Q4VA53 (PDS5B_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sister chromatid cohesion protein PDS5 homolog B

Alternative name(s):
Androgen-induced proliferation inhibitor
Androgen-induced prostate proliferative shutoff-associated protein AS3

Gene names

Name:	Pds5b
Synonyms:	Aprin, As3, Kiaa0979

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1446 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells By similarity.
Subunit structure	Interacts with the cohesin complex. Interacts with RAD21; the interaction is direct. Interacts with WAPAL (via FGF motifs) or CDCA5 (via the FGF motif); the interaction is direct, cohesin-dependent and competitive By similarity.
Subcellular location	Nucleus By similarity UniProtKB Q6TRW4.
Tissue specificity	Expressed in prostate. Ref.1
Sequence similarities	Belongs to the PDS5 family. Contains 3 A.T hook DNA-binding domains. Contains 1 HEAT repeat.

Ontologies

Keywords
Biological process	Cell cycle Cell division Mitosis
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell division Inferred from electronic annotation. Source: UniProtKB-KW mitotic sister chromatid cohesion Inferred from sequence or structural similarity. Source: UniProtKB negative regulation of cell proliferation Inferred from sequence or structural similarity. Source: UniProtKB
Cellular_component	chromatin Inferred from electronic annotation. Source: Compara nucleus Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 Ref.1 (identifier: Q4VA53-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 Ref.2 (identifier: Q4VA53-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-529: Missing.
     1207-1230: SELEKPRSRKKAPVTDPEEKLGMD → VRVRCLVGRVMRLLIVIVLVIFAL
     1231-1446: Missing.

Note: No experimental confirmation available.

Isoform 3 Ref.2 (identifier: Q4VA53-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1206-1206: L → LVR

