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Q4UNH3

- DSB_RICFE

UniProt

Q4UNH3 - DSB_RICFE

Protein

Putative protein-disulfide oxidoreductase RF_0032

Gene

RF_0032

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    May be required for disulfide bond formation in some proteins.By similarity

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    GO - Biological processi

    1. cell redox homeostasis Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-34-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative protein-disulfide oxidoreductase RF_0032 (EC:1.8.-.-)
    Gene namesi
    Ordered Locus Names:RF_0032
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Periplasm By similarity

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 278260Putative protein-disulfide oxidoreductase RF_0032PRO_0000259990Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi119 ↔ 122Redox-activePROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0032.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UNH3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini77 – 266190ThioredoxinPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the thioredoxin family. DsbA subfamily.Curated
    Contains 1 thioredoxin domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Redox-active center, Signal

    Phylogenomic databases

    eggNOGiCOG1651.
    HOGENOMiHOG000272918.
    OMAiMRSIFIV.
    OrthoDBiEOG6TR0CZ.

    Family and domain databases

    Gene3Di3.40.30.10. 1 hit.
    InterProiIPR012336. Thioredoxin-like_fold.
    IPR017937. Thioredoxin_CS.
    [Graphical view]
    PfamiPF13462. Thioredoxin_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF52833. SSF52833. 1 hit.
    PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
    PS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q4UNH3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSIFIVPIF LLFLSSCSEE KTQNKNQEEK QIIVQETLQN NNTSQEINQE    50
    AVNSENAAES IVPANDNNQT DEVSTPPSQE QKNPEIKPVK VTFKVDDNDM 100
    VLGNKKSNVI VVEYFSPTCP HCAYYHQTIF PELKKKYIDT NKIAYVVREF 150
    IATKQDLDAA ILARCKGDIN SFVQFHNIIL QQQDKWAYSN KYRELLTDIG 200
    QLGGVPPEEY KQCLNSDKIT ETLIANTNFV ANAPKFIGTP SFFVNGVQTG 250
    NYSIDSISTA VDKALEEQKE KAKNEMSL 278
    Length:278
    Mass (Da):31,414
    Last modified:July 5, 2005 - v1
    Checksum:i52818097296CCF18
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60883.1.
    RefSeqiYP_246048.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY60883; AAY60883; RF_0032.
    GeneIDi3401258.
    KEGGirfe:RF_0032.
    PATRICi17890388. VBIRicFel64634_0039.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60883.1 .
    RefSeqi YP_246048.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UNH3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0032.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY60883 ; AAY60883 ; RF_0032 .
    GeneIDi 3401258.
    KEGGi rfe:RF_0032.
    PATRICi 17890388. VBIRicFel64634_0039.

    Phylogenomic databases

    eggNOGi COG1651.
    HOGENOMi HOG000272918.
    OMAi MRSIFIV.
    OrthoDBi EOG6TR0CZ.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-34-MONOMER.

    Family and domain databases

    Gene3Di 3.40.30.10. 1 hit.
    InterProi IPR012336. Thioredoxin-like_fold.
    IPR017937. Thioredoxin_CS.
    [Graphical view ]
    Pfami PF13462. Thioredoxin_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52833. SSF52833. 1 hit.
    PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
    PS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiDSB_RICFE
    AccessioniPrimary (citable) accession number: Q4UNH3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 14, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3