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Protein
Submitted name:

CYP11B1 protein

Gene

CYP11B1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotationSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
CYP11B1 proteinImported
Submitted name:
Cytochrome P450 11B1, mitochondrialImported
Gene namesi
Name:CYP11B1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:2591. CYP11B1.

PTM / Processingi

Proteomic databases

PeptideAtlasiQ4VAR0.

Expressioni

Gene expression databases

BgeeiENSG00000160882.

Structurei

3D structure databases

SMRiQ4VAR0. Positions 34-573.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119243.
HOGENOMiHOG000013161.
HOVERGENiHBG051098.
OMAiQYTSIVA.
OrthoDBiEOG091G0B8F.
PhylomeDBiQ4VAR0.

Family and domain databases

Gene3Di1.10.630.10. 3 hits.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002403. Cyt_P450_E_grp-IV.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00465. EP450IV.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4VAR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRAKAEVC MAVPWLSLQR AQALGTRAAR VPRTVLPFEA MPRRPGNRWL
60 70 80 90 100
RLLQIWREQG YEDLHLEVHQ TFQELGPIFR SRHSASFGRW GRSAARAGLW
110 120 130 140 150
RCQGRGWCRA NPSSLQRGQD SEALKYDLGG AGMVCVMLPE DVEKLQQVDS
160 170 180 190 200
LHPHRMSLEP WVAYRQHRGH KCGVFLLNVA DRGNSSPPFP GGIHGAPTHS
210 220 230 240 250
GCRNGPEWRF NRLRLNPEVL SPNAVQRFLP MVDAVARDFS QALKKKVLQN
260 270 280 290 300
ARGSLTLDVQ PSIFHYTIEA SNLALFGERL GLVGHSPSSA SLNFLHALEV
310 320 330 340 350
MFKSTVQLMF MPRSLSRWTS PKVWKEHFEA WDCIFQYGDN CIQKIYQELA
360 370 380 390 400
FSRPQQYTSI VAELLLNAEL SPDAIKANSM ELTAGSVDTT VFPLLMTLFE
410 420 430 440 450
LARNPNVQQA LRQESLAAAA SISEHPQKAT TELPLLRAAL KETLRLYPVG
460 470 480 490 500
LFLERVASSD LVLQNYHIPA GTLVRVFLYS LGRNPALFPR PERYNPQRWL
510 520 530 540 550
DIRGSGRNFY HVPFGFGMRQ CLGRRLAEAE MLLLLHHVLK HLQVETLTQE
560 570
DIKMVYSFIL RPSMFPLLTF RAIN
Length:574
Mass (Da):65,128
Last modified:July 5, 2005 - v1
Checksum:iD1C27D73E4B85775
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC083841 Genomic DNA. No translation available.
BC096285 mRNA. Translation: AAH96285.1.
UniGeneiHs.184927.

Genome annotation databases

EnsembliENST00000377675; ENSP00000366903; ENSG00000160882.
UCSCiuc010mey.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC083841 Genomic DNA. No translation available.
BC096285 mRNA. Translation: AAH96285.1.
UniGeneiHs.184927.

3D structure databases

SMRiQ4VAR0. Positions 34-573.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ4VAR0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377675; ENSP00000366903; ENSG00000160882.
UCSCiuc010mey.4. human.

Organism-specific databases

HGNCiHGNC:2591. CYP11B1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119243.
HOGENOMiHOG000013161.
HOVERGENiHBG051098.
OMAiQYTSIVA.
OrthoDBiEOG091G0B8F.
PhylomeDBiQ4VAR0.

Miscellaneous databases

ChiTaRSiCYP11B1. human.

Gene expression databases

BgeeiENSG00000160882.

Family and domain databases

Gene3Di1.10.630.10. 3 hits.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002403. Cyt_P450_E_grp-IV.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00465. EP450IV.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4VAR0_HUMAN
AccessioniPrimary (citable) accession number: Q4VAR0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.