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1446	1446	Sister chromatid cohesion protein PDS5 homolog B		PRO_0000287425
Regions
	Repeat	383 – 419	37	HEAT
	DNA binding	1247 – 1259	13	A.T hook 1
	DNA binding	1285 – 1297	13	A.T hook 2
	DNA binding	1370 – 1382	13	A.T hook 3
Amino acid modifications
	Modified residue	1136	1	N6-acetyllysine By similarity
	Modified residue	1162	1	Phosphoserine By similarity
	Modified residue	1166	1	Phosphoserine Ref.8 UniProtKB Q9NTI5
	Modified residue	1176	1	Phosphoserine By similarity
	Modified residue	1182	1	Phosphoserine By similarity
	Modified residue	1191	1	Phosphoserine By similarity
	Modified residue	1255	1	Phosphoserine By similarity UniProtKB Q9NTI5
	Modified residue	1257	1	Phosphoserine Ref.8
	Modified residue	1281	1	Phosphoserine Ref.9
	Modified residue	1356	1	Phosphoserine Ref.5 Ref.6 Ref.7 Ref.8
	Modified residue	1365	1	Phosphothreonine By similarity
	Modified residue	1368	1	Phosphothreonine By similarity UniProtKB Q9NTI5
	Modified residue	1377	1	Phosphoserine By similarity UniProtKB Q9NTI5
	Modified residue	1381	1	Phosphoserine Ref.9 UniProtKB Q9NTI5
Natural variations
	Alternative sequence	1 – 529	529	Missing in isoform 2. Ref.2		VSP_052403
	Alternative sequence	1206	1	L → LVR in isoform 3. Ref.2		VSP_052404
	Alternative sequence	1207 – 1230	24	SELEK…KLGMD → VRVRCLVGRVMRLLIVIVLV IFAL in isoform 2. Ref.2		VSP_052405
	Alternative sequence	1231 – 1446	216	Missing in isoform 2. Ref.2		VSP_052406
Experimental info
	Sequence conflict	496	1	W → R in AAM52216. Ref.1
	Sequence conflict	966	1	I → T in AAM52216. Ref.1
	Sequence conflict	978	1	A → S in AAM52216. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 3540041DE3C7FCBE	FASTA	1,446	164,419
	10 20 30 40 50 60 MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA 70 80 90 100 110 120 LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT 130 140 150 160 170 180 KSPQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFSVINNGHN QKVHMHMVDL 190 200 210 220 230 240 MSSIICEGDT VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV 250 260 270 280 290 300 LMLGKTSISD LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF 310 320 330 340 350 360 GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD LTEYLKVRSH 370 380 390 400 410 420 DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYS 430 440 450 460 470 480 LQSAAGKDAA KQISWVKDKL LHIYYQNSID DRLLVERIFA QYMVPHNLET TERMKCLYYL 490 500 510 520 530 540 YATLDLNAVK ALNEMWKCQN LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG 550 560 570 580 590 600 KAQDFMKKFT QVLEDDEKIR KQLEALVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM 610 620 630 640 650 660 IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL ELLKVLSFTH 670 680 690 700 710 720 PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE EDFPHIRSAL LPVLHHKSKK 730 740 750 760 770 780 GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP LHKSLDPSNL EHLITPLVTI GHIALLAPDQ 790 800 810 820 830 840 FAAPLKSLVA TFIVKDLLMN DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK 850 860 870 880 890 900 NNHSKSGTST LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT 910 920 930 940 950 960 LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP VKERRAHARQ 970 980 990 1000 1010 1020 CLVKNITVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA HDPDYVKVQD IEQLKDVKEC 1030 1040 1050 1060 1070 1080 LWFVLEILMA KNENNSHAFI RKMVENIKQT KDAQGPDDTK MNEKLYTVCD VAMNIIMSKS 1090 1100 1110 1120 1130 1140 TTYSLESPKD PVLPARFFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKTANV LGAVNKPLSS 1150 1160 1170 1180 1190 1200 AGKQSQTKSS RMETVSNASS SSNPSSPGRI KGRLDSSEMD HSENEDYTMS SPLPGKKSDK 1210 1220 1230 1240 1250 1260 REDPDLSELE KPRSRKKAPV TDPEEKLGMD DLTKLVQEQK PKGSQRGRKR GRTASDSDEQ 1270 1280 1290 1300 1310 1320 QWPEEKRHKE ELLENEDEQN SPPKKGKRGR PPKPLGGGTS KEEPTMKTSK KGNKKKLVPP 1330 1340 1350 1360 1370 1380 VVDDDEEEER QIGNTEHKSK SKQHRTSKRA QQRAESPETS AVESTQSTPQ KGRGRPSKAP 1390 1400 1410 1420 1430 1440 SPSQPPKKIR VGRSKQVATK ENDSSEEMDV LQASSPVSDD TTQEGAEEED ISVGNVRRRS SKRERR
	Isoform 2 [UniParc]. Checksum: FAF6F0351AF7869B	FASTA	701	78,714
	10 20 30 40 50 60 MVITRNLPDP GKAQDFMKKF TQVLEDDEKI RKQLEALVSP TCSCKQAEGC VREITKKLGN 70 80 90 100 110 120 PKQPTNPFLE MIKFLLERIA PVHIDTESIS ALIKQVNKSI DGTADDEDEG VPTDQAIRAG 130 140 150 160 170 180 LELLKVLSFT HPISFHSAET FESLLACLKM DDEKVAEAAL QIFKNTGSKI EEDFPHIRSA 190 200 210 220 230 240 LLPVLHHKSK KGPPRQAKYA IHCIHAIFSS KETQFAQIFE PLHKSLDPSN LEHLITPLVT 250 260 270 280 290 300 IGHIALLAPD QFAAPLKSLV ATFIVKDLLM NDRLPGKKTT KLWVPDEEVS PETMVKIQAI 310 320 330 340 350 360 KMMVRWLLGM KNNHSKSGTS TLRLLTTILH SDGDLTEQGK ISKPDMSRLR LAAGSAIVKL 370 380 390 400 410 420 AQEPCYHEII TLEQYQLCAL AINDECYQVR QVFAQKLHKG LSRLRLPLEY MAICALCAKD 430 440 450 460 470 480 PVKERRAHAR QCLVKNITVR REYLKQHAAV SEKLLSLLPE YVVPYTIHLL AHDPDYVKVQ 490 500 510 520 530 540 DIEQLKDVKE CLWFVLEILM AKNENNSHAF IRKMVENIKQ TKDAQGPDDT KMNEKLYTVC 550 560 570 580 590 600 DVAMNIIMSK STTYSLESPK DPVLPARFFT QPDKNFSNTK NYLPPEMKSF FTPGKPKTAN 610 620 630 640 650 660 VLGAVNKPLS SAGKQSQTKS SRMETVSNAS SSSNPSSPGR IKGRLDSSEM DHSENEDYTM 670 680 690 700 SSPLPGKKSD KREDPDLVRV RCLVGRVMRL LIVIVLVIFA L
	Isoform 3 [UniParc]. Checksum: 80CFDE441169F45E	FASTA	1,448	164,674
