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Q4UNH3 (DSB_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative protein-disulfide oxidoreductase RF_0032

EC=1.8.-.-
Gene names
Ordered Locus Names:RF_0032
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be required for disulfide bond formation in some proteins By similarity.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the thioredoxin family. DsbA subfamily.

Contains 1 thioredoxin domain.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainRedox-active center
Signal
   Molecular functionOxidoreductase
   PTMDisulfide bond
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcell redox homeostasis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 278260Putative protein-disulfide oxidoreductase RF_0032
PRO_0000259990

Regions

Domain77 – 266190Thioredoxin

Amino acid modifications

Disulfide bond119 ↔ 122Redox-active Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UNH3 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 52818097296CCF18

FASTA27831,414
        10         20         30         40         50         60 
MRSIFIVPIF LLFLSSCSEE KTQNKNQEEK QIIVQETLQN NNTSQEINQE AVNSENAAES 

        70         80         90        100        110        120 
IVPANDNNQT DEVSTPPSQE QKNPEIKPVK VTFKVDDNDM VLGNKKSNVI VVEYFSPTCP 

       130        140        150        160        170        180 
HCAYYHQTIF PELKKKYIDT NKIAYVVREF IATKQDLDAA ILARCKGDIN SFVQFHNIIL 

       190        200        210        220        230        240 
QQQDKWAYSN KYRELLTDIG QLGGVPPEEY KQCLNSDKIT ETLIANTNFV ANAPKFIGTP 

       250        260        270 
SFFVNGVQTG NYSIDSISTA VDKALEEQKE KAKNEMSL 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY60883.1.
RefSeqYP_246048.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UNH3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0032.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY60883; AAY60883; RF_0032.
GeneID3401258.
KEGGrfe:RF_0032.
PATRIC17890388. VBIRicFel64634_0039.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1651.
HOGENOMHOG000272918.
OMAMRSIFIV.
OrthoDBEOG6TR0CZ.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-34-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view]
PfamPF13462. Thioredoxin_4. 1 hit.
[Graphical view]
SUPFAMSSF52833. SSF52833. 1 hit.
PROSITEPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDSB_RICFE
AccessionPrimary (citable) accession number: Q4UNH3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names