Q4WD72 (Q4WD72_ASPFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-methylcitrate dehydratase, putative EMBL EAL85666.1
EC=4.2.1.79 EMBL EAL85666.1

Gene names

ORF Names:

AFUA_6G03730 EMBL EAL85666.1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) EMBL EAL85666.1

Taxonomic identifier

330879 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	558 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL85666.1

Ontologies

Keywords
Molecular function	Lyase EMBL EAL85666.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	propionate catabolic process, 2-methylcitrate cycle Inferred from electronic annotation. Source: InterPro
Molecular function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: InterPro 2-methylcitrate dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4WD72 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: BDEC88EFD6486E2C	FASTA	558	62,105
	10 20 30 40 50 60 MSASCSALRR LTHRSPRTLP SRIVSVSRPS SRIVARNSFT KAVNPCAPRV SQFSTMTALQ 70 80 90 100 110 120 HGAPAAPTER NYDPEIKDMA DYVHNYSVNS DLAYDTARLV FLDTLGCGLE ALRFKECAKL 130 140 150 160 170 180 LGPVVEGTVV PNGTRVPGTP YQLDPVNGAF NIGAMIRWLD YNDCWLAAEW GHPSDNLGGI 190 200 210 220 230 240 LAVADWISRT NRAGGNLGNG KIVKVKEVLE AMIKAHEIQG VLALENSYNR VGLDHVVLVK 250 260 270 280 290 300 VATTAVVAKM LGLNEKQTAD AITQAWVDGQ SLRTYRHSPN TMSRKSWAAG DACQRAVNLV 310 320 330 340 350 360 LKVQKGEGGV PTVLSAPVWG FYDVLFKGNK FKFQRPYGSY VMENVLFKVS YPAEFHSQTA 370 380 390 400 410 420 IECAQIINRK LAAMGKSAKD IKEITNRTHE ACIRIIDKQF KAMDNFADRD HCVQYMVATM 430 440 450 460 470 480 LAFNRLTAED YADGSEAATS PLVEDLRKRI RCVEDPQFTR DYHDPAKRTI PNALTVTLND 490 500 510 520 530 540 GTVLEEVVVE APLGHRFRRE EAKPEILSKY KRHLEAHFDQ ARIDELLKIG LDRSSLENYD 550 VDKYVDLYVK DKMVVAAQ

References

[1]

"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. , Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W. Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100 and ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAHF01000012 Genomic DNA. Translation: EAL85666.1.
RefSeq	XP_747704.1. XM_742611.1.
3D structure databases
ProteinModelPortal	Q4WD72.
SMR	Q4WD72. Positions 72-549.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4WD72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADAFUAT00000455; CADAFUAP00000455; CADAFUAG00000455.
GeneID	3505070.
KEGG	afm:AFUA_6G03730.
Phylogenomic databases
eggNOG	fuNOG05414.
GeneTree	EFGT00070000008736.
HOGENOM	HBG298383.
OMA	CLMDTLG.
OrthoDB	EOG44XNR9.
Family and domain databases
InterPro	IPR012705. 2Me_IsoCit_deHydtase_PrpD. IPR005656. MmgE_PrpD. [Graphical view]
KO	K01720.
PANTHER	PTHR16943. MmgE_PrpD. 1 hit.
Pfam	PF03972. MmgE_PrpD. 1 hit. [Graphical view]
SUPFAM	SSF103378. MmgE_PrpD. 1 hit.
TIGRFAMs	TIGR02330. PrpD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4WD72_ASPFU

Accession

Primary (citable) accession number: Q4WD72

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)