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Q4VX67

- S31A4_HUMAN

UniProt

Q4VX67 - S31A4_HUMAN

Protein

Spermatogenesis-associated protein 31A4

Gene

SPATA31A4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 2 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    May play a role in spermatogenesis.By similarity

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. spermatogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Differentiation, Spermatogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spermatogenesis-associated protein 31A4
    Alternative name(s):
    Protein FAM75A4
    Gene namesi
    Name:SPATA31A4
    Synonyms:FAM75A4
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:32004. SPATA31A4.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13471347Spermatogenesis-associated protein 31A4PRO_0000313019Add
    BLAST

    Proteomic databases

    PRIDEiQ4VX67.

    PTM databases

    PhosphoSiteiQ4VX67.

    Expressioni

    Gene expression databases

    BgeeiQ4VX67.
    GenevestigatoriQ4VX67.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4VX67.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei23 – 4321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi120 – 228109Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SPATA31 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000015250.
    HOVERGENiHBG107892.
    InParanoidiQ4VX67.
    PhylomeDBiQ4VX67.

    Family and domain databases

    InterProiIPR027970. DUF4599.
    [Graphical view]
    PfamiPF15371. DUF4599. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4VX67-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF VLLPYLSYFR     50
    CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ 100
    LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS 150
    PLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP 200
    PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVAFPLGTV 250
    PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 300
    HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF 350
    TNRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD 400
    PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM 450
    SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ 500
    AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR 550
    QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 600
    QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG 650
    ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE 700
    LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV 750
    RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL 800
    GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG 850
    AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 900
    GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSIQQSRS LGAQSSKAGE 950
    TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP 1000
    RKLCLMEEVV NEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV 1050
    SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRN PNCQGSCKSQ 1100
    RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL 1150
    LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSRVY 1200
    SSSAEAQGLM TAVGQMLDKK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH 1250
    RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ 1300
    WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI 1347
    Length:1,347
    Mass (Da):148,755
    Last modified:January 15, 2008 - v2
    Checksum:iDBAF3B1CA2D4C3EE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596385 Genomic DNA. Translation: CAI95396.1.
    UniGeneiHs.123004.
    Hs.645497.

    Polymorphism databases

    DMDMi166233527.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596385 Genomic DNA. Translation: CAI95396.1 .
    UniGenei Hs.123004.
    Hs.645497.

    3D structure databases

    ProteinModelPortali Q4VX67.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q4VX67.

    Polymorphism databases

    DMDMi 166233527.

    Proteomic databases

    PRIDEi Q4VX67.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    GeneCardsi GC09M041321.
    HGNCi HGNC:32004. SPATA31A4.
    neXtProti NX_Q4VX67.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000015250.
    HOVERGENi HBG107892.
    InParanoidi Q4VX67.
    PhylomeDBi Q4VX67.

    Miscellaneous databases

    PROi Q4VX67.

    Gene expression databases

    Bgeei Q4VX67.
    Genevestigatori Q4VX67.

    Family and domain databases

    InterProi IPR027970. DUF4599.
    [Graphical view ]
    Pfami PF15371. DUF4599. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiS31A4_HUMAN
    AccessioniPrimary (citable) accession number: Q4VX67
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 52 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3