IL13

Functionⁱ

GO - Molecular functionⁱ

cytokine receptor binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

immune response Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: IL13 proteinImported
Gene namesⁱ	Name:IL13Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB11914. Lebrikizumab.

DrugBankⁱ

DB11914. Lebrikizumab.

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q4VB53.

PeptideAtlasⁱ

Q4VB53.

Interactionⁱ

GO - Molecular functionⁱ

cytokine receptor binding Source: InterPro

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

SMRⁱ	Q4VB53.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410JCI3. Eukaryota. ENOG4111BX2. LUCA.
HOVERGENⁱ	HBG006140.

Family and domain databases

InterProⁱ	View protein in InterPro IPR009079. 4_helix_cytokine-like_core. IPR020470. IL-13. IPR001325. IL-4/IL-13.
PANTHERⁱ	PTHR45413. PTHR45413. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03487. IL13. 1 hit.
PRINTSⁱ	PR01929. INTRLEUKIN13.
SMARTⁱ	View protein in SMART SM00190. IL4_13. 1 hit.
SUPFAMⁱ	SSF47266. SSF47266. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q4VB53-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MVWSINLTAG MYCAALESLI NVSGCSAIEK TQRMLSGFCP HKVSAGQFSS 
        60         70         80 
LHVRDTKIEV AQFVKDLLLH LKKLFREGQF N

Length:81

Mass (Da):9,045

Last modified:July 5, 2005 - v1

Checksum:ⁱC31EF09FB2659584

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC096138 mRNA. Translation: AAH96138.1.
UniGeneⁱ	Hs.845.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q4VB53	P35225 UPI0000050AF5 UPI0000050AF6 Q4VB51 G3QPV1 UPI00029DB8F1 A0A0D9RMU3 UPI00045D532A A0A2K5UT95 Q0PW92 +23	Homo sapiens (Human) Gorilla gorilla gorilla (Western lowland gorilla) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Macaca mulatta (Rhesus macaque) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Papio anubis (Olive baboon) Colobus angolensis palliatus (Peters' Angolan colobus) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) And more	146	UniRef90_P35225	Cluster: Interleukin-13	34

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q4VB53	P35225 UPI0000050AF5 UPI0000050AF6 Q4VB51 G3QPV1 UPI00029DB8F1 H2PGI3 UPI0001D5E789 A0A2J8XDQ6 A0A2K6QKZ0 +28	Homo sapiens (Human) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Macaca mulatta (Rhesus macaque) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Colobus angolensis palliatus (Peters' Angolan colobus) Papio anubis (Olive baboon) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) And more	146	UniRef50_P35225	Cluster: Interleukin-13	39

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC096138 mRNA. Translation: AAH96138.1.
UniGeneⁱ	Hs.845.

3D structure databases

SMRⁱ	Q4VB53.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB11914. Lebrikizumab.

DrugBankⁱ

DB11914. Lebrikizumab.

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q4VB53.

PeptideAtlasⁱ

Q4VB53.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	ENOG410JCI3. Eukaryota. ENOG4111BX2. LUCA.
HOVERGENⁱ	HBG006140.

Miscellaneous databases

ChiTaRSⁱ	IL13. human.

ChiTaRSⁱ

IL13. human.

Family and domain databases

InterProⁱ	View protein in InterPro IPR009079. 4_helix_cytokine-like_core. IPR020470. IL-13. IPR001325. IL-4/IL-13.
PANTHERⁱ	PTHR45413. PTHR45413. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03487. IL13. 1 hit.
PRINTSⁱ	PR01929. INTRLEUKIN13.
SMARTⁱ	View protein in SMART SM00190. IL4_13. 1 hit.
SUPFAMⁱ	SSF47266. SSF47266. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q4VB53_HUMAN
Accessionⁱ	Q4VB53Primary (citable) accession number: Q4VB53
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2005
	Last sequence update:	July 5, 2005
	Last modified:	February 28, 2018
	This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - Q4VB53 (Q4VB53_HUMAN)

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IL13 protein

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Extracellular region or secreted

Pathology & Biotechⁱ

Chemistry databases

PTM / Processingⁱ

Proteomic databases

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Chemistry databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q4VB53 (Q4VB53_HUMAN)

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IL13 protein

IL13

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Chemistry databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