ID   XYLA2_XANC8             Reviewed;         446 AA.
AC   Q4UNZ4;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Xylose isomerase 2;
DE            EC=5.3.1.5;
GN   Name=xylA2; OrderedLocusNames=XC_4191;
OS   Xanthomonas campestris pv. campestris (strain 8004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=314565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15899963; DOI=10.1101/gr.3378705;
RA   Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q.,
RA   Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L.,
RA   Zeng S., Gu W.-Y., Lu G., Rong L., Tian Y., Yao Z., Fu G., Chen B.,
RA   Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.;
RT   "Comparative and functional genomic analyses of the pathogenicity of
RT   phytopathogen Xanthomonas campestris pv. campestris.";
RL   Genome Res. 15:757-767(2005).
CC   -!- CATALYTIC ACTIVITY: D-xylose = D-xylulose.
CC   -!- COFACTOR: Binds 2 magnesium ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the xylose isomerase family.
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DR   EMBL; CP000050; AAY51229.1; -; Genomic_DNA.
DR   RefSeq; YP_245249.1; -.
DR   GeneID; 3379809; -.
DR   GenomeReviews; CP000050_GR; XC_4191.
DR   KEGG; xcb:XC_4191; -.
DR   HOGENOM; Q4UNZ4; -.
DR   OMA; Q4UNZ4; FDATASE.
DR   BioCyc; XCAM314565:XC_4191-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009045; F:xylose isomerase activity; IEA:HAMAP.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:HAMAP.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP.
DR   HAMAP; MF_00455; -; 1.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   InterPro; IPR012307; Xyl_isomerase-typ_TIM-brl.
DR   InterPro; IPR013452; Xylose_isom_bac.
DR   InterPro; IPR001998; Xylose_isomerase.
DR   InterPro; IPR018115; Xylose_isomerase_AS.
DR   Gene3D; G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   PRINTS; PR00688; XYLOSISMRASE.
DR   TIGRFAMs; TIGR02630; xylose_isom_A; 1.
DR   PROSITE; PS51415; XYLOSE_ISOMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase;
KW   Magnesium; Metal-binding; Pentose shunt; Xylose metabolism.
FT   CHAIN         1    446       Xylose isomerase 2.
FT                                /FTId=PRO_0000236976.
FT   ACT_SITE    109    109       By similarity.
FT   ACT_SITE    112    112       By similarity.
FT   METAL       240    240       Magnesium 1 (By similarity).
FT   METAL       276    276       Magnesium 1 (By similarity).
FT   METAL       276    276       Magnesium 2 (By similarity).
FT   METAL       279    279       Magnesium 2 (By similarity).
FT   METAL       304    304       Magnesium 1 (By similarity).
FT   METAL       315    315       Magnesium 2 (By similarity).
FT   METAL       317    317       Magnesium 2 (By similarity).
FT   METAL       347    347       Magnesium 1 (By similarity).
SQ   SEQUENCE   446 AA;  48792 MW;  515F13FDF24B6C67 CRC64;
     MSNTVFIGAK EYFPGIGKIG FEGRDSDNPL AFKVYDANKQ VAGKTMAEHL RFAVAYWHSF
     CGNGADPFGP GTRAYPWDVG NTALARAEAK SDAAFEFFTK LGVPYYCFHD IDLAPDADDI
     GEYENNLKHM VGIAKQRQAD TGVKLLWGTA NLFSHPRYMN GASTNPDFNV VARAAVQVKA
     AIDATVELGG ENYVFWGGRE GYACLHNTQM KREQDNMARF LTLARDYGRA IGFKGNFLIE
     PKPMEPMKHQ YDFDSATVIG FLRQHGLDQD FKLNIEANHA TLSGHSFEHD LQVASDAGLL
     GSIDANRGNP QNGWDTDQFP TDLYDTVGAM LVVLRQGGLA PGGLNFDAKV RRESSDPQDL
     FLAHIGGMDA FARGLEVADA LLTSSPLETW RAQRYASFDS GAGADFANGT STLADLATYA
     AGKGEPTQLS GRQEAYENLI NQYLTR
//