Unreviewed, UniProtKB/TrEMBL Q4W5N3 (Q4W5N3_HUMAN)

Names and origin

Protein names

Submitted name:
    C-terminal binding protein 1, isoform CRA_a EMBL EAW82599.1
Submitted name:
    Putative uncharacterized protein CTBP1 EMBL AAY40989.1

Gene names

Name:	CTBP1 EMBL AAY40989.1
ORF Names:	hCG_1981976 EMBL EAW82599.1

Organism

Homo sapiens (Human) EMBL AAY40989.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Ontologies

Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro negative regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara
Cellular component	transcription factor complex Inferred from electronic annotation. Source: Compara
Molecular function	NAD or NADH binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: Compara transcription factor binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4W5N3-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: F071DD30B385603F	FASTA	440	47,535
	10 20 30 40 50 60 MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ 70 80 90 100 110 120 EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV 130 140 150 160 170 180 PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII 190 200 210 220 230 240 GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN 250 260 270 280 290 300 EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS 310 320 330 340 350 360 QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT 370 380 390 400 410 420 HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA 430 440 PSPGQTVKPE ADRDHASDQL

References

[1]	"The sequence of Homo sapiens BAC clone RP11-20I20." Dixon R., Cotton M., McLellan M. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Waterston R.H. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Waterston R. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Wilson R.K. Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC092535 Genomic DNA. Translation: AAY40989.1. CH471131 Genomic DNA. Translation: EAW82599.1.
IPI	IPI00012835.
RefSeq	NP_001319.1.
UniGene	Hs.208597 Hs.594321
3D structure databases
SMR	Q4W5N3. Positions 28-352.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4W5N3.
Proteomic databases
PRIDE	Q4W5N3.
Genome annotation databases
Ensembl	ENST00000290921; ENSP00000290921; ENSG00000159692; Homo sapiens. [Genome view]
GeneID	1487.
NMPDR	fig|9606.3.peg.23792.
Organism-specific databases
CTD	1487.
HGNC	HGNC:2494. CTBP1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q4W5N3.
OMA	PIMNGPM.
PhylomeDB	Q4W5N3.
Gene expression databases
ArrayExpress	Q4W5N3.
Bgee	Q4W5N3.
Family and domain databases
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	6105.

Entry information

Entry name

Q4W5N3_HUMAN

Accession

Primary (citable) accession number: Q4W5N3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	February 9, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.