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Protein

PWWP domain-containing protein MUM1L1

Gene

Mum1l1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
PWWP domain-containing protein MUM1L1
Alternative name(s):
Mutated melanoma-associated antigen 1-like protein 1
Short name:
MUM1-like protein 1
Gene namesi
Name:Mum1l1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2445062. Mum1l1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 681681PWWP domain-containing protein MUM1L1PRO_0000257833Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei128 – 1281PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ4VA55.
PaxDbiQ4VA55.
PRIDEiQ4VA55.

PTM databases

iPTMnetiQ4VA55.
PhosphoSiteiQ4VA55.

Expressioni

Gene expression databases

BgeeiQ4VA55.
CleanExiMM_MUM1L1.
ExpressionAtlasiQ4VA55. baseline and differential.
GenevisibleiQ4VA55. MM.

Structurei

3D structure databases

ProteinModelPortaliQ4VA55.
SMRiQ4VA55. Positions 375-493.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini377 – 43862PWWPAdd
BLAST

Sequence similaritiesi

Belongs to the MUM1 family.Curated
Contains 1 PWWP domain.Curated

Phylogenomic databases

eggNOGiENOG410IKQG. Eukaryota.
ENOG4111FZN. LUCA.
GeneTreeiENSGT00390000001700.
HOGENOMiHOG000232141.
HOVERGENiHBG054002.
InParanoidiQ4VA55.
OMAiGMIVWFK.
OrthoDBiEOG7BS494.
PhylomeDBiQ4VA55.
TreeFamiTF328774.

Sequencei

Sequence statusi: Complete.

Q4VA55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGKYVLCNW KDQLWPAKVL DRSESPSESK RKNTSSLEVE ILSLDEKITV
60 70 80 90 100
ESTDTKVLSK SAVEAIMSSL AVQSEVIIAP REETAYERSL KMALEMVKEG
110 120 130 140 150
TNLSQESMSE EQPTATASEN VPEQPPDSPP HKKFRKLESN TQEDSASILL
160 170 180 190 200
CSESDDSMTD DKLQVHTTGE SMPSEMDTKA TENLGCCQTD PSLADEDDKK
210 220 230 240 250
EEKKKIDISA IMSVNLSLKE ESEYIKEEKF VPSSEDLTVP KEESQDILPE
260 270 280 290 300
APLAVSSECS IVSENNMEDP GEGPSNQNLV SYANQNQSSV ESDVGAETST
310 320 330 340 350
AGCSGDFQVS LPTRDTVSSD LLLQRLDLED LEEEARASGK LLSLNPASAA
360 370 380 390 400
ALENDNEDDD EDLPRFILHY ETRAFETGMI VWFKYQKYPF WPAVIKSIRR
410 420 430 440 450
KERKASVLLV EADMSPQKKG VRVSLRRLKK YDCKEKQALV EKAREEYRES
460 470 480 490 500
IDWCVSLICD YRVRLGCGSF TGSFFEYYAA DISYPVRKII KQDTFRNIFP
510 520 530 540 550
KLYNENVGEQ LPMASQAKRV SFQKILPDRM KPARDRANKN LVDFIVNAKG
560 570 580 590 600
TEDHLLGILK GTKKSKWLKS FLNAKSFTPC IETYFEDEDQ LDEVVKYLQE
610 620 630 640 650
IYKQIDQKML TLIKDDKIKF VLEVLLPEAI ICSISAVDGL DYEAAEAKYL
660 670 680
KGPSLGCRER ELYDSKILFE KRRRSLPNEG H
Length:681
Mass (Da):76,989
Last modified:October 31, 2006 - v2
Checksum:i9C9CC4524E3C68E1
GO

