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Protein

WD repeat-containing protein 78

Gene

Wdr78

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein 78
Gene namesi
Name:Wdr78
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1311027. Wdr78.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002627741 – 803WD repeat-containing protein 78Add BLAST803

Proteomic databases

PaxDbiQ4V8G4.
PRIDEiQ4V8G4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000006999.
GenevisibleiQ4V8G4. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000048851.

Structurei

3D structure databases

ProteinModelPortaliQ4V8G4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati492 – 532WD 1Add BLAST41
Repeati541 – 589WD 2Add BLAST49
Repeati660 – 700WD 3Add BLAST41
Repeati703 – 742WD 4Add BLAST40
Repeati748 – 787WD 5Add BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili396 – 422Sequence analysisAdd BLAST27

Sequence similaritiesi

Contains 5 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

eggNOGiENOG410IU36. Eukaryota.
ENOG410YJ9J. LUCA.
GeneTreeiENSGT00730000110228.
HOGENOMiHOG000148595.
HOVERGENiHBG059084.
InParanoidiQ4V8G4.
OMAiCSADWSI.
OrthoDBiEOG091G07ZY.
PhylomeDBiQ4V8G4.
TreeFamiTF300553.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4V8G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSSPTSTRK QTNFTASVSA QSRKSISFGN PKSTGGKGYA GANQSKIVAS
60 70 80 90 100
RTMTFLPEMK PAEKLNIASA KLVQVLDPRG VDVTPRPLYH PDPHAMPTKP
110 120 130 140 150
SKLLTSQEGS MGSDYISSYS LYQNTLNPSM LGQYTRSVIG SSSTVSKSSI
160 170 180 190 200
STTESMTEDL EDPSYKRDRL ASFADVRVMR APAEAAITKE ELERNVEIFL
210 220 230 240 250
METETLRFFD LPTVMISTDS EEAEKVIEKN INYEILCRNR LGNDLYVERM
260 270 280 290 300
MQTFNGAPKN KDVQCDKIIM EEKGVMATTW DLYDSFNIPE ASLAAKRSAY
310 320 330 340 350
LSKASLLVRD RDPKIQDSES SSLMDIESVI LAKSHEDEED NSEKILKSDK
360 370 380 390 400
LHQDLFYMER VLMENVFQPK LAAYRQLPIY KELEPGQPEE DLQVVNKVTE
410 420 430 440 450
DEVKKDEEEE METELEIEIT TEQSTIPANL ERLWSFSCDL TKGLNVSSLS
460 470 480 490 500
WNKANSDLLA VGYGNFGFKE QKRGMACCWS IKNPMWPERI YQSPYGVTSV
510 520 530 540 550
DFSISSPNLL AVGYHNGTVA IYNVQSNHNT PVLDSSESPQ KHLGPVWQVQ
560 570 580 590 600
WIEQDRGTTG DDRREILVSI SADGRISKWV IRKGLDCHDL MHLKRTTVTS
610 620 630 640 650
SKKGIEKEKK GEALISRQAP GMCFAFHTKD TNIYLAGTEE GLIHKCSCSY
660 670 680 690 700
NEQYLETYRG HKGPVYKVTW NPFCPDVFLS CSADWGVMIW HQDNVKPFFT
710 720 730 740 750
FYPTTYVVYD VAWSPKSAYI FAAANENRVE IWDLQISTLD PLIVNVANPG
760 770 780 790 800
IKFTTVLFAK QTDCLLVGDS DGQVAVYELR NMPTPTESGR GDVINVLLGP

KAN
Length:803
Mass (Da):90,198
Last modified:July 5, 2005 - v1
Checksum:i77573CC6C09BDACD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083631 mRNA. Translation: AAH83631.1.
BC097402 mRNA. Translation: AAH97402.1.
RefSeqiNP_001019957.1. NM_001024786.1.
UniGeneiRn.162077.

Genome annotation databases

EnsembliENSRNOT00000046691; ENSRNOP00000048851; ENSRNOG00000006999.
GeneIDi313417.
KEGGirno:313417.
UCSCiRGD:1311027. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083631 mRNA. Translation: AAH83631.1.
BC097402 mRNA. Translation: AAH97402.1.
RefSeqiNP_001019957.1. NM_001024786.1.
UniGeneiRn.162077.

3D structure databases

ProteinModelPortaliQ4V8G4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000048851.

Proteomic databases

PaxDbiQ4V8G4.
PRIDEiQ4V8G4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000046691; ENSRNOP00000048851; ENSRNOG00000006999.
GeneIDi313417.
KEGGirno:313417.
UCSCiRGD:1311027. rat.

Organism-specific databases

CTDi79819.
RGDi1311027. Wdr78.

Phylogenomic databases

eggNOGiENOG410IU36. Eukaryota.
ENOG410YJ9J. LUCA.
GeneTreeiENSGT00730000110228.
HOGENOMiHOG000148595.
HOVERGENiHBG059084.
InParanoidiQ4V8G4.
OMAiCSADWSI.
OrthoDBiEOG091G07ZY.
PhylomeDBiQ4V8G4.
TreeFamiTF300553.

Miscellaneous databases

PROiQ4V8G4.

Gene expression databases

BgeeiENSRNOG00000006999.
GenevisibleiQ4V8G4. RN.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWDR78_RAT
AccessioniPrimary (citable) accession number: Q4V8G4
Secondary accession number(s): Q5XIP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: July 5, 2005
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.