Reviewed,
UniProtKB/Swiss-Prot Q4UT95 (3HAO_XANC8)
Last modified
June 16, 2009.
Version 27.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 3-hydroxyanthranilate 3,4-dioxygenase EC=1.13.11.6 Alternative name(s): 3-hydroxyanthranilic acid dioxygenase Short name=HAD 3-hydroxyanthranilate oxygenase Short name=3-HAO | ||
| Gene names |
| ||
| Organism | Xanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 314565 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas |
Protein attributes
| Sequence length | 176 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate By similarity. |
| Catalytic activity | 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. HAMAP MF_00825 |
| Cofactor | Binds 2 Fe2+ ions per subunit By similarity. |
| Subunit structure | Homodimer By similarity. |
| Sequence similarities | Belongs to the 3-HAO family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 3-hydroxyanthranilate 3,4-dioxygenase activity Inferred from electronic annotation. Source: HAMAP ferrous iron bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 176 | 176 | 3-hydroxyanthranilate 3,4-dioxygenase HAMAP MF_00825 | PRO_0000245481 | |||||
Sites | |||||||||
| Metal binding | 48 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 54 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 92 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 121 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 124 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 158 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 161 | 1 | Iron 2 By similarity | ||||||
| Binding site | 44 | 1 | Dioxygen By similarity | ||||||
| Binding site | 54 | 1 | Substrate By similarity | ||||||
| Binding site | 96 | 1 | Substrate By similarity | ||||||
| Binding site | 106 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | "Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris." Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. He C.Genome Res. 15:757-767(2005) [PubMed: 15899963] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000050 Genomic DNA. Translation: AAY49728.1. | |
| RefSeq | YP_243748.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3381213. |
| GenomeReviews | Gene locus XC_2679 in contig CP000050_GR. |
| KEGG | xcb:XC_2679. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q4UT95. |
| OMA | Q4UT95. RHSPQRP. |
Enzyme and pathway databases | |
| BioCyc | XCAM314565:XC_2679-MON. |
Family and domain databases | |
| HAMAP | MF_00825. [Tree] |
| InterPro | IPR010329. 3hydroanth_dOase. [Graphical view] |
| Pfam | PF06052. 3-HAO. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03037. anthran_nbaC. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | 3HAO_XANC8 | ||||||||
| Accession | Primary (citable) accession number: Q4UT95 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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