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Q4VB53 - Q4VB53_HUMAN

UniProt

Q4VB53 - Q4VB53_HUMAN

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Protein
Submitted name:

IL13 protein

Gene

IL13

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular response to cytokine stimulus Source: Ensembl
  2. cellular response to mechanical stimulus Source: Ensembl
  3. microglial cell activation Source: Ensembl
  4. negative regulation of NAD(P)H oxidase activity Source: Ensembl
  5. negative regulation of neuron death Source: Ensembl
  6. negative regulation of transforming growth factor beta production Source: Ensembl
  7. positive regulation of B cell proliferation Source: Ensembl
  8. positive regulation of connective tissue growth factor production Source: Ensembl
  9. positive regulation of immunoglobulin production Source: Ensembl
  10. positive regulation of macrophage activation Source: Ensembl
  11. positive regulation of pancreatic stellate cell proliferation Source: Ensembl
  12. positive regulation of protein secretion Source: Ensembl
  13. positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
  14. positive regulation of smooth muscle cell proliferation Source: Ensembl
  15. positive regulation of tyrosine phosphorylation of Stat6 protein Source: Ensembl
  16. regulation of proton transport Source: Ensembl
  17. response to ethanol Source: Ensembl
  18. response to lipopolysaccharide Source: Ensembl
  19. response to nicotine Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
IL13 proteinImported
Gene namesi
Name:IL13Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. external side of plasma membrane Source: Ensembl
  3. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ4VB53.
ExpressionAtlasiQ4VB53. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ4VB53.
SMRiQ4VB53. Positions 1-81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006140.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR020470. IL-13.
[Graphical view]
PANTHERiPTHR11322. PTHR11322. 1 hit.
PRINTSiPR01929. INTRLEUKIN13.
SUPFAMiSSF47266. SSF47266. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4VB53-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVWSINLTAG MYCAALESLI NVSGCSAIEK TQRMLSGFCP HKVSAGQFSS 
        60         70         80 
LHVRDTKIEV AQFVKDLLLH LKKLFREGQF N
Length:81
Mass (Da):9,045
Last modified:July 5, 2005 - v1
Checksum:iC31EF09FB2659584
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC096138 mRNA. Translation: AAH96138.1.
UniGeneiHs.845.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC096138 mRNA. Translation: AAH96138.1.
UniGeneiHs.845.

3D structure databases

ProteinModelPortaliQ4VB53.
SMRiQ4VB53. Positions 1-81.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG006140.

Miscellaneous databases

ChiTaRSiIL13. human.

Gene expression databases

BgeeiQ4VB53.
ExpressionAtlasiQ4VB53. baseline and differential.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR020470. IL-13.
[Graphical view]
PANTHERiPTHR11322. PTHR11322. 1 hit.
PRINTSiPR01929. INTRLEUKIN13.
SUPFAMiSSF47266. SSF47266. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+Additional computationally mapped references.

Entry informationi

Entry nameiQ4VB53_HUMAN
AccessioniPrimary (citable) accession number: Q4VB53
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.