Sequence cautioni

The sequence BAC28940.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti85 – 851A → S in AAH96534 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732419 Genomic DNA. Translation: CAM46051.1.
BC053077 mRNA. Translation: AAH53077.1.
BC068178 mRNA. No translation available.
BC096534 mRNA. Translation: AAH96534.1.
BC120584 mRNA. Translation: AAI20585.1.
AK035086 mRNA. Translation: BAC28940.1. Different initiation.
CCDSiCCDS30432.2.
RefSeqiNP_001158102.1. NM_001164630.1.
NP_001158103.1. NM_001164631.1.
NP_001158104.1. NM_001164632.1.
NP_001158105.1. NM_001164633.1.
NP_780750.2. NM_175541.3.
XP_006528604.1. XM_006528541.1.
XP_006528606.1. XM_006528543.1.
XP_006528607.1. XM_006528544.1.
XP_006528608.1. XM_006528545.2.
UniGeneiMm.131001.

Genome annotation databases

EnsembliENSMUST00000113041; ENSMUSP00000108664; ENSMUSG00000042515.
ENSMUST00000113042; ENSMUSP00000108665; ENSMUSG00000042515.
ENSMUST00000113043; ENSMUSP00000108666; ENSMUSG00000042515.
ENSMUST00000113045; ENSMUSP00000108668; ENSMUSG00000042515.
GeneIDi245631.
KEGGimmu:245631.
UCSCiuc009ukc.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732419 Genomic DNA. Translation: CAM46051.1.
BC053077 mRNA. Translation: AAH53077.1.
BC068178 mRNA. No translation available.
BC096534 mRNA. Translation: AAH96534.1.
BC120584 mRNA. Translation: AAI20585.1.
AK035086 mRNA. Translation: BAC28940.1. Different initiation.
CCDSiCCDS30432.2.
RefSeqiNP_001158102.1. NM_001164630.1.
NP_001158103.1. NM_001164631.1.
NP_001158104.1. NM_001164632.1.
NP_001158105.1. NM_001164633.1.
NP_780750.2. NM_175541.3.
XP_006528604.1. XM_006528541.1.
XP_006528606.1. XM_006528543.1.
XP_006528607.1. XM_006528544.1.
XP_006528608.1. XM_006528545.2.
UniGeneiMm.131001.

3D structure databases

ProteinModelPortaliQ4VA55.
SMRiQ4VA55. Positions 375-493.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ4VA55.
PhosphoSiteiQ4VA55.

Proteomic databases

MaxQBiQ4VA55.
PaxDbiQ4VA55.
PRIDEiQ4VA55.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000113041; ENSMUSP00000108664; ENSMUSG00000042515.
ENSMUST00000113042; ENSMUSP00000108665; ENSMUSG00000042515.
ENSMUST00000113043; ENSMUSP00000108666; ENSMUSG00000042515.
ENSMUST00000113045; ENSMUSP00000108668; ENSMUSG00000042515.
GeneIDi245631.
KEGGimmu:245631.
UCSCiuc009ukc.2. mouse.

Organism-specific databases

CTDi139221.
MGIiMGI:2445062. Mum1l1.

Phylogenomic databases

eggNOGiENOG410IKQG. Eukaryota.
ENOG4111FZN. LUCA.
GeneTreeiENSGT00390000001700.
HOGENOMiHOG000232141.
HOVERGENiHBG054002.
InParanoidiQ4VA55.
OMAiGMIVWFK.
OrthoDBiEOG7BS494.
PhylomeDBiQ4VA55.
TreeFamiTF328774.

Miscellaneous databases

NextBioi386872.
PROiQ4VA55.
SOURCEiSearch...

Gene expression databases

BgeeiQ4VA55.
CleanExiMM_MUM1L1.
ExpressionAtlasiQ4VA55. baseline and differential.
GenevisibleiQ4VA55. MM.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain and Eye.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 91-681.
    Strain: C57BL/6J.
    Tissue: Embryonic breast.
  4. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-128, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Testis.

Entry informationi

Entry nameiMUML1_MOUSE
AccessioniPrimary (citable) accession number: Q4VA55
Secondary accession number(s): B1AW67
, Q0VBL8, Q7TSI2, Q8BS63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: January 20, 2016
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.