	10 20 30 40 50 60 MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA 70 80 90 100 110 120 LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT 130 140 150 160 170 180 KSPQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFSVINNGHN QKVHMHMVDL 190 200 210 220 230 240 MSSIICEGDT VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV 250 260 270 280 290 300 LMLGKTSISD LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF 310 320 330 340 350 360 GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD LTEYLKVRSH 370 380 390 400 410 420 DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYS 430 440 450 460 470 480 LQSAAGKDAA KQISWVKDKL LHIYYQNSID DRLLVERIFA QYMVPHNLET TERMKCLYYL 490 500 510 520 530 540 YATLDLNAVK ALNEMWKCQN LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG 550 560 570 580 590 600 KAQDFMKKFT QVLEDDEKIR KQLEALVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM 610 620 630 640 650 660 IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL ELLKVLSFTH 670 680 690 700 710 720 PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE EDFPHIRSAL LPVLHHKSKK 730 740 750 760 770 780 GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP LHKSLDPSNL EHLITPLVTI GHIALLAPDQ 790 800 810 820 830 840 FAAPLKSLVA TFIVKDLLMN DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK 850 860 870 880 890 900 NNHSKSGTST LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT 910 920 930 940 950 960 LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP VKERRAHARQ 970 980 990 1000 1010 1020 CLVKNITVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA HDPDYVKVQD IEQLKDVKEC 1030 1040 1050 1060 1070 1080 LWFVLEILMA KNENNSHAFI RKMVENIKQT KDAQGPDDTK MNEKLYTVCD VAMNIIMSKS 1090 1100 1110 1120 1130 1140 TTYSLESPKD PVLPARFFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKTANV LGAVNKPLSS 1150 1160 1170 1180 1190 1200 AGKQSQTKSS RMETVSNASS SSNPSSPGRI KGRLDSSEMD HSENEDYTMS SPLPGKKSDK 1210 1220 1230 1240 1250 1260 REDPDLVRSE LEKPRSRKKA PVTDPEEKLG MDDLTKLVQE QKPKGSQRGR KRGRTASDSD 1270 1280 1290 1300 1310 1320 EQQWPEEKRH KEELLENEDE QNSPPKKGKR GRPPKPLGGG TSKEEPTMKT SKKGNKKKLV 1330 1340 1350 1360 1370 1380 PPVVDDDEEE ERQIGNTEHK SKSKQHRTSK RAQQRAESPE TSAVESTQST PQKGRGRPSK 1390 1400 1410 1420 1430 1440 APSPSQPPKK IRVGRSKQVA TKENDSSEEM DVLQASSPVS DDTTQEGAEE EDISVGNVRR RSSKRERR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The AS3 proliferative arrest gene has an ancient eukaryotic heritage and shows highly conserved functional domains in mice." Geck P., Maffini M., Sonnenschein C., Soto A.M. Proc. Annu. Meet. Am. Assoc. Cancer Res. 43:987-987(2002) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY. Strain: BALB/c. Tissue: Brain.
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 625-1446 (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1092-1446 (ISOFORM 1). Strain: C57BL/6J. Tissue: Cerebellum, Embryo, Head and Thymus.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: C57BL/6. Tissue: Brain.
[4]	"Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H. DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 256-1446 (ISOFORM 1). Tissue: Brain.
[5]	"Phosphoproteomic analysis of the developing mouse brain." Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P. Mol. Cell. Proteomics 3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1356, MASS SPECTROMETRY. Tissue: Embryonic brain.
[6]	"Comprehensive identification of phosphorylation sites in postsynaptic density preparations." Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L. Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1356, MASS SPECTROMETRY.
[7]	"Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry." Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R. J. Proteome Res. 6:250-262(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1356, MASS SPECTROMETRY. Tissue: Liver.
[8]	"Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1166; SER-1257 AND SER-1356, MASS SPECTROMETRY. Tissue: Liver.
[9]	"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1281 AND SER-1381, MASS SPECTROMETRY. Tissue: Melanoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY102267 mRNA. Translation: AAM52216.1. AK041682 mRNA. Translation: BAC31031.1. AK045159 mRNA. Translation: BAC32242.1. AK048706 mRNA. Translation: BAC33427.1. AK164853 mRNA. Translation: BAE37943.1. BC096539 mRNA. Translation: AAH96539.1. AK122414 mRNA. Translation: BAC65696.1.
IPI	IPI00317401. IPI00776026. IPI00845638.
RefSeq	NP_780519.3. NM_175310.6.
UniGene	Mm.32959.
3D structure databases
ProteinModelPortal	Q4VA53.
SMR	Q4VA53. Positions 274-300.
ModBase	Search...
PTM databases
PhosphoSite	Q4VA53.
Proteomic databases
PaxDb	Q4VA53.
PRIDE	Q4VA53.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000016569; ENSMUSP00000016569; ENSMUSG00000034021. ENSMUST00000110486; ENSMUSP00000106112; ENSMUSG00000034021.
GeneID	100710.
KEGG	mmu:100710.
UCSC	uc009auh.1. mouse. uc009aui.1. mouse. uc009auj.1. mouse.
Organism-specific databases
CTD	23047.
MGI	MGI:2140945. Pds5b.
Rouge	Search...
Phylogenomic databases
eggNOG	NOG268017.
GeneTree	ENSGT00390000012488.
HOVERGEN	HBG108241.
InParanoid	Q4VA53.
KO	K11267.
OrthoDB	EOG46T30N.
Gene expression databases
ArrayExpress	Q4VA53.
Bgee	Q4VA53.
Genevestigator	Q4VA53.
Family and domain databases
Gene3D	1.25.10.10. 4 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR017956. AT_hook_DNA-bd_motif. [Graphical view]
SMART	SM00384. AT_hook. 3 hits. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
PROSITE	PS50077. HEAT_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	354602.
SOURCE	Search...

Entry information

Entry name

PDS5B_MOUSE

Accession

Primary (citable) accession number: Q4VA53
Secondary accession number(s): Q3TNZ4 , Q7TSS4, Q80TM8, Q8BJ18, Q8BLH6, Q8BX77

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program