Unreviewed, UniProtKB/TrEMBL Q4W5F3 (Q4W5F3_HUMAN)

Names and origin

Protein names

Submitted name:
    cDNA FLJ76062, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 29(ADAM29), transcript variant 1, mRNA EMBL BAF85099.1
Submitted name:
    ADAM metallopeptidase domain 29, isoform CRA_a EMBL EAX04727.1
    Putative uncharacterized protein ADAM29 EMBL AAY41055.1

Gene names

Name:	ADAM29 EMBL AAY41055.1
ORF Names:	hCG_1786734 EMBL EAX04727.1

Organism

Homo sapiens (Human) EMBL AAY41055.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	820 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 disintegrin domain. RuleBase RU004074V3 Spearmint SPM001762 Contains 1 peptidase M12B domain. RuleBase RU004141V0 Spearmint SPM001762

Ontologies

Keywords
Molecular function	Integrin
PTM	Disulfide bond Spearmint SPM001762
Gene Ontology (GO)
Biological process	integrin-mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4W5F3-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: AA2FB11342A884C9	FASTA	820	92,759
	10 20 30 40 50 60 MKMLLLLHCL GVFLSCSGHI QDEHPQYHSP PDVVIPVRIT GTTRGMTPPG WLSYILPFGG 70 80 90 100 110 120 QKHIIHIKVK KLLFSKHLPV FTYTDQGAIL EDQPFVQNNC YYHGYVEGDP ESLVSLSTCF 130 140 150 160 170 180 GGFQGILQIN DFAYEIKPLA FSTTFEHLVY KMDSEEKQFS TMRSGFMQNE ITCRMEFEEI 190 200 210 220 230 240 DNSTQKQSSY VGWWIHFRIV EIVVVIDNYL YIRYERNDSK LLEDLYVIVN IVDSILDVIG 250 260 270 280 290 300 VKVLLFGLEI WTNKNLIVVD DVRKSVHLYC KWKSENITPR MQHDTSHLFT TLGLRGLSGI 310 320 330 340 350 360 GAFRGMCTPH RSCAIVTFMN KTLGTFSIAV AHHLGHNLGM NHDEDTCRCS QPRCIMHEGN 370 380 390 400 410 420 PPITKFSNCS YGDFWEYTVE RTKCLLETVH TKDIFNVKRC GNGVVEEGEE CDCGPLKHCA 430 440 450 460 470 480 KDPCCLSNCT LTDGSTCAFG LCCKDCKFLP SGKVCRKEVN ECDLPEWCNG TSHKCPDDFY 490 500 510 520 530 540 VEDGIPCKER GYCYEKSCHD RNEQCRRIFG AGANTASETC YKELNTLGDR VGHCGIKNAT 550 560 570 580 590 600 YIKCNISDVQ CGRIQCENVT EIPNMSDHTT VHWARFNDIM CWSTDYHLGM KGPDIGEVKD 610 620 630 640 650 660 GTECGIDHIC IHRHCVHITI LNSNCSPAFC NKRGICNNKH HCHCNYLWDP PNCLIKGYGG 670 680 690 700 710 720 SVDSGPPPKR KKKKKFCYLC ILLLIVLFIL LCCLYRLCKK SKPIKKQQDV QTPSAKEEEK 730 740 750 760 770 780 IQRRPHELPP QSQPWVMPSQ SQPPVTPSQS HPQVMPSQSQ PPVTPSQSQP RVMPSQSQPP 790 800 810 820 VMPSQSHPQL TPSQSQPPVT PSQRQPQLMP SQSQPPVTPS

References

[1]	"The sequence of Homo sapiens BAC clone RP13-577H12." Meyer R., Dignan G., Wang C. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Waterston R.H. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Waterston R. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Wilson R.K. Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[6]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL BAF85099.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC105914 Genomic DNA. Translation: AAY41055.1. AK292410 mRNA. Translation: BAF85099.1. CH471056 Genomic DNA. Translation: EAX04727.1.
IPI	IPI00289829.
RefSeq	NP_001124175.1. NP_001124176.1. NP_001124177.1. NP_055084.3.
UniGene	Hs.126838
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q4W5F3.
Genome annotation databases
Ensembl	ENSG00000168594. Homo sapiens. [Contig view]
GeneID	11086.
KEGG	hsa:11086.
Organism-specific databases
HGNC	HGNC:207. ADAM29.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q4W5F3.
OMA	Q4W5F3. MPSQSQP.
Gene expression databases
ArrayExpress	Q4W5F3.
Bgee	Q4W5F3.
Family and domain databases
InterPro	IPR006586. ADAM_Cys-rich. IPR001762. Blood-coag_inhib_Disintegrin. IPR018358. Disintegrin_CS. IPR001590. Peptidase_M12B. IPR002870. Peptidase_M12B_N. [Graphical view]
Gene3D	G3DSA:4.10.70.10. Blood-coag_inhib_Disintegrin. 1 hit.
Pfam	PF08516. ADAM_CR. 1 hit. PF00200. Disintegrin. 1 hit. PF01562. Pep_M12B_propep. 1 hit. PF01421. Reprolysin. 1 hit. [Graphical view]
PRINTS	PR00289. DISINTEGRIN.
ProDom	PD000664. Disintegrin. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00608. ACR. 1 hit. SM00050. DISIN. 1 hit. [Graphical view]
PROSITE	PS50215. ADAM_MEPRO. 1 hit. PS00427. DISINTEGRIN_1. 1 hit. PS50214. DISINTEGRIN_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	42152.

Entry information

Entry name

Q4W5F3_HUMAN

Accession

Primary (citable) accession number: Q4W5F3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	May 5, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)