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Q4UNH3

- DSB_RICFE

UniProt

Q4UNH3 - DSB_RICFE

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Protein

Putative protein-disulfide oxidoreductase RF_0032

Gene

RF_0032

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May be required for disulfide bond formation in some proteins.By similarity

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-34-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein-disulfide oxidoreductase RF_0032 (EC:1.8.-.-)
Gene namesi
Ordered Locus Names:RF_0032
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Periplasm By similarity

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 278260Putative protein-disulfide oxidoreductase RF_0032PRO_0000259990Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi119 ↔ 122Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0032.

Structurei

3D structure databases

ProteinModelPortaliQ4UNH3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini77 – 266190ThioredoxinPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the thioredoxin family. DsbA subfamily.Curated
Contains 1 thioredoxin domain.PROSITE-ProRule annotation

Keywords - Domaini

Redox-active center, Signal

Phylogenomic databases

eggNOGiCOG1651.
HOGENOMiHOG000272918.
OMAiMRSIFIV.
OrthoDBiEOG6TR0CZ.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view]
PfamiPF13462. Thioredoxin_4. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q4UNH3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRSIFIVPIF LLFLSSCSEE KTQNKNQEEK QIIVQETLQN NNTSQEINQE
60 70 80 90 100
AVNSENAAES IVPANDNNQT DEVSTPPSQE QKNPEIKPVK VTFKVDDNDM
110 120 130 140 150
VLGNKKSNVI VVEYFSPTCP HCAYYHQTIF PELKKKYIDT NKIAYVVREF
160 170 180 190 200
IATKQDLDAA ILARCKGDIN SFVQFHNIIL QQQDKWAYSN KYRELLTDIG
210 220 230 240 250
QLGGVPPEEY KQCLNSDKIT ETLIANTNFV ANAPKFIGTP SFFVNGVQTG
260 270
NYSIDSISTA VDKALEEQKE KAKNEMSL
Length:278
Mass (Da):31,414
Last modified:July 5, 2005 - v1
Checksum:i52818097296CCF18
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60883.1.
RefSeqiYP_246048.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60883; AAY60883; RF_0032.
GeneIDi3401258.
KEGGirfe:RF_0032.
PATRICi17890388. VBIRicFel64634_0039.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60883.1 .
RefSeqi YP_246048.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UNH3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0032.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY60883 ; AAY60883 ; RF_0032 .
GeneIDi 3401258.
KEGGi rfe:RF_0032.
PATRICi 17890388. VBIRicFel64634_0039.

Phylogenomic databases

eggNOGi COG1651.
HOGENOMi HOG000272918.
OMAi MRSIFIV.
OrthoDBi EOG6TR0CZ.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-34-MONOMER.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view ]
Pfami PF13462. Thioredoxin_4. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiDSB_RICFE
AccessioniPrimary (citable) accession number: Q4UNH3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3