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Q4UN94

- KDSA_RICFE

UniProt

Q4UN94 - KDSA_RICFE

Protein

2-dehydro-3-deoxyphosphooctonate aldolase

Gene

kdsA

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-deoxy-8-phosphooctulonate synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-117-MONOMER.
    UniPathwayiUPA00030.
    UPA00357; UER00474.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)
    Alternative name(s):
    3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation
    KDO-8-phosphate synthaseUniRule annotation
    Short name:
    KDO 8-P synthaseUniRule annotation
    Short name:
    KDOPSUniRule annotation
    Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation
    Gene namesi
    Name:kdsAUniRule annotation
    Ordered Locus Names:RF_0113
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2742742-dehydro-3-deoxyphosphooctonate aldolasePRO_0000277912Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0113.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UN94.
    SMRiQ4UN94. Positions 17-271.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KdsA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2877.
    HOGENOMiHOG000023021.
    KOiK01627.
    OMAiMESREHA.
    OrthoDBiEOG680X4R.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00056. KDO8P_synth.
    InterProiIPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view]
    PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
    PfamiPF00793. DAHP_synth_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4UN94-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKVVKLNNI KIGNDLPFVL IAGPCQIEGK DHALFMAEKL VKLTSKLEIP    50
    FIYKSSFDKA NRTSVNGIRG LGIEKGLEIL SKVKSEFDCP IVTDVHSESQ 100
    CTETAEIADI LQIPAFLCRQ TDLLQAAAKT GKIVKVKKGQ FLAPWDMKNV 150
    QTKLEAFGVK DILFTERGAC FGYNNLVSDM RSLAIIAELN VPVVFDATHS 200
    VQQPGGLGGS TGGERKYVEL LAKAATAVGI AGMYMEVHQD PDNAPSDGPC 250
    MIKLDNLESI LIKLKKYDKI TKEK 274
    Length:274
    Mass (Da):29,971
    Last modified:July 5, 2005 - v1
    Checksum:i103EA00679A60975
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60964.1.
    RefSeqiYP_246129.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY60964; AAY60964; RF_0113.
    GeneIDi3401082.
    KEGGirfe:RF_0113.
    PATRICi17890576. VBIRicFel64634_0131.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60964.1 .
    RefSeqi YP_246129.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UN94.
    SMRi Q4UN94. Positions 17-271.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0113.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY60964 ; AAY60964 ; RF_0113 .
    GeneIDi 3401082.
    KEGGi rfe:RF_0113.
    PATRICi 17890576. VBIRicFel64634_0131.

    Phylogenomic databases

    eggNOGi COG2877.
    HOGENOMi HOG000023021.
    KOi K01627.
    OMAi MESREHA.
    OrthoDBi EOG680X4R.

    Enzyme and pathway databases

    UniPathwayi UPA00030 .
    UPA00357 ; UER00474 .
    BioCyci RFEL315456:GKEK-117-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00056. KDO8P_synth.
    InterProi IPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view ]
    PANTHERi PTHR21057:SF2. PTHR21057:SF2. 1 hit.
    Pfami PF00793. DAHP_synth_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01362. KDO8P_synth. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiKDSA_RICFE
    AccessioniPrimary (citable) accession number: Q4UN94
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3