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Q4VB53

- Q4VB53_HUMAN

UniProt

Q4VB53 - Q4VB53_HUMAN

Protein
Submitted name:

IL13 protein

Gene

IL13

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Biological processi

    1. cellular response to cytokine stimulus Source: Ensembl
    2. cellular response to mechanical stimulus Source: Ensembl
    3. negative regulation of transforming growth factor beta production Source: Ensembl
    4. positive regulation of B cell proliferation Source: Ensembl
    5. positive regulation of connective tissue growth factor production Source: Ensembl
    6. positive regulation of immunoglobulin production Source: Ensembl
    7. positive regulation of macrophage activation Source: Ensembl
    8. positive regulation of pancreatic stellate cell proliferation Source: Ensembl
    9. positive regulation of protein secretion Source: Ensembl
    10. positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
    11. positive regulation of smooth muscle cell proliferation Source: Ensembl
    12. positive regulation of tyrosine phosphorylation of Stat6 protein Source: Ensembl
    13. regulation of proton transport Source: Ensembl
    14. response to ethanol Source: Ensembl
    15. response to lipopolysaccharide Source: Ensembl
    16. response to nicotine Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    IL13 proteinImported
    Gene namesi
    Name:IL13Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. external side of plasma membrane Source: Ensembl
    3. extracellular space Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ4VB53.
    BgeeiQ4VB53.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4VB53.
    SMRiQ4VB53. Positions 1-81.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG006140.

    Family and domain databases

    Gene3Di1.20.1250.10. 1 hit.
    InterProiIPR009079. 4_helix_cytokine-like_core.
    IPR012351. 4_helix_cytokine_core.
    IPR020470. IL-13.
    [Graphical view]
    PANTHERiPTHR11322. PTHR11322. 1 hit.
    PRINTSiPR01929. INTRLEUKIN13.
    SUPFAMiSSF47266. SSF47266. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4VB53-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVWSINLTAG MYCAALESLI NVSGCSAIEK TQRMLSGFCP HKVSAGQFSS   50
    LHVRDTKIEV AQFVKDLLLH LKKLFREGQF N 81
    Length:81
    Mass (Da):9,045
    Last modified:July 5, 2005 - v1
    Checksum:iC31EF09FB2659584
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC096138 mRNA. Translation: AAH96138.1.
    UniGeneiHs.845.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC096138 mRNA. Translation: AAH96138.1 .
    UniGenei Hs.845.

    3D structure databases

    ProteinModelPortali Q4VB53.
    SMRi Q4VB53. Positions 1-81.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG006140.

    Miscellaneous databases

    ChiTaRSi IL13. human.

    Gene expression databases

    ArrayExpressi Q4VB53.
    Bgeei Q4VB53.

    Family and domain databases

    Gene3Di 1.20.1250.10. 1 hit.
    InterProi IPR009079. 4_helix_cytokine-like_core.
    IPR012351. 4_helix_cytokine_core.
    IPR020470. IL-13.
    [Graphical view ]
    PANTHERi PTHR11322. PTHR11322. 1 hit.
    PRINTSi PR01929. INTRLEUKIN13.
    SUPFAMi SSF47266. SSF47266. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiQ4VB53_HUMAN
    AccessioniPrimary (citable) accession number: Q4VB53
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2005
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.