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Protein

Proton-coupled amino acid transporter 3

Gene

Slc36a3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Proton-coupled amino acid transporter 3
Short name:
Proton/amino acid transporter 3
Alternative name(s):
Solute carrier family 36 member 3
Tramdorin-2
Gene namesi
Name:Slc36a3
Synonyms:Pat3, Tramd2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1309092. Slc36a3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5454CytoplasmicSequence analysisAdd
BLAST
Transmembranei55 – 7521HelicalSequence analysisAdd
BLAST
Topological domaini76 – 772ExtracellularSequence analysis
Transmembranei78 – 9821HelicalSequence analysisAdd
BLAST
Topological domaini99 – 14446CytoplasmicSequence analysisAdd
BLAST
Transmembranei145 – 16521HelicalSequence analysisAdd
BLAST
Topological domaini166 – 20237ExtracellularSequence analysisAdd
BLAST
Transmembranei203 – 22321HelicalSequence analysisAdd
BLAST
Topological domaini224 – 2252CytoplasmicSequence analysis
Transmembranei226 – 24621HelicalSequence analysisAdd
BLAST
Topological domaini247 – 25913ExtracellularSequence analysisAdd
BLAST
Transmembranei260 – 28021HelicalSequence analysisAdd
BLAST
Topological domaini281 – 29111CytoplasmicSequence analysisAdd
BLAST
Transmembranei292 – 31221HelicalSequence analysisAdd
BLAST
Topological domaini313 – 34432ExtracellularSequence analysisAdd
BLAST
Transmembranei345 – 36521HelicalSequence analysisAdd
BLAST
Topological domaini366 – 3749CytoplasmicSequence analysis
Transmembranei375 – 39521HelicalSequence analysisAdd
BLAST
Topological domaini396 – 3994ExtracellularSequence analysis
Transmembranei400 – 42021HelicalSequence analysisAdd
BLAST
Topological domaini421 – 43919CytoplasmicSequence analysisAdd
BLAST
Transmembranei440 – 46021HelicalSequence analysisAdd
BLAST
Topological domaini461 – 47717ExtracellularSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Proton-coupled amino acid transporter 3PRO_0000326206Add
BLAST

Proteomic databases

PaxDbiQ4V8B1.
PRIDEiQ4V8B1.

Expressioni

Gene expression databases

GenevisibleiQ4V8B1. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000037827.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi28 – 336Poly-Ser

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1304. Eukaryota.
COG0814. LUCA.
GeneTreeiENSGT00390000011245.
HOGENOMiHOG000006823.
HOVERGENiHBG057183.
InParanoidiQ4V8B1.
KOiK14209.
OMAiPTWISIH.
OrthoDBiEOG73V6KC.
PhylomeDBiQ4V8B1.
TreeFamiTF314873.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4V8B1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKTPLLRED GRCQRNTFGG SKASSKGSSS SSSNNTVSSK KKPRRKADAL
60 70 80 90 100
MFIQIFIHLL KSNIGTGFLG LPLAVKNAGL LVGPVSLLAI GALTVHCMDI
110 120 130 140 150
LLNCACHLTS RLQRSFVNYE ETTMYSLETC PSPWLRTHSV WGRYVVSFLL
160 170 180 190 200
IVTQLGFCSV YFMFMADNLQ QIVEEAHFTS NVCQPRQSLV MTSILDTRFY
210 220 230 240 250
MLTILPFLIL LVLVQNPQVL SIFSTLATIT TLSSLALIFE YLIQIPHHSH
260 270 280 290 300
LPLVASWKTF LLFFGTAIFT FEGVGMVLPL KSQMKSPQQF PAVLYLGMSF
310 320 330 340 350
VIFLYICLGT LGYMKFGADT QASITLNLPN CWLYQSVKLM YSVGIFFTYA
360 370 380 390 400
LQFHVPAEII VPYVVSRASE NWALFIDLTV RAALVCLTCF SAVLIPRLDL
410 420 430 440 450
VISLVGSVSS SALALIIPPL LEIATFYSEN ISCTTIAKDI MISILGLLGC
460 470
VLGTYQALYE MTQQSRFPML NSTNVHT
Length:477
Mass (Da):52,850
Last modified:July 5, 2005 - v1
Checksum:i62E8D79CB75452D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC097463 mRNA. Translation: AAH97463.1.
RefSeqiNP_001019935.1. NM_001024764.1.
XP_008765907.1. XM_008767685.1.
UniGeneiRn.75959.

Genome annotation databases

EnsembliENSRNOT00000037274; ENSRNOP00000037827; ENSRNOG00000021310.
GeneIDi303148.
KEGGirno:303148.
UCSCiRGD:1309092. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC097463 mRNA. Translation: AAH97463.1.
RefSeqiNP_001019935.1. NM_001024764.1.
XP_008765907.1. XM_008767685.1.
UniGeneiRn.75959.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000037827.

Proteomic databases

PaxDbiQ4V8B1.
PRIDEiQ4V8B1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000037274; ENSRNOP00000037827; ENSRNOG00000021310.
GeneIDi303148.
KEGGirno:303148.
UCSCiRGD:1309092. rat.

Organism-specific databases

CTDi285641.
RGDi1309092. Slc36a3.

Phylogenomic databases

eggNOGiKOG1304. Eukaryota.
COG0814. LUCA.
GeneTreeiENSGT00390000011245.
HOGENOMiHOG000006823.
HOVERGENiHBG057183.
InParanoidiQ4V8B1.
KOiK14209.
OMAiPTWISIH.
OrthoDBiEOG73V6KC.
PhylomeDBiQ4V8B1.
TreeFamiTF314873.

Miscellaneous databases

NextBioi650741.
PROiQ4V8B1.

Gene expression databases

GenevisibleiQ4V8B1. RN.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiS36A3_RAT
AccessioniPrimary (citable) accession number: Q4V8B1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: July 5, 2005
Last modified: May 11, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.