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Protein

Putative protein-disulfide oxidoreductase RF_0032

Gene

RF_0032

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for disulfide bond formation in some proteins.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-34-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein-disulfide oxidoreductase RF_0032 (EC:1.8.-.-)
Gene namesi
Ordered Locus Names:RF_0032
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000025999019 – 278Putative protein-disulfide oxidoreductase RF_0032Add BLAST260

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi119 ↔ 122Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0032.

Structurei

3D structure databases

ProteinModelPortaliQ4UNH3.
SMRiQ4UNH3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 266ThioredoxinPROSITE-ProRule annotationAdd BLAST190

Sequence similaritiesi

Belongs to the thioredoxin family. DsbA subfamily.Curated

Keywords - Domaini

Redox-active center, Signal

Phylogenomic databases

eggNOGiENOG4108R9S. Bacteria.
COG1651. LUCA.
HOGENOMiHOG000272918.
OMAiNHEEKQI.
OrthoDBiPOG091H08FY.

Family and domain databases

InterProiView protein in InterPro
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
PfamiView protein in Pfam
PF13462. Thioredoxin_4. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q4UNH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSIFIVPIF LLFLSSCSEE KTQNKNQEEK QIIVQETLQN NNTSQEINQE
60 70 80 90 100
AVNSENAAES IVPANDNNQT DEVSTPPSQE QKNPEIKPVK VTFKVDDNDM
110 120 130 140 150
VLGNKKSNVI VVEYFSPTCP HCAYYHQTIF PELKKKYIDT NKIAYVVREF
160 170 180 190 200
IATKQDLDAA ILARCKGDIN SFVQFHNIIL QQQDKWAYSN KYRELLTDIG
210 220 230 240 250
QLGGVPPEEY KQCLNSDKIT ETLIANTNFV ANAPKFIGTP SFFVNGVQTG
260 270
NYSIDSISTA VDKALEEQKE KAKNEMSL
Length:278
Mass (Da):31,414
Last modified:July 5, 2005 - v1
Checksum:i52818097296CCF18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY60883.1.
RefSeqiWP_011270388.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60883; AAY60883; RF_0032.
KEGGirfe:RF_0032.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiDSB_RICFE
AccessioniPrimary (citable) accession number: Q4UNH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: July 5, 2005
Last modified: June 7, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families