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Q4UNK5 (PDRP_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative pyruvate, phosphate dikinase regulatory protein
Short name=PPDK regulatory protein
EC=2.7.11.32
EC=2.7.4.27
Gene names
Ordered Locus Names:RF_0001
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group ›

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation By similarity. HAMAP-Rule MF_00921

Catalytic activity

ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate. HAMAP-Rule MF_00921

[Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate. HAMAP-Rule MF_00921

Sequence similarities

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 273273Putative pyruvate, phosphate dikinase regulatory protein HAMAP-Rule MF_00921
PRO_0000196702

Regions

Nucleotide binding149 – 1568ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UNK5 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: DC8EB17985A8E469

FASTA27331,559
        10         20         30         40         50         60 
MTKLIIHLVS DSSVQTAKYA ANSAFAQFTS IKPKLYHWPM IRNLELLNEV LSKIESKHGL 

        70         80         90        100        110        120 
VLYTIADQEL RKALTKFCYE LKIPCISVIG KIIKEISVFS GIEIEKEQNY NYKFDKTYFD 

       130        140        150        160        170        180 
TLNAIDYAIR HDDGQMLNEL SEADIILIGP SRTSKTPTSV FLAYNGLKAA NIPYVYNCPF 

       190        200        210        220        230        240 
PDFIEKDIDL LVVGLVINPN RLIEIREARL NLLQINENKS YTDFNIVQKE CLEVRKICDQ 

       250        260        270 
RNWPVIDVST RSIEETAALI MRIYYNRKNK YNK

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References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000053 Genomic DNA. Translation: AAY60852.1.
RefSeqYP_246017.1. NC_007109.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING315456.RF_0001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY60852; AAY60852; RF_0001.
GeneID3401264.
KEGGrfe:RF_0001.
PATRIC17890308. VBIRicFel64634_0001.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1806.
HOGENOMHOG000218052.
KOK09773.
OMALAHKGYK.
ProtClustDBPRK05339.

Family and domain databases

HAMAPMF_00921. PDRP.
InterProIPR005177. Kinase-pyrophosphorylase.
IPR026565. PPDK_reg.
[Graphical view]
PfamPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePDRP_RICFE
AccessionPrimary (citable) accession number: Q4UNK5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: July 5, 2005
Last modified: May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

SIMILARITY comments

Index of protein domains and families

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