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Q4UNV0 (KITH_XANC8) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Thymidine kinase

EC=2.7.1.21
Gene names
Name:tdk
Ordered Locus Names:XC_4235
OrganismXanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP]
Taxonomic identifier314565 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family.

Ontologies

Keywords
   Biological processDNA synthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 209209Thymidine kinase HAMAP-Rule MF_00124
PRO_0000242812

Regions

Nucleotide binding9 – 168ATP By similarity
Nucleotide binding88 – 914ATP By similarity

Sites

Active site891Proton acceptor Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UNV0 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: C725FFC963414B19

FASTA20923,271
        10         20         30         40         50         60 
MAKLYFYYSA MNAGKTTTLL QSAHNYRERG MRTSILTPKL DHRAGSGVVA SRIGLRADGQ 

        70         80         90        100        110        120 
TFDRQTELLQ LIERDIAAHG PLHCVLVDEA QFLSSAQVWQ LSEVVDRLRI PVLCYGLRTD 

       130        140        150        160        170        180 
FRGELFEGSQ FLLAWADELE EIKTICHSGS KATMTVRVDA QGHAVQDGPQ VEIGGNERYV 

       190        200 
SVSRAEFKKI MRGEGRIDPL QIALPLPPA 

« Hide

References

[1]"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. expand/collapse author list , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.
Genome Res. 15:757-767(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8004.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000050 Genomic DNA. Translation: AAY51273.1.
RefSeqYP_245293.1. NC_007086.1.

3D structure databases

ProteinModelPortalQ4UNV0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING314565.XC_4235.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY51273; AAY51273; XC_4235.
GeneID3379853.
KEGGxcb:XC_4235.
PATRIC24070279. VBIXanCam24967_4491.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMARTICHCG.
OrthoDBEOG69D3J2.
ProtClustDBPRK04296.

Enzyme and pathway databases

BioCycXCAM314565:GCQG-4266-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKITH_XANC8
AccessionPrimary (citable) accession number: Q4UNV0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2005
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families