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Q4UNK5

- PDRP_RICFE

UniProt

Q4UNK5 - PDRP_RICFE

Protein

Putative pyruvate, phosphate dikinase regulatory protein

Gene

RF_0001

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

    Catalytic activityi

    ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate.UniRule annotation
    [Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi149 – 1568ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-1-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative pyruvate, phosphate dikinase regulatory proteinUniRule annotation (EC:2.7.11.32UniRule annotation, EC:2.7.4.27UniRule annotation)
    Short name:
    PPDK regulatory proteinUniRule annotation
    Gene namesi
    Ordered Locus Names:RF_0001
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Putative pyruvate, phosphate dikinase regulatory proteinPRO_0000196702Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0001.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1806.
    HOGENOMiHOG000218052.
    KOiK09773.
    OMAiSFFHLHL.
    OrthoDBiEOG6KHG2N.

    Family and domain databases

    HAMAPiMF_00921. PDRP.
    InterProiIPR005177. Kinase-pyrophosphorylase.
    IPR026565. PPDK_reg.
    [Graphical view]
    PfamiPF03618. Kinase-PPPase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UNK5-1 [UniParc]FASTAAdd to Basket

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    MTKLIIHLVS DSSVQTAKYA ANSAFAQFTS IKPKLYHWPM IRNLELLNEV    50
    LSKIESKHGL VLYTIADQEL RKALTKFCYE LKIPCISVIG KIIKEISVFS 100
    GIEIEKEQNY NYKFDKTYFD TLNAIDYAIR HDDGQMLNEL SEADIILIGP 150
    SRTSKTPTSV FLAYNGLKAA NIPYVYNCPF PDFIEKDIDL LVVGLVINPN 200
    RLIEIREARL NLLQINENKS YTDFNIVQKE CLEVRKICDQ RNWPVIDVST 250
    RSIEETAALI MRIYYNRKNK YNK 273
    Length:273
    Mass (Da):31,559
    Last modified:July 5, 2005 - v1
    Checksum:iDC8EB17985A8E469
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60852.1.
    RefSeqiYP_246017.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY60852; AAY60852; RF_0001.
    GeneIDi3401264.
    KEGGirfe:RF_0001.
    PATRICi17890308. VBIRicFel64634_0001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60852.1 .
    RefSeqi YP_246017.1. NC_007109.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY60852 ; AAY60852 ; RF_0001 .
    GeneIDi 3401264.
    KEGGi rfe:RF_0001.
    PATRICi 17890308. VBIRicFel64634_0001.

    Phylogenomic databases

    eggNOGi COG1806.
    HOGENOMi HOG000218052.
    KOi K09773.
    OMAi SFFHLHL.
    OrthoDBi EOG6KHG2N.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-1-MONOMER.

    Family and domain databases

    HAMAPi MF_00921. PDRP.
    InterProi IPR005177. Kinase-pyrophosphorylase.
    IPR026565. PPDK_reg.
    [Graphical view ]
    Pfami PF03618. Kinase-PPPase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiPDRP_RICFE
    AccessioniPrimary (citable) accession number: Q4UNK5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 10, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3