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Q4UN89

- RSMG_RICFE

UniProt

Q4UN89 - RSMG_RICFE

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Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei68 – 681S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei125 – 1251S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

  1. rRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-122-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
Short name:
16S rRNA m7G methyltransferaseUniRule annotation
Gene namesi
Name:rsmGUniRule annotation
Ordered Locus Names:RF_0118
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 192192Ribosomal RNA small subunit methyltransferase GPRO_0000184318Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0118.

Structurei

3D structure databases

ProteinModelPortaliQ4UN89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni112 – 1132S-adenosyl-L-methionine bindingUniRule annotation

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0357.
HOGENOMiHOG000221015.
KOiK03501.
OMAiIVEAKEM.
OrthoDBiEOG6HF639.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. gidB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UN89-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMEVPREIIE KLEIFQKLVK KWNKSINLVS DNTIHNFWQR HILDSLQLMQ
60 70 80 90 100
YIDNKEIHLV DIGSGAGFPG IVLSIAGVAK VSLIEADLRK CIFLEKASKI
110 120 130 140 150
SNNNIQIINQ RIEKVEIDCS ILTCRAFSKL NTIFNCIKNI SVQEKFLLLK
160 170 180 190
GKNYLTEIVE AKEMWLFDYL IHQSITCEEG KILEVSNLTK II
Length:192
Mass (Da):22,121
Last modified:July 5, 2005 - v1
Checksum:iF752545244E79957
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60969.1.
RefSeqiWP_011270472.1. NC_007109.1.
YP_246134.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60969; AAY60969; RF_0118.
GeneIDi3401087.
KEGGirfe:RF_0118.
PATRICi17890586. VBIRicFel64634_0136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60969.1 .
RefSeqi WP_011270472.1. NC_007109.1.
YP_246134.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UN89.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0118.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY60969 ; AAY60969 ; RF_0118 .
GeneIDi 3401087.
KEGGi rfe:RF_0118.
PATRICi 17890586. VBIRicFel64634_0136.

Phylogenomic databases

eggNOGi COG0357.
HOGENOMi HOG000221015.
KOi K03501.
OMAi IVEAKEM.
OrthoDBi EOG6HF639.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-122-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_00074. 16SrRNA_methyltr_G.
InterProi IPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
Pfami PF02527. GidB. 1 hit.
[Graphical view ]
PIRSFi PIRSF003078. GidB. 1 hit.
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00138. gidB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiRSMG_RICFE
AccessioniPrimary (citable) accession number: Q4UN89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3