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Q4UN89

- RSMG_RICFE

UniProt

Q4UN89 - RSMG_RICFE

Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    • Comment

    Functioni

    Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

    Catalytic activityi

    S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei63 – 631S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
    Binding sitei68 – 681S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
    Binding sitei125 – 1251S-adenosyl-L-methionineUniRule annotation

    GO - Molecular functioni

    1. rRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    rRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-122-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
    Alternative name(s):
    16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
    Short name:
    16S rRNA m7G methyltransferaseUniRule annotation
    Gene namesi
    Name:rsmGUniRule annotation
    Ordered Locus Names:RF_0118
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 192192Ribosomal RNA small subunit methyltransferase GPRO_0000184318Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0118.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UN89.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni112 – 1132S-adenosyl-L-methionine bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0357.
    HOGENOMiHOG000221015.
    KOiK03501.
    OMAiIVEAKEM.
    OrthoDBiEOG6HF639.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_00074. 16SrRNA_methyltr_G.
    InterProiIPR003682. rRNA_ssu_MeTfrase_G.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF02527. GidB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003078. GidB. 1 hit.
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00138. gidB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4UN89-1 [UniParc]FASTAAdd to Basket

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    MMEVPREIIE KLEIFQKLVK KWNKSINLVS DNTIHNFWQR HILDSLQLMQ    50
    YIDNKEIHLV DIGSGAGFPG IVLSIAGVAK VSLIEADLRK CIFLEKASKI 100
    SNNNIQIINQ RIEKVEIDCS ILTCRAFSKL NTIFNCIKNI SVQEKFLLLK 150
    GKNYLTEIVE AKEMWLFDYL IHQSITCEEG KILEVSNLTK II 192
    Length:192
    Mass (Da):22,121
    Last modified:July 5, 2005 - v1
    Checksum:iF752545244E79957
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60969.1.
    RefSeqiYP_246134.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY60969; AAY60969; RF_0118.
    GeneIDi3401087.
    KEGGirfe:RF_0118.
    PATRICi17890586. VBIRicFel64634_0136.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY60969.1 .
    RefSeqi YP_246134.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UN89.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0118.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY60969 ; AAY60969 ; RF_0118 .
    GeneIDi 3401087.
    KEGGi rfe:RF_0118.
    PATRICi 17890586. VBIRicFel64634_0136.

    Phylogenomic databases

    eggNOGi COG0357.
    HOGENOMi HOG000221015.
    KOi K03501.
    OMAi IVEAKEM.
    OrthoDBi EOG6HF639.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-122-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_00074. 16SrRNA_methyltr_G.
    InterProi IPR003682. rRNA_ssu_MeTfrase_G.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF02527. GidB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003078. GidB. 1 hit.
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00138. gidB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiRSMG_RICFE
    AccessioniPrimary (citable) accession number: Q4UN89
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3