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Q4VB53

- Q4VB53_HUMAN

UniProt

Q4VB53 - Q4VB53_HUMAN

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Protein
Submitted name:

IL13 protein

Gene

IL13

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular response to cytokine stimulus Source: Ensembl
  2. cellular response to mechanical stimulus Source: Ensembl
  3. negative regulation of transforming growth factor beta production Source: Ensembl
  4. positive regulation of B cell proliferation Source: Ensembl
  5. positive regulation of connective tissue growth factor production Source: Ensembl
  6. positive regulation of immunoglobulin production Source: Ensembl
  7. positive regulation of macrophage activation Source: Ensembl
  8. positive regulation of pancreatic stellate cell proliferation Source: Ensembl
  9. positive regulation of protein secretion Source: Ensembl
  10. positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
  11. positive regulation of smooth muscle cell proliferation Source: Ensembl
  12. positive regulation of tyrosine phosphorylation of Stat6 protein Source: Ensembl
  13. regulation of proton transport Source: Ensembl
  14. response to ethanol Source: Ensembl
  15. response to lipopolysaccharide Source: Ensembl
  16. response to nicotine Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
IL13 proteinImported
Gene namesi
Name:IL13Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. external side of plasma membrane Source: Ensembl
  3. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ4VB53.
ExpressionAtlasiQ4VB53. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ4VB53.
SMRiQ4VB53. Positions 1-81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006140.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR020470. IL-13.
[Graphical view]
PANTHERiPTHR11322. PTHR11322. 1 hit.
PRINTSiPR01929. INTRLEUKIN13.
SUPFAMiSSF47266. SSF47266. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4VB53-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVWSINLTAG MYCAALESLI NVSGCSAIEK TQRMLSGFCP HKVSAGQFSS
60 70 80
LHVRDTKIEV AQFVKDLLLH LKKLFREGQF N
Length:81
Mass (Da):9,045
Last modified:July 5, 2005 - v1
Checksum:iC31EF09FB2659584
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC096138 mRNA. Translation: AAH96138.1.
UniGeneiHs.845.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC096138 mRNA. Translation: AAH96138.1 .
UniGenei Hs.845.

3D structure databases

ProteinModelPortali Q4VB53.
SMRi Q4VB53. Positions 1-81.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG006140.

Miscellaneous databases

ChiTaRSi IL13. human.

Gene expression databases

Bgeei Q4VB53.
ExpressionAtlasi Q4VB53. baseline and differential.

Family and domain databases

Gene3Di 1.20.1250.10. 1 hit.
InterProi IPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR020470. IL-13.
[Graphical view ]
PANTHERi PTHR11322. PTHR11322. 1 hit.
PRINTSi PR01929. INTRLEUKIN13.
SUPFAMi SSF47266. SSF47266. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiQ4VB53_HUMAN
AccessioniPrimary (citable) accession number: Q4VB53
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.