Q4UNG8 (RECF_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	RF_0035

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity. HAMAP MF_00365
Subcellular location	Cytoplasm By similarity HAMAP MF_00365.
Sequence similarities	Belongs to the recF family.
Sequence caution	The sequence AAY60886.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW SOS response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW single-stranded DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 364	364	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000236138
Regions
	Nucleotide binding	33 – 40	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q4UNG8 [UniParc]. Last modified May 16, 2006. Version 2. Checksum: CC7E4DA8672E61EE	FASTA	364	41,857
	10 20 30 40 50 60 MKNIFLHSLT LENYRNFKNL ELKTDNTPII LIGENGSGKT NILEAISLFY PGRGLRSAKL 70 80 90 100 110 120 ADICKASEDQ CLVKALLQSK LGLAEFTTQF KRSSNRRITE YNESKIANNE LSKFTSMVWL 130 140 150 160 170 180 TPQMEGIFTS GSSDRRKFLD RIVYNFDSKH AELVSKYEYY MYERNKILAE DIRDDNWLKI 190 200 210 220 230 240 IEEKMADMSS HIANNRLKTL EFMQQAIDEL ENEFPKADLS IDGIVEQKIL DGKENIVNFI 250 260 270 280 290 300 TAELYQTRSK DKLLGRTSFG VHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEMNYA 310 320 330 340 350 360 IKLTKIAPIL LLDEVFVHLD DKRRGYLIEF FTGLNMQLWV TATDLEGIEN FANKAQLIKL PIIL

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY60886.1. Different initiation.
RefSeq	YP_246051.1. NC_007109.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3401261.
GenomeReviews	Gene locus RF_0035 in contig CP000053_GR.
KEGG	rfe:RF_0035.
NMPDR	fig|315456.3.peg.517.
PATRIC	17890394. VBIRicFel64634_0042.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645124.
OMA	GQQRTLV.
ProtClustDB	PRK00064.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0035-MONOMER.
Family and domain databases
HAMAP	MF_00365. RecF. [Tree]
InterPro	IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR003395. RecF/RecN/SMC. [Graphical view]
KO	K03629.
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00611. Recf. 1 hit.
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_RICFE

Accession

Primary (citable) accession number: Q4UNG8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program