Reviewed,
UniProtKB/Swiss-Prot Q4UND3 (AAT_RICFE)
Last modified
February 9, 2010.
Version 34.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Aspartate aminotransferase Short name=AspAT EC=2.6.1.1 Alternative name(s): Transaminase A | ||||
| Gene names |
| ||||
| Organism | Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 42862 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group |
Protein attributes
| Sequence length | 409 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. |
| Cofactor | Pyridoxal phosphate By similarity. |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | Pyridoxal phosphate |
| Molecular function | Aminotransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro L-aspartate:2-oxoglutarate aminotransferase activityInferred from electronic annotation. Source: EC pyridoxal phosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 409 | 409 | Aspartate aminotransferase | PRO_0000273125 | |||||
Sites | |||||||||
| Binding site | 39 | 1 | Aspartate; via amide nitrogen By similarity | ||||||
| Binding site | 125 | 1 | Aspartate By similarity | ||||||
| Binding site | 175 | 1 | Aspartate By similarity | ||||||
| Binding site | 375 | 1 | Aspartate By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 239 | 1 | N6-(pyridoxal phosphate)lysine By similarity | ||||||
Sequences
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References
| [1] | "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000053 Genomic DNA. Translation: AAY60925.1. |
| RefSeq | YP_246090.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1BKG based on UniProtKB Q56232. |
| SMR | Q4UND3. Positions 1-395. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3400304. |
| GenomeReviews | Gene locus RF_0074 in contig CP000053_GR. |
| KEGG | rfe:RF_0074. |
| NMPDR | fig|315456.3.peg.556. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG645860. |
| OMA | KRENNID. |
Enzyme and pathway databases | |
| BioCyc | RFEL315456:RF_0074-MONOMER. |
| BRENDA | 2.6.1.1. 297363. |
Family and domain databases | |
| InterPro | IPR001176. ACC_synthase. IPR004839. Aminotransferase_I/II. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view] |
| Gene3D | G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. |
| Pfam | PF00155. Aminotran_1_2. 1 hit. [Graphical view] |
| PRINTS | PR00753. ACCSYNTHASE. |
| PROSITE | PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AAT_RICFE | ||||||||
| Accession | Primary (citable) accession number: Q4UND3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Rickettsia felis (Rickettsia azadi) Rickettsia felis (strain URRWXCal2): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


