Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4UNH9

- ATPL_RICFE

UniProt

Q4UNH9 - ATPL_RICFE

Protein

ATP synthase subunit c

Gene

atpE

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation.UniRule annotation
    Key component of the F0 channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F1 delta and epsilon subunits.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei58 – 581Reversibly protonated during proton transportUniRule annotation

    GO - Molecular functioni

    1. hydrogen ion transmembrane transporter activity Source: InterPro
    2. lipid binding Source: UniProtKB-KW

    GO - Biological processi

    1. ATP hydrolysis coupled proton transport Source: InterPro
    2. ATP synthesis coupled proton transport Source: InterPro

    Keywords - Biological processi

    ATP synthesis, Hydrogen ion transport, Ion transport, Transport

    Keywords - Ligandi

    Lipid-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-31-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP synthase subunit cUniRule annotation
    Alternative name(s):
    ATP synthase F(0) sector subunit cUniRule annotation
    F-type ATPase subunit cUniRule annotation
    Short name:
    F-ATPase subunit cUniRule annotation
    Lipid-binding proteinUniRule annotation
    Gene namesi
    Name:atpEUniRule annotation
    Ordered Locus Names:RF_0029
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    3. proton-transporting ATP synthase complex, coupling factor F(o) Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, CF(0), Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7474ATP synthase subunit cPRO_0000288729Add
    BLAST

    Interactioni

    Subunit structurei

    F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

    Protein-protein interaction databases

    STRINGi315456.RF_0029.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UNH9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2821HelicalUniRule annotationAdd
    BLAST
    Transmembranei52 – 7221HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATPase C chain family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0636.
    HOGENOMiHOG000235245.
    KOiK02110.
    OMAiGIACLGM.
    OrthoDBiEOG68H8G3.

    Family and domain databases

    Gene3Di1.20.20.10. 1 hit.
    HAMAPiMF_01396. ATP_synth_c_bact.
    InterProiIPR000454. ATPase_F0-cplx_csu.
    IPR020537. ATPase_F0-cplx_csu_DDCD_BS.
    IPR002379. ATPase_proteolipid_c_like_dom.
    [Graphical view]
    PfamiPF00137. ATP-synt_C. 1 hit.
    [Graphical view]
    PRINTSiPR00124. ATPASEC.
    SUPFAMiSSF81333. SSF81333. 1 hit.
    PROSITEiPS00605. ATPASE_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UNH9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDMVSLKFIG IGLMAIGMYG AALGVSNIFS SLLSSIARNP SAAENLQRMA   50
    LIGAGLAEAM GLFSFVIAML LIFS 74
    Length:74
    Mass (Da):7,686
    Last modified:July 5, 2005 - v1
    Checksum:i43844F903C4A0C65
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60880.1.
    RefSeqiYP_246045.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY60880; AAY60880; RF_0029.
    GeneIDi3401255.
    KEGGirfe:RF_0029.
    PATRICi17890382. VBIRicFel64634_0036.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60880.1 .
    RefSeqi YP_246045.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UNH9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0029.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY60880 ; AAY60880 ; RF_0029 .
    GeneIDi 3401255.
    KEGGi rfe:RF_0029.
    PATRICi 17890382. VBIRicFel64634_0036.

    Phylogenomic databases

    eggNOGi COG0636.
    HOGENOMi HOG000235245.
    KOi K02110.
    OMAi GIACLGM.
    OrthoDBi EOG68H8G3.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-31-MONOMER.

    Family and domain databases

    Gene3Di 1.20.20.10. 1 hit.
    HAMAPi MF_01396. ATP_synth_c_bact.
    InterProi IPR000454. ATPase_F0-cplx_csu.
    IPR020537. ATPase_F0-cplx_csu_DDCD_BS.
    IPR002379. ATPase_proteolipid_c_like_dom.
    [Graphical view ]
    Pfami PF00137. ATP-synt_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00124. ATPASEC.
    SUPFAMi SSF81333. SSF81333. 1 hit.
    PROSITEi PS00605. ATPASE_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiATPL_RICFE
    AccessioniPrimary (citable) accession number: Q4UNH9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3