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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Xanthomonas campestris pv. campestris (strain 8004)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. Fructose-bisphosphate aldolase (XC_0979)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei333Proton donorUniRule annotation1
Active sitei364UniRule annotation1
Active sitei473UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:XC_2465
OrganismiXanthomonas campestris pv. campestris (strain 8004)
Taxonomic identifieri314565 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000420 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807701 – 504Glucose-6-phosphate isomeraseAdd BLAST504

Interactioni

Protein-protein interaction databases

STRINGi314565.XC_2465.

Structurei

3D structure databases

ProteinModelPortaliQ4UTV8.
SMRiQ4UTV8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8. Bacteria.
COG0166. LUCA.
HOGENOMiHOG000261370.
KOiK01810.
OMAiTNSQHAF.
OrthoDBiPOG091H04C3.

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UTV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHTNGFDAL HAHAQRLRGA AIPALLAAEP QRPTQYARQV GPLYFNFARQ
60 70 80 90 100
KYDRAALDAL FAIARERDLA GAFQRLFRGE QVNVTEQRAA LHTALRGDLT
110 120 130 140 150
DAPVASDAYA TAAEVRQRVG ALIQQLEGTD VTDIVSVGIG GSDLGPRLVA
160 170 180 190 200
DALRAPSGAR FRVHFVSNVD GAAMQRTLAT LDPARTAGIL ISKTFGTQET
210 220 230 240 250
LLNGSILHAW LGGSERLYAV SANPERAAKA FDIAPGRVLP MWDWVGGRYS
260 270 280 290 300
LWSAVGFPIA LAIGFERFEQ LLDGAAQFDA HVLNTPLEEN VAVLHGLTAV
310 320 330 340 350
WNRNLLGSAT HAVMTYDQRL ALLPAYLQQL VMESLGKRVK LDGAAVDSDT
360 370 380 390 400
VAVWWGGAGT DVQHSFFQAL HQGTSVVPAD FIGTVHNDDP YAENHVALMA
410 420 430 440 450
NVLAQTEALA NGQDSSDPHR SYPGGRPSTV ILLDALTPQA LGALISMYEH
460 470 480 490 500
SVYVQSVMWG INAFDQFGVE LGKQLASQLL PALKGEAADV ADPVTRELLA

KLRG
Length:504
Mass (Da):54,176
Last modified:July 5, 2005 - v1
Checksum:iB3709DFCB1F3F46D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000050 Genomic DNA. Translation: AAY49515.1.
RefSeqiWP_011036944.1. NC_007086.1.

Genome annotation databases

EnsemblBacteriaiAAY49515; AAY49515; XC_2465.
KEGGixcb:XC_2465.

Similar proteinsi

Entry informationi

Entry nameiG6PI_XANC8
AccessioniPrimary (citable) accession number: Q4UTV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: July 5, 2005
Last modified: August 30, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families