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Q4UYN4 (BETB_XANC8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:XC_0761
OrganismXanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP]
Taxonomic identifier314565 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas ›

Protein attributes

Sequence length490 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP-Rule MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP-Rule MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycine betaine biosynthetic process from choline

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 490490Betaine aldehyde dehydrogenase HAMAP-Rule MF_00804
PRO_0000056560

Regions

Nucleotide binding229 – 2346NAD By similarity

Sites

Active site2521 By similarity
Active site2861 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UYN4 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 25795922C6CA4786

FASTA49052,498
        10         20         30         40         50         60 
MPRFPDQLLY IGGRYVPARG GHTFEVVNPA TGEVLANVHN ADADDLDAAV DSAKAGQRHW 

        70         80         90        100        110        120 
AALTVVERSR ILLRAVALLR ERNDALAELE TLNTGKPLSE TRSVDIVTGA DVLEYYAGVA 

       130        140        150        160        170        180 
QALQGVQVPL REGSFFYTRH EPLGVVGAIG AWNYPIQIAL WKAAPALAAG NAMIFKPSEV 

       190        200        210        220        230        240 
TPLTALKLAE IFTEAGLPDG VFNVLPGDGA SVGHALTEHP EIEKISFTGG TATGRKVMAS 

       250        260        270        280        290        300 
ASSSSLKDVT MELGGKSPLI VCADADLDLA ADIAMMANFY SSGQVCTNGT RVFVPRALRT 

       310        320        330        340        350        360 
AFEARLLARV QRIHIGDPLD ERTTFGPMVS AAHMQRVLEH IEQGKAEGAR LLCGGERLRD 

       370        380        390        400        410        420 
GALAQGCYVA PTIFSDCTDV MTIVREEIFG PVLSLLTYDD EDEAITRANA TSYGLAAGVV 

       430        440        450        460        470        480 
TPDLSRAHRL IHRLEAGICW INTWGESPAP MPVGGYKQSG VGRENGLATL QAYTRTKSVQ 

       490 
VELERYASVF

« Hide

References

[1]"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. expand/collapse author list , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.
Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8004.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000050 Genomic DNA. Translation: AAY47839.1.
RefSeqYP_241859.1. NC_007086.1.

3D structure databases

ProteinModelPortalQ4UYN4.
ModBaseSearch...

Protein-protein interaction databases

STRING314565.XC_0761.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY47839; AAY47839; XC_0761.
GeneID3382402.
KEGGxcb:XC_0761.
PATRIC24062820. VBIXanCam24967_0820.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00130.
OMAGTDTGKK.
ProtClustDBPRK13252.

Enzyme and pathway databases

UniPathwayUPA00529; UER00386.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
HAMAPMF_00804. BADH.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_XANC8
AccessionPrimary (citable) accession number: Q4UYN4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 5, 2005
Last modified: May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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