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Protein

Putative pyruvate, phosphate dikinase regulatory protein

Gene

RF_0001

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

Catalytic activityi

ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate.UniRule annotation
[Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi149 – 156ADPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandNucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pyruvate, phosphate dikinase regulatory proteinUniRule annotation (EC:2.7.11.32UniRule annotation, EC:2.7.4.27UniRule annotation)
Short name:
PPDK regulatory proteinUniRule annotation
Gene namesi
Ordered Locus Names:RF_0001
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001967021 – 273Putative pyruvate, phosphate dikinase regulatory proteinAdd BLAST273

Proteomic databases

PRIDEiQ4UNK5

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0001

Structurei

3D structure databases

SMRiQ4UNK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CF9 Bacteria
COG1806 LUCA
HOGENOMiHOG000218052
KOiK09773
OMAiTSKTPTC
OrthoDBiPOG091H00ZQ

Family and domain databases

HAMAPiMF_00921 PDRP, 1 hit
InterProiView protein in InterPro
IPR005177 Kinase-pyrophosphorylase
IPR026565 PPDK_reg
PANTHERiPTHR31756 PTHR31756, 1 hit
PfamiView protein in Pfam
PF03618 Kinase-PPPase, 1 hit

Sequencei

Sequence statusi: Complete.

Q4UNK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKLIIHLVS DSSVQTAKYA ANSAFAQFTS IKPKLYHWPM IRNLELLNEV
60 70 80 90 100
LSKIESKHGL VLYTIADQEL RKALTKFCYE LKIPCISVIG KIIKEISVFS
110 120 130 140 150
GIEIEKEQNY NYKFDKTYFD TLNAIDYAIR HDDGQMLNEL SEADIILIGP
160 170 180 190 200
SRTSKTPTSV FLAYNGLKAA NIPYVYNCPF PDFIEKDIDL LVVGLVINPN
210 220 230 240 250
RLIEIREARL NLLQINENKS YTDFNIVQKE CLEVRKICDQ RNWPVIDVST
260 270
RSIEETAALI MRIYYNRKNK YNK
Length:273
Mass (Da):31,559
Last modified:July 5, 2005 - v1
Checksum:iDC8EB17985A8E469
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA Translation: AAY60852.1
RefSeqiWP_011270358.1, NC_007109.1

Genome annotation databases

EnsemblBacteriaiAAY60852; AAY60852; RF_0001
KEGGirfe:RF_0001

Similar proteinsi

Entry informationi

Entry nameiPDRP_RICFE
AccessioniPrimary (citable) accession number: Q4UNK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: July 5, 2005
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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