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Q4W5L2

- Q4W5L2_HUMAN

UniProt

Q4W5L2 - Q4W5L2_HUMAN

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Protein
Submitted name: Putative uncharacterized protein SNCA
Gene
SNCA
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. arachidonic acid binding Source: Ensembl
  2. phospholipid binding Source: Ensembl

GO - Biological processi

  1. adult locomotory behavior Source: Ensembl
  2. aging Source: Ensembl
  3. behavioral response to cocaine Source: Ensembl
  4. cellular response to fibroblast growth factor stimulus Source: Ensembl
  5. cellular response to oxidative stress Source: Ensembl
  6. dopamine biosynthetic process Source: Ensembl
  7. fatty acid metabolic process Source: Ensembl
  8. long-term synaptic potentiation Source: Ensembl
  9. microglial cell activation Source: Ensembl
  10. mitochondrial ATP synthesis coupled electron transport Source: Ensembl
  11. mitochondrial membrane organization Source: Ensembl
  12. negative regulation of dopamine metabolic process Source: Ensembl
  13. negative regulation of neuron apoptotic process Source: Ensembl
  14. negative regulation of protein phosphorylation Source: Ensembl
  15. neutral lipid metabolic process Source: Ensembl
  16. phospholipid metabolic process Source: Ensembl
  17. positive regulation of neurotransmitter secretion Source: Ensembl
  18. positive regulation of peptidyl-serine phosphorylation Source: Ensembl
  19. regulation of acyl-CoA biosynthetic process Source: Ensembl
  20. regulation of dopamine secretion Source: Ensembl
  21. regulation of excitatory postsynaptic membrane potential Source: Ensembl
  22. regulation of glutamate secretion Source: Ensembl
  23. regulation of locomotion Source: Ensembl
  24. regulation of long-term neuronal synaptic plasticity Source: Ensembl
  25. regulation of macrophage activation Source: Ensembl
  26. response to drug Source: Ensembl
  27. synapse organization Source: Ensembl
  28. synaptic transmission, dopaminergic Source: Ensembl
  29. synaptic vesicle endocytosis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein SNCAImported
Gene namesi
Name:SNCAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: Ensembl
  2. cytoplasmic vesicle membrane Source: Ensembl
  3. cytoskeleton Source: Ensembl
  4. cytosol Source: Ensembl
  5. growth cone Source: Ensembl
  6. mitochondrion Source: Ensembl
  7. nuclear outer membrane Source: Ensembl
  8. plasma membrane Source: Ensembl
  9. ribosome Source: Ensembl
  10. rough endoplasmic reticulum Source: Ensembl
  11. synaptic vesicle Source: Ensembl
  12. terminal bouton Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ4W5L2.

Expressioni

Gene expression databases

ArrayExpressiQ4W5L2.
BgeeiQ4W5L2.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000008691.
HOVERGENiHBG000481.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Fragment.

Q4W5L2-1 [UniParc]FASTAAdd to Basket

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MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH    50
GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL 100
GK 102
Length:102
Mass (Da):10,190
Last modified:July 5, 2005 - v1
Checksum:i78D2159484F9250D
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei102 – 1021Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093759 Genomic DNA. Translation: AAY40956.1.
UniGeneiHs.21374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093759 Genomic DNA. Translation: AAY40956.1 .
UniGenei Hs.21374.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q4W5L2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000008691.
HOVERGENi HBG000481.

Miscellaneous databases

ChiTaRSi SNCA. human.

Gene expression databases

ArrayExpressi Q4W5L2.
Bgeei Q4W5L2.

Family and domain databases

Gene3Di 1.10.287.700. 1 hit.
InterProi IPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view ]
PANTHERi PTHR13820. PTHR13820. 1 hit.
Pfami PF01387. Synuclein. 1 hit.
[Graphical view ]
PRINTSi PR01212. ASYNUCLEIN.
PR01211. SYNUCLEIN.
ProtoNeti Search...

Publicationsi

  1. "The sequence of Homo sapiens BAC clone RP11-67M1."
    Meyer R., Mulvaney E.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Wilson R.K.
    Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ4W5L2_HUMAN
AccessioniPrimary (citable) accession number: Q4W5L2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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