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Q4UND3 (AAT_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate aminotransferase

Short name=AspAT
EC=2.6.1.1
Alternative name(s):
Transaminase A
Gene names
Name:aatA
Ordered Locus Names:RF_0074
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 409409Aspartate aminotransferase
PRO_0000273125

Sites

Binding site391Aspartate; via amide nitrogen By similarity
Binding site1251Aspartate By similarity
Binding site1751Aspartate By similarity
Binding site3751Aspartate By similarity

Amino acid modifications

Modified residue2391N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UND3 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 2A7CD6AC91F68343

FASTA40945,448
        10         20         30         40         50         60 
MSIISTRLNS IKPSPTLAVV KKTLELKKAG VDIIALGAGE PDFDTPDNIK EAAIKAIKDG 

        70         80         90        100        110        120 
FTKYTNVEGM PLLKQAIKDK FKRENNIDYE LDEIIVSTGG KQVIYNLFMA SLDKGDKVII 

       130        140        150        160        170        180 
PAPYWVSYPD MVALSTGTPV FVNCGIENNF KLSAEALERS ITDKTKWLII NSPSNPTGAS 

       190        200        210        220        230        240 
YNFEELENIA KVLRKYPHVN VMSDDIYEHI TFDDFKFYTL AQIAPDLKER IFTVNGVSKA 

       250        260        270        280        290        300 
YSMTGWRIGY GVGSKALIKA MTIIQSQSTS NPCSISQMAA IESLNGPQDY IKPNALNFQK 

       310        320        330        340        350        360 
KRDLALSILK RVKYFECYKP EGAFYLFVKC DKIFGHKTKS GKIIANSNDF AEYLLEEAKV 

       370        380        390        400 
AVVPGIAFGL EGYFRISYAT SMEELEEACI RIERACGSIS IKSSLRGDA 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY60925.1.
RefSeqYP_246090.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UND3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0074.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY60925; AAY60925; RF_0074.
GeneID3400304.
KEGGrfe:RF_0074.
PATRIC17890482. VBIRicFel64634_0085.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0436.
HOGENOMHOG000223062.
KOK00812.
OMARCILING.
OrthoDBEOG6RRKNS.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-77-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAAT_RICFE
AccessionPrimary (citable) accession number: Q4UND3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names