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Q4UX36 (MURA_XANC8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
EC=2.5.1.7
Alternative name(s):
Enoylpyruvate transferase
UDP-N-acetylglucosamine enolpyruvyl transferase
Short name=EPT
Gene names
Name:murA
Ordered Locus Names:XC_1318
OrganismXanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP]
Taxonomic identifier314565 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas ›

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 424424UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111
PRO_0000231301

Sites

Active site1221Proton donor By similarity

Amino acid modifications

Modified residue12212-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UX36 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 3E62A81EA5832EA8

FASTA42444,445
        10         20         30         40         50         60 
MAKIVVTGGQ ALHGEVHISG AKNAVLPILC ATLLADAPVE ISNVPHLHDV ITTVKLLSEL 

        70         80         90        100        110        120 
GAEVTIDEGT LAKGRSILVD PRSVTHQIAP YELVKTMRAS ILVLGPLLAR YGTAEVSLPG 

       130        140        150        160        170        180 
GCAIGSRPVD QHIKGLQALG ADISVENGYI KATSNGRLKG GRYVFDMVSV TGTENVLMAA 

       190        200        210        220        230        240 
VLAEGTTVLE NAAMEPEVTD LADCLIALGA QIEGAGTPRI TVQGVERLGG GHHAVLPDRI 

       250        260        270        280        290        300 
ETGTFLVAAA MTGGSVTVRR ARPDTLDAVL DKLTEAGATI TTTADSVTLD MHGKRPRAVN 

       310        320        330        340        350        360 
LTTAPYPAFP TDMQAQFMAL NCVADGVGVI NETIFENRFM HVNELLRLGA DIQVEGHTAI 

       370        380        390        400        410        420 
VRGAERLSGA PVMATDLRAS ASLILAGLVA DGDTTIDRIY HLDRGYENIE EKLGALGATI 


RRIA

« Hide

References

[1]"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. expand/collapse author list , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.
Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8004.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000050 Genomic DNA. Translation: AAY48387.1.
RefSeqYP_242407.1. NC_007086.1.

3D structure databases

ProteinModelPortalQ4UX36.
SMRQ4UX36. Positions 1-423.
ModBaseSearch...

Protein-protein interaction databases

STRING314565.XC_1318.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY48387; AAY48387; XC_1318.
GeneID3381777.
KEGGxcb:XC_1318.
PATRIC24064034. VBIXanCam24967_1424.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0766.
HOGENOMHOG000075602.
KOK00790.
OMASIWALAP.
ProtClustDBPRK09369.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURA_XANC8
AccessionPrimary (citable) accession number: Q4UX36
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2005
Last modified: May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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