Q4UR00 (CAPP_XANC8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	XC_3479

Organism

Xanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP]

Taxonomic identifier

314565 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas › Xanthomonas campestris › Xanthomonas campestris pv. campestris

Protein attributes

Sequence length	904 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity. HAMAP-Rule MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 904	904	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_1000025602
Sites
	Active site	151	1	By similarity
	Active site	570	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4UR00 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: FD237097604D6A1F	FASTA	904	100,117
	10 20 30 40 50 60 MNEYRSSLVF ATPDVPLRDD VRRLGALVGD LLAEQVSADF LEEIERIRTT AIARRESDTP 70 80 90 100 110 120 PAGLLSLLEG REPRAAEALV RAFSTYFQVV NIAERVHRIR RRRDYQRSGT DTPQPEGLHD 130 140 150 160 170 180 ALRRLKAQGV TLDELSEWLP RIDVEPVFTA HPTEAVRRAL LEKEQLMVAS LVDNLDGMRT 190 200 210 220 230 240 PNERATDAAR FRMALTASWQ TADSSPVRPT VEDEREHVGF YLTQVLYRVI PVMYETLEHA 250 260 270 280 290 300 IEETYGSTLA LPRLLRFGTW VGGDMDGNPN VDAHTIAGTL DAQRRAVLDR YLNELWQLAS 310 320 330 340 350 360 LLSQSTTLVA VSPALSAQLE RYQALLPDAA ARSRPRHGDM PYRLLNDLMR ARLQATLDDA 370 380 390 400 410 420 DGAYAAPAEL EHDLQLILDS LQANKGLHAG WFAVRRLLWR VRSFGFHLAR LDVRQESSVH 430 440 450 460 470 480 ARAVADALGQ ADWDSQDATH RAGLLGPYAS GEQALPQVDD EGNARLDAVF AALADARTRH 490 500 510 520 530 540 GADALGSYII SMAHNRADVL TVLALARRGG LVDDAGAVPL DIVPLFETVD DLRGGTGTVQ 550 560 570 580 590 600 DLLADPVYRQ HLRARGDTQM VMLGYSDSGK DGGIAASRWG LQRAQVELLE AAAELGVRLT 610 620 630 640 650 660 FFHGRGGSIV RGGGKTTRAL DAAPRGSVDG RLRVTEQGEV IHRKYGIRAL ALRSLEQMTG 670 680 690 700 710 720 AVLLSSLRPR APEPREDAWR PVMDLVAERS TVAYRGFVGA PDFMQYFRLA TPIDVIERMT 730 740 750 760 770 780 LGSRPSRRLG QDAALSNLRA IPWVFAWSQA RAVIPGWYGV GSGLQAAVEA GHEDSLREMA 790 800 810 820 830 840 QDWPFFRTFL DDIAMVLSKG DLNIAELFSR LAGPLHARFF PRIRDELALT KHWVKTLLGQ 850 860 870 880 890 900 RSLLQHDPRL ALSIRLRNPY IDPISVLQVD LLQRWRATDG EDEELLRALV ACVNGVAQGV QNTG

References

[1]

"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris." Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C. Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 8004.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000050 Genomic DNA. Translation: AAY50523.1.
RefSeq	YP_244543.1. NC_007086.1.
3D structure databases
ProteinModelPortal	Q4UR00.
ModBase	Search...
Protein-protein interaction databases
STRING	314565.XC_3479.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAY50523; AAY50523; XC_3479.
GeneID	3379095.
KEGG	xcb:XC_3479.
PATRIC	24068647. VBIXanCam24967_3685.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Enzyme and pathway databases
BioCyc	XCAM314565:GCQG-3507-MONOMER.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_XANC8

Accession

Primary (citable) accession number: Q4UR00

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 5, 2005
Last modified:	May 29, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program