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Q4V054 (Q4V054_XANC8) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:XC_0232 EMBL AAY47319.1
OrganismXanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP] EMBL AAY47319.1
Taxonomic identifier314565 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain150 – 353204ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding180 – 23556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3071Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3201Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3201Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3221Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
Q4V054 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 01E285702AF9D15F

FASTA37340,110
        10         20         30         40         50         60 
MTGAGMRRIR VGLIFGGKSA EHEVSLQSAR NILQALDPQR FEPVLIGIDK QGQWHLSAQE 

        70         80         90        100        110        120 
SFLLDADDPS RIALRHSGRG LAVLPGAASA QLRAVDAEQA LAQIDVVFPI VHGTLGEDGS 

       130        140        150        160        170        180 
LQGLLRMANL PFVGSGVLGS AVAMDKDMAK RVLRDAGLEV APFACFTRHT AAQADVQTLI 

       190        200        210        220        230        240 
AQFGLPLFVK PANQGSSVGV SQVRSAEEFS AALELALRYD HKVLVEAAIA GREIECAVLG 

       250        260        270        280        290        300 
NATPQASVCG EVVVHDAFYS YQTKYIRDDG AATVIPADID AHTQHRIQQC ALQAYQALDC 

       310        320        330        340        350        360 
AGMARVDVFL CADGRIVINE VNTLPGFTRI SMYPKLWEAS GLDYRSLVTR LIELALERHA 

       370 
DDGRLYSSVV THA 

« Hide

References

[1]"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
Qian W., Jia Y., Ren S.X., He Y.Q., Feng J.X., Lu L.F., Sun Q., Ying G., Tang D.J., Tang H., Wu W., Hao P., Wang L., Jiang B.L., Zeng S., Gu W.Y., Lu G., Rong L. expand/collapse author list , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.P., Tang J.L., He C.
Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8004 EMBL AAY47319.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000050 Genomic DNA. Translation: AAY47319.1.
RefSeqYP_241339.2. NC_007086.1.

3D structure databases

ProteinModelPortalQ4V054.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING314565.XC_0232.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY47319; AAY47319; XC_0232.
GeneID3381623.
KEGGxcb:XC_0232.
PATRIC24061672. VBIXanCam24967_0248.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011593.
KOK01921.
OMAQIDVIFP.
OrthoDBEOG64BQ73.

Enzyme and pathway databases

BioCycXCAM314565:GCQG-229-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4V054_XANC8
AccessionPrimary (citable) accession number: Q4V054
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)