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Q4UNT2 (Q4UNT2_XANC8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:folE HAMAP MF_00223
Ordered Locus Names:XC_4253
OrganismXanthomonas campestris pv. campestris (strain 8004) [Complete proteome] [HAMAP]
Taxonomic identifier314565 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding961Zinc By similarity HAMAP MF_00223
Metal binding991Zinc By similarity HAMAP MF_00223
Metal binding1671Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q4UNT2 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: CC848275843577D5

FASTA20923,587
        10         20         30         40         50         60 
MHAPFGCMRM SQSDQPDSSV TQAQAEEAVR TLLRWAGEDP AREGLLDTPR RVAEAYGDWF 

        70         80         90        100        110        120 
SGYREEPRAY LERTFEEVAG YDELIVLRDI SYESHCEHHM APIIGKVHVG YLPRGKVVGI 

       130        140        150        160        170        180 
SKLARVVESY ARRFQVQEKM TAQIAQCIQD VLQPRGVGVV VEGAHECMTT RGIHKRGVSM 

       190        200 
VTSKMLGSFR EDARTRAEFL QFIEVGGKR

« Hide

References

[1]"Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris."
Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q., Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S., Gu W.-Y., Lu G., Rong L. expand/collapse author list , Tian Y., Yao Z., Fu G., Chen B., Fang R., Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.
Genome Res. 15:757-767(2005) [PubMed: 15899963] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000050 Genomic DNA. Translation: AAY51291.1.
RefSeqYP_245311.1. NC_007086.1.

3D structure databases

ProteinModelPortalQ4UNT2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4UNT2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3379871.
GenomeReviewsGene locus XC_4253 in contig CP000050_GR.
KEGGxcb:XC_4253.
PATRIC24070338. VBIXanCam24967_4515.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMAEPREYLE.
PhylomeDBQ4UNT2.
ProtClustDBPRK09347.

Enzyme and pathway databases

BioCycXCAM314565:XC_4253-MONOMER.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4UNT2_XANC8
AccessionPrimary (citable) accession number: Q4UNT2
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info