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Q4UN89 (RSMG_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase G

EC=2.1.1.170
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase
Gene names
Name:rsmG
Ordered Locus Names:RF_0118
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074

Catalytic activity

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00074.

Sequence similarities

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionrRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 192192Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074
PRO_0000184318

Regions

Region112 – 1132S-adenosyl-L-methionine binding By similarity

Sites

Binding site631S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site681S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site1251S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UN89 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: F752545244E79957

FASTA19222,121
        10         20         30         40         50         60 
MMEVPREIIE KLEIFQKLVK KWNKSINLVS DNTIHNFWQR HILDSLQLMQ YIDNKEIHLV 

        70         80         90        100        110        120 
DIGSGAGFPG IVLSIAGVAK VSLIEADLRK CIFLEKASKI SNNNIQIINQ RIEKVEIDCS 

       130        140        150        160        170        180 
ILTCRAFSKL NTIFNCIKNI SVQEKFLLLK GKNYLTEIVE AKEMWLFDYL IHQSITCEEG 

       190 
KILEVSNLTK II 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY60969.1.
RefSeqYP_246134.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UN89.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0118.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY60969; AAY60969; RF_0118.
GeneID3401087.
KEGGrfe:RF_0118.
PATRIC17890586. VBIRicFel64634_0136.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0357.
HOGENOMHOG000221015.
KOK03501.
OMAVESNARK.
OrthoDBEOG6HF639.
ProtClustDBPRK00107.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-122-MONOMER.

Family and domain databases

HAMAPMF_00074. 16SrRNA_methyltr_G.
InterProIPR003682. rRNA_ssu_MeTfrase_G.
[Graphical view]
PfamPF02527. GidB. 1 hit.
[Graphical view]
PIRSFPIRSF003078. GidB. 1 hit.
TIGRFAMsTIGR00138. gidB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMG_RICFE
AccessionPrimary (citable) accession number: Q4UN89
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 5, 2005
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names