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Protein

Phosphotransferase

Gene

HK

Organism
Leishmania major
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:HKImported
ORF Names:LMJF_21_0240Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000000542 Componenti: Chromosome 21

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5664.LmjF.21.0240.

Structurei

3D structure databases

ProteinModelPortaliQ4VT70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 223Hexokinase_1InterPro annotationAdd BLAST192
Domaini230 – 465Hexokinase_2InterPro annotationAdd BLAST236

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
HOGENOMiHOG000162670.
KOiK00844.
OMAiTRRMVVE.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4VT70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARVNNLLS HIAIRDSDSE EMRYIKQRLA LASLATQFTM SSEKMKQLTM
60 70 80 90 100
YMIHEMVEGL EGRPSTVRML PSFVYTSDPA KATGVYYALD LGGTNFRVLR
110 120 130 140 150
VSLRGGKVDD RTDSKFVIPK SALVGDATDL FDFIAQSVKK MMSENAPDDL
160 170 180 190 200
EKRVPLGFTF SFPVDQKAVN KGLLIKWTKG FSTKNVEGND VVELLQASLR
210 220 230 240 250
RVRVNVNVVA LCNDTVGTLV ARYFVDTDVQ VGVIIGTGSN ACYFERASAV
260 270 280 290 300
TKDPAVSARG NAVTPINMEC GNFDSKYKYA LPITVYDDEM DAITPNRENQ
310 320 330 340 350
RQEKLVSGMY LGEISRRLIV HLAQLGCLPR GLVDGLCRPW AFESKHMGMI
360 370 380 390 400
AADQMPGLQF TRELIKRIAG VDMADISDLH TIRETCCLVR NRAAQQGAVF
410 420 430 440 450
TAAPMLKTRT QGLATVAVDG SVYEKTPSFQ RLYQECITSI LGSTSNVKVV
460 470
LQRDGSGVGA AMICALAANT K
Length:471
Mass (Da):51,720
Last modified:July 5, 2005 - v1
Checksum:i5938CBED6934FC51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY632239 Genomic DNA. Translation: AAV32454.1.
FR796417 Genomic DNA. Translation: CAJ03833.1.
RefSeqiXP_001682957.1. XM_001682905.1.

Genome annotation databases

EnsemblProtistsiLmjF.21.0240:mRNA; LmjF.21.0240:pep; LmjF.21.0240.
GeneDBiLmjF.21.0240:pep.
GeneIDi5651558.
KEGGilma:LMJF_21_0240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY632239 Genomic DNA. Translation: AAV32454.1.
FR796417 Genomic DNA. Translation: CAJ03833.1.
RefSeqiXP_001682957.1. XM_001682905.1.

3D structure databases

ProteinModelPortaliQ4VT70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5664.LmjF.21.0240.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiLmjF.21.0240:mRNA; LmjF.21.0240:pep; LmjF.21.0240.
GeneDBiLmjF.21.0240:pep.
GeneIDi5651558.
KEGGilma:LMJF_21_0240.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
HOGENOMiHOG000162670.
KOiK00844.
OMAiTRRMVVE.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4VT70_LEIMA
AccessioniPrimary (citable) accession number: Q4VT70
Secondary accession number(s): Q4QCJ1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.