Reviewed,
UniProtKB/Swiss-Prot Q4UZI9 (HGD_XANC8)
Last modified
November 4, 2008.
Version 22.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Homogentisate 1,2-dioxygenase EC=1.13.11.5 Alternative name(s): Homogentisicase Homogentisate oxygenase Homogentisic acid oxidase | ||||
| Gene names |
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| Organism | Xanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 314565 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas |
Protein attributes
| Sequence length | 455 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Homogentisate + O(2) = 4-maleylacetoacetate. |
| Cofactor | Iron By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the homogentisate dioxygenase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Phenylalanine catabolism Tyrosine catabolism |
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | L-phenylalanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW tyrosine catabolic processInferred from electronic annotation. Source: HAMAP |
| Molecular function | homogentisate 1,2-dioxygenase activity Inferred from electronic annotation. Source: HAMAP iron ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris." Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. He C.Genome Res. 15:757-767(2005) [PubMed: 15899963] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000050 Genomic DNA. Translation: AAY47534.1. | |
| RefSeq | YP_241554.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3382101. |
| GenomeReviews | Gene locus XC_0452 in contig CP000050_GR. |
| KEGG | xcb:XC_0452. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q4UZI9. |
Enzyme and pathway databases | |
| BioCyc | XCAM314565:XC_0452-MON. |
Family and domain databases | |
| HAMAP | MF_00334. [Tree] |
| InterPro | IPR005708. Homogentis_dOase. [Graphical view] |
| PANTHER | PTHR11056. Homogentis_dOase. 1 hit. |
| Pfam | PF04209. HgmA. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01015. hmgA. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | HGD_XANC8 | ||||||||
| Accession | Primary (citable) accession number: Q4UZI9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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