Putative uncharacterized protein

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• GDP binding Source: Ensembl
• GTPase activity Source: Ensembl
• GTP binding Source: UniProtKB-KW
• myosin binding Source: Ensembl
• protein domain specific binding Source: Ensembl
• Rho GDP-dissociation inhibitor binding Source: Ensembl

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• actin cytoskeleton reorganization Source: Ensembl
• alpha-beta T cell lineage commitment Source: Ensembl
• androgen receptor signaling pathway Source: Ensembl
• angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure Source: Ensembl
• apical junction assembly Source: Ensembl
• apolipoprotein A-I-mediated signaling pathway Source: Ensembl
• beta selection Source: Ensembl
• cell-matrix adhesion Source: Ensembl
• cellular response to chemokine Source: Ensembl
• cerebral cortex cell migration Source: Ensembl
• endothelial cell migration Source: Ensembl
• endothelial tube lumen extension Source: Ensembl
• forebrain radial glial cell differentiation Source: Ensembl
• GTP metabolic process Source: Ensembl
• mitotic cleavage furrow formation Source: Ensembl
• mitotic spindle assembly Source: Ensembl
• negative chemotaxis Source: Ensembl
• negative regulation of cell migration involved in sprouting angiogenesis Source: Ensembl
• negative regulation of cell size Source: Ensembl
• negative regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
• negative regulation of intracellular steroid hormone receptor signaling pathway Source: Ensembl
• negative regulation of neuron apoptotic process Source: Ensembl
• negative regulation of neuron projection development Source: Ensembl
• negative regulation of oxidative phosphorylation Source: Ensembl
• negative regulation of reactive oxygen species biosynthetic process Source: Ensembl
• neuron projection morphogenesis Source: Ensembl
• odontogenesis Source: Ensembl
• ossification involved in bone maturation Source: Ensembl
• positive regulation of actin filament polymerization Source: Ensembl
• positive regulation of alpha-beta T cell differentiation Source: Ensembl
• positive regulation of cell growth Source: Ensembl
• positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
• positive regulation of cytokinesis Source: Ensembl
• positive regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
• positive regulation of lipase activity Source: Ensembl
• positive regulation of neuron apoptotic process Source: Ensembl
• positive regulation of neuron differentiation Source: Ensembl
• positive regulation of podosome assembly Source: Ensembl
• positive regulation of protein serine/threonine kinase activity Source: Ensembl
• positive regulation of stress fiber assembly Source: Ensembl
• positive regulation of T cell migration Source: Ensembl
• positive regulation of translation Source: Ensembl
• positive regulation of vascular smooth muscle contraction Source: Ensembl
• regulation of calcium ion transport Source: Ensembl
• regulation of dendrite development Source: Ensembl
• regulation of microtubule cytoskeleton organization Source: Ensembl
• regulation of modification of synaptic structure Source: Ensembl
• regulation of neural precursor cell proliferation Source: Ensembl
• regulation of osteoblast proliferation Source: Ensembl
• regulation of systemic arterial blood pressure by endothelin Source: Ensembl
• regulation of transcription from RNA polymerase II promoter Source: Ensembl
• response to amino acid Source: Ensembl
• response to drug Source: Ensembl
• response to ethanol Source: Ensembl
• response to glucocorticoid Source: Ensembl
• response to glucose Source: Ensembl
• response to hypoxia Source: Ensembl
• response to mechanical stimulus Source: Ensembl
• Rho protein signal transduction Source: Ensembl
• Roundabout signaling pathway Source: Ensembl
• skeletal muscle satellite cell migration Source: AgBase
• skeletal muscle tissue development Source: Ensembl
• stress-activated protein kinase signaling cascade Source: Ensembl
• stress fiber assembly Source: Ensembl
• substantia nigra development Source: Ensembl
• trabecula morphogenesis Source: Ensembl
• wound healing, spreading of cells Source: AgBase

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• apical junction complex Source: Ensembl
• axon Source: Ensembl
• cell cortex Source: Ensembl
• cleavage furrow Source: Ensembl
• cytosol Source: Ensembl
• dendritic spine Source: Ensembl
• endosome Source: Ensembl
• extracellular exosome Source: Ensembl
• extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
• focal adhesion Source: Ensembl
• lamellipodium Source: Ensembl
• mitochondrion Source: Ensembl
• nucleus Source: Ensembl
• ruffle membrane Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• myosin binding Source: Ensembl
• protein domain specific binding Source: Ensembl
• Rho GDP-dissociation inhibitor binding Source: Ensembl

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG 
        60         70         80         90        100
KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT 
       110        120        130        140        150
PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPVK PEEGRDMANR 
       160        170        180        190 
IGAFGYMECS AKTKDGVREV FEMATRAALQ ARRGKKKSGC LIL 

Sequence databases

Genome annotation databases

<p>This section provides links to the UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