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Q4UX36

- MURA_XANC8

UniProt

Q4UX36 - MURA_XANC8

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Protein

UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Gene
murA, XC_1318
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity.UniRule annotation

Catalytic activityi

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei122 – 1221Proton donor By similarity

GO - Molecular functioni

  1. UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
  4. regulation of cell shape Source: UniProtKB-KW
  5. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciXCAM314565:GCQG-1317-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC:2.5.1.7)
Alternative name(s):
Enoylpyruvate transferase
UDP-N-acetylglucosamine enolpyruvyl transferase
Short name:
EPT
Gene namesi
Name:murA
Ordered Locus Names:XC_1318
OrganismiXanthomonas campestris pv. campestris (strain 8004)
Taxonomic identifieri314565 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000000420: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424UDP-N-acetylglucosamine 1-carboxyvinyltransferaseUniRule annotationPRO_0000231301Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei122 – 12212-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Interactioni

Protein-protein interaction databases

STRINGi314565.XC_1318.

Structurei

3D structure databases

ProteinModelPortaliQ4UX36.
SMRiQ4UX36. Positions 1-423.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0766.
HOGENOMiHOG000075602.
KOiK00790.
OMAiHGLEQMG.
OrthoDBiEOG68M4GK.

Family and domain databases

Gene3Di3.65.10.10. 2 hits.
HAMAPiMF_00111. MurA.
InterProiIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERiPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamiPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMiSSF55205. SSF55205. 1 hit.
TIGRFAMsiTIGR01072. murA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UX36-1 [UniParc]FASTAAdd to Basket

« Hide

MAKIVVTGGQ ALHGEVHISG AKNAVLPILC ATLLADAPVE ISNVPHLHDV    50
ITTVKLLSEL GAEVTIDEGT LAKGRSILVD PRSVTHQIAP YELVKTMRAS 100
ILVLGPLLAR YGTAEVSLPG GCAIGSRPVD QHIKGLQALG ADISVENGYI 150
KATSNGRLKG GRYVFDMVSV TGTENVLMAA VLAEGTTVLE NAAMEPEVTD 200
LADCLIALGA QIEGAGTPRI TVQGVERLGG GHHAVLPDRI ETGTFLVAAA 250
MTGGSVTVRR ARPDTLDAVL DKLTEAGATI TTTADSVTLD MHGKRPRAVN 300
LTTAPYPAFP TDMQAQFMAL NCVADGVGVI NETIFENRFM HVNELLRLGA 350
DIQVEGHTAI VRGAERLSGA PVMATDLRAS ASLILAGLVA DGDTTIDRIY 400
HLDRGYENIE EKLGALGATI RRIA 424
Length:424
Mass (Da):44,445
Last modified:July 5, 2005 - v1
Checksum:i3E62A81EA5832EA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000050 Genomic DNA. Translation: AAY48387.1.
RefSeqiWP_011037922.1. NC_007086.1.
YP_242407.1. NC_007086.1.

Genome annotation databases

EnsemblBacteriaiAAY48387; AAY48387; XC_1318.
GeneIDi3381777.
KEGGixcb:XC_1318.
PATRICi24064034. VBIXanCam24967_1424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000050 Genomic DNA. Translation: AAY48387.1 .
RefSeqi WP_011037922.1. NC_007086.1.
YP_242407.1. NC_007086.1.

3D structure databases

ProteinModelPortali Q4UX36.
SMRi Q4UX36. Positions 1-423.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 314565.XC_1318.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY48387 ; AAY48387 ; XC_1318 .
GeneIDi 3381777.
KEGGi xcb:XC_1318.
PATRICi 24064034. VBIXanCam24967_1424.

Phylogenomic databases

eggNOGi COG0766.
HOGENOMi HOG000075602.
KOi K00790.
OMAi HGLEQMG.
OrthoDBi EOG68M4GK.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci XCAM314565:GCQG-1317-MONOMER.

Family and domain databases

Gene3Di 3.65.10.10. 2 hits.
HAMAPi MF_00111. MurA.
InterProi IPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view ]
PANTHERi PTHR21090:SF4. PTHR21090:SF4. 1 hit.
Pfami PF00275. EPSP_synthase. 1 hit.
[Graphical view ]
SUPFAMi SSF55205. SSF55205. 1 hit.
TIGRFAMsi TIGR01072. murA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
    Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L.
    , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.
    Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 8004.

Entry informationi

Entry nameiMURA_XANC8
AccessioniPrimary (citable) accession number: Q4UX36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2005
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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