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Protein

ABC transporter fmpD

Gene

fmpD

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

ABC transporter; part of the gene cluster that mediates the biosynthesis of fumipyrrole, a brown pigment that is involved in growth and conidiation (PubMed:25582336).1 Publication

Pathwayi: Secondary metabolite biosynthesis

This protein is involved in Secondary metabolite biosynthesis.1 Publication
View all proteins of this organism that are known to be involved in Secondary metabolite biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi413 – 420ATPPROSITE-ProRule annotation8
Nucleotide bindingi1078 – 1085ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter fmpD1 Publication
Alternative name(s):
Fumipyrrole biosynthesis protein D1 Publication
Gene namesi
Name:fmpD1 Publication
ORF Names:AFUA_6G03470
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiFungiDB:Afu6g03470.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei57 – 77HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei102 – 122HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei176 – 196HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei203 – 223HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei281 – 301HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei312 – 332HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei707 – 727HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei753 – 773HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei831 – 851HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei855 – 875HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei931 – 951HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei968 – 988HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004388721 – 1285ABC transporter fmpDAdd BLAST1285

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi467N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1037N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1138N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Expressioni

Inductioni

Expression is positively regulated by the fumipyrrole biosynthesis specific transcription factor fmpR (PubMed:25582336).1 Publication

Interactioni

Protein-protein interaction databases

STRINGi5085.CADAFUBP00009216.

Structurei

3D structure databases

ProteinModelPortaliQ4WD46.
SMRiQ4WD46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 343ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini380 – 622ABC transporter 1PROSITE-ProRule annotationAdd BLAST243
Domaini713 – 996ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST284
Domaini1043 – 1281ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ4WD46.
KOiK05658.
OMAiVMMGAMS.
OrthoDBiEOG092C06DT.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q4WD46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPQMVSQL DDARLDERQR AILDRQLHGL GGETKQRKNV FAYATVSDRI
60 70 80 90 100
VLSVSSICAV LAGALNPLVP VIYGLLVSVY DGFAAGTVSA SELRSKTATF
110 120 130 140 150
SLYYVYLSIG LFAFTYVATV GFYYTGERMA RALRTTYLAA ILRQNMAFFD
160 170 180 190 200
LLGPGEITSR IMSDMGTVQE AVTSKLAVML TAIATFCAAF VVAFIMYWKT
210 220 230 240 250
ALIISPFFVI MIVTETLGGA YMVRHHKRAM ELYSQAAGIA EEAIAAIKHV
260 270 280 290 300
TAFGIQTLLS QRYLSVLEQA AKADRKAENM VAGMIAWMNA MPNLIYALAF
310 320 330 340 350
WAGSIYLTRG QMSVAEVSAT TLAVTIGSFA IIRIAPSAQA LLSGIAITGE
360 370 380 390 400
ILKSIARRSP QDPLVKEGDE PSTVVGDIVL DRVGLIYPSR DDVDILQDVS
410 420 430 440 450
LRCAAMKKTA IVGSSGSGKS SILGLVERFY EPTSGTVLLD GRDIQSLNLR
460 470 480 490 500
WLRRQIALVD QMPVLFNATI LENILYGCSD MVSQWSESEQ LDRVVQASKK
510 520 530 540 550
ANAHDFISAL PDGYHTHVGE KGLQLSGGQR QRVAIARALI RDPKILLLDE
560 570 580 590 600
ATSALDSKSE AMVQEALDAA AEHRTTIIVA HRLSTIQNAD HIIVLDHGKV
610 620 630 640 650
VEEGTHHALV AQNGAYAALV QKQQIGDTHD HKAPDGARLS IEDDDDEDSR
660 670 680 690 700
YGGNTEYVDE KDIRTEEVAL SSAAHDEGTQ RDSLKLSALQ TIAFIARLSK
710 720 730 740 750
RDWKVLLFGL ANAILAGLTI PVQSVFFAKI LTVIGFPPPQ YPQLRSEVDF
760 770 780 790 800
WSGLYVMLTG TTFLFWMGVE IALSYATQKL ARRVREVCFR SILVQDMAFF
810 820 830 840 850
DVPGNSPSAL SSVLSKSTND LAGLGGPVMG GILTFLSTIL AGIVLALAIG
860 870 880 890 900
WKLALVCTAT IPIVVACGWL RLQVLSTFDS KVRQSGIESA AYAGELVRTV
910 920 930 940 950
RTVASLGLEE HALARYEGIL AKQAAKSLRS ILLASALYAA SASVVYLCAA
960 970 980 990 1000
LAFWYGGTLI ASHEYSTFQV YICFVSLISG SQIAGSIFTY APDASKAMHA
1010 1020 1030 1040 1050
SREIQDIMNL KPSINKVAPT GPPPAHEGTE KNQPQQNLSA CRVEFEHVSF
1060 1070 1080 1090 1100
TYPSRPTRRA LDNLHITVEP GQTLALVGQS GSGKSTCVSL LERFYDPDQG
1110 1120 1130 1140 1150
RILIDGQDIK LRDVDEYRRD ISLVSQETII FSGTIRDNIT VGLAGQEVSD
1160 1170 1180 1190 1200
DEILEACKQA NILEFVQSLP DGLSTLVGTG GSMLSGGQKQ RIAIARAFLR
1210 1220 1230 1240 1250
KPKILLLDEA TSALDSQSEA IVQEAMDAIR KDRTTIMVAH RLSTVQNADV
1260 1270 1280
ICVLQDGKLL EIGTHEQLLG KRGKYWEMVS MQSLH
Length:1,285
Mass (Da):139,635
Last modified:July 5, 2005 - v1
Checksum:i8F5B46138F8B610B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000012 Genomic DNA. Translation: EAL85692.1.
RefSeqiXP_747730.1. XM_742637.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00000462; CADAFUAP00000462; CADAFUAG00000462.
GeneIDi3505177.
KEGGiafm:AFUA_6G03470.

Similar proteinsi

Entry informationi

Entry nameiFMPD_ASPFU
AccessioniPrimary (citable) accession number: Q4WD46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2017
Last sequence update: July 5, 2005
Last modified: July 5, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways