150
DMESIQEKYS IPQSIKQGTA DDLWDFVADC VQKFLQSRLS ESERSKVLPL
160 170 180 190 200
AFTFSYPVIQ SSIKVGVLQC WTKDFCVSGV EGHDVVFQLE AAFERKKIPV
210 220 230 240 250
QVVALVNDTV GTLFAAAHRD QEVKIGSIAS TGCNAAYMEE VAAIPKIQSC
260 270 280 290 300
GLPSGALVAI NTEYGAFDKS RRILPRTRFD DEIDRTSAHP GQQLYEKMVS
310 320 330 340 350
GPYLGELLRL VMLELHEAKL LFVGQDVSCL RQPNALEVSL FPTLEEDISE
360 370 380 390 400
CMENARKCLW EKTGLDPAPH ELKACRYLAE LVGTRAARLY SCGIAAICKK
410 420 430 440 450
RNIERCHIGV DGSIFGHYQN YRKRAAQALR DIFAWPDDLE DPIVFGFYKD
460 470
GSGVGAALIA ALALERSDGT VLSRTE
Length:476
Mass (Da):52,637
Last modified:July 5, 2005 - v1
Checksum:iDE8B644C6F3C541C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000012 Genomic DNA. Translation: EAL85641.1.
RefSeqiXP_747679.1. XM_742586.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00000751; CADAFUAP00000751; CADAFUAG00000751.
GeneIDi3505347.
KEGGiafm:AFUA_6G03980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000012 Genomic DNA. Translation: EAL85641.1.
RefSeqiXP_747679.1. XM_742586.1.

3D structure databases

ProteinModelPortaliQ4WD97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5085.CADAFUAP00000751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00000751; CADAFUAP00000751; CADAFUAG00000751.
GeneIDi3505347.
KEGGiafm:AFUA_6G03980.

Organism-specific databases

EuPathDBiFungiDB:Afu6g03980.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ4WD97.
KOiK00844.
OMAiECMENAR.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus."
    Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.
    , Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H., Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B., Denning D.W.
    Nature 438:1151-1156(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100Imported.

Entry informationi

Entry nameiQ4WD97_ASPFU
AccessioniPrimary (citable) accession number: Q4WD97
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: May 27, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.