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Q4VX67

- S31A4_HUMAN

UniProt

Q4VX67 - S31A4_HUMAN

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Protein

Spermatogenesis-associated protein 31A4

Gene
SPATA31A4, FAM75A4
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

May play a role in spermatogenesis By similarity.

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. spermatogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31A4
Alternative name(s):
Protein FAM75A4
Gene namesi
Synonyms:FAM75A4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:32004. SPATA31A4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13471347Spermatogenesis-associated protein 31A4PRO_0000313019Add
BLAST

Proteomic databases

PRIDEiQ4VX67.

PTM databases

PhosphoSiteiQ4VX67.

Expressioni

Gene expression databases

BgeeiQ4VX67.
GenevestigatoriQ4VX67.

Structurei

3D structure databases

ProteinModelPortaliQ4VX67.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi120 – 228109Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the SPATA31 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ4VX67.
PhylomeDBiQ4VX67.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4VX67-1 [UniParc]FASTAAdd to Basket

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MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF VLLPYLSYFR     50
CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ 100
LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS 150
PLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP 200
PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVAFPLGTV 250
PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 300
HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF 350
TNRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD 400
PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM 450
SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ 500
AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR 550
QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 600
QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG 650
ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE 700
LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV 750
RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL 800
GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG 850
AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 900
GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSIQQSRS LGAQSSKAGE 950
TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP 1000
RKLCLMEEVV NEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV 1050
SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRN PNCQGSCKSQ 1100
RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL 1150
LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSRVY 1200
SSSAEAQGLM TAVGQMLDKK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH 1250
RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ 1300
WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI 1347
Length:1,347
Mass (Da):148,755
Last modified:January 15, 2008 - v2
Checksum:iDBAF3B1CA2D4C3EE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596385 Genomic DNA. Translation: CAI95396.1.
UniGeneiHs.123004.
Hs.645497.

Genome annotation databases

EnsembliENST00000429767; ENSP00000411237; ENSG00000234214.

Polymorphism databases

DMDMi166233527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596385 Genomic DNA. Translation: CAI95396.1 .
UniGenei Hs.123004.
Hs.645497.

3D structure databases

ProteinModelPortali Q4VX67.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q4VX67.

Polymorphism databases

DMDMi 166233527.

Proteomic databases

PRIDEi Q4VX67.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000429767 ; ENSP00000411237 ; ENSG00000234214 .

Organism-specific databases

GeneCardsi GC09M041321.
HGNCi HGNC:32004. SPATA31A4.
neXtProti NX_Q4VX67.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000015250.
HOVERGENi HBG107892.
InParanoidi Q4VX67.
PhylomeDBi Q4VX67.

Miscellaneous databases

PROi Q4VX67.

Gene expression databases

Bgeei Q4VX67.
Genevestigatori Q4VX67.

Family and domain databases

InterProi IPR027970. DUF4599.
[Graphical view ]
Pfami PF15371. DUF4599. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiS31A4_HUMAN
AccessioniPrimary (citable) accession number: Q4VX67
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: July 9, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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