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Q4UN76

- YIDC_RICFE

UniProt

Q4UN76 - YIDC_RICFE

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Protein
Membrane protein insertase YidC
Gene
yidC, RF_0131
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins By similarity.UniRule annotation

GO - Biological processi

  1. protein insertion into membrane Source: InterPro
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-135-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidC
Alternative name(s):
Foldase YidC
Membrane integrase YidC
Membrane protein YidC
Gene namesi
Name:yidC
Ordered Locus Names:RF_0131
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521Helical; Reviewed prediction
Add
BLAST
Transmembranei334 – 35421Helical; Reviewed prediction
Add
BLAST
Transmembranei357 – 37721Helical; Reviewed prediction
Add
BLAST
Transmembranei431 – 45121Helical; Reviewed prediction
Add
BLAST
Transmembranei476 – 49621Helical; Reviewed prediction
Add
BLAST
Transmembranei522 – 54221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 560560Membrane protein insertase YidCUniRule annotation
PRO_0000272371Add
BLAST

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.

Protein-protein interaction databases

STRINGi315456.RF_0131.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0706.
HOGENOMiHOG000101821.
KOiK03217.
OMAiFVTIEMR.
OrthoDBiEOG6X6RF2.

Family and domain databases

HAMAPiMF_01810. YidC_type1.
InterProiIPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UN76-1 [UniParc]FASTAAdd to Basket

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MNNNIINLIA AIILSLSIIF GWQYFVVKPE QKKQQQQIAV QKAENLKKQQ    50
LKALVEPATD IVVQEESGVQ RIKIESESLT GSISLKGLRF DDLILKKYKQ 100
DLSNNSPEVR LFSPANTENA YFAEIGLVSN LSSVKLPNND TIWNSDSEIL 150
SPEKPVNLFW VNEDGVKFLV TITVDENYLF TIEQTIVNNS DKELPIQSYG 200
LINRKYTAVE KAVNILHQGP IGCIDENLKE YSYDDIKDKK SEKFAASKVD 250
WIGITDKYWL SSLIPDKSSN YSSNFNYALK QGTERYQVDF ISPVQIIKPG 300
ENFSIKSRIF AGAKKVDLLD KYEKQYDIKL FDRAIDFGWF YIITKPVFYA 350
MNFFYGYVGN FGVSILIVTV IIKLLMFTLA NKSYRSMKKM KNLQPEIDRI 400
KNLYSDDKAR LNQEIMALYK KEKVNPVAGC LPILVQIPLF FSIYKVLYVT 450
IEMRQVPFYG WIKDLSAPDP TTIFNLFGLL PFSPPSFLMI GAWPILMAIT 500
MFLQQKMSPE PADPMQAQVM KFMPLIFLFM FSSFPVGLLI YWSWNNILSI 550
IQQYYINKFN 560
Length:560
Mass (Da):64,462
Last modified:July 5, 2005 - v1
Checksum:iF19BA53348557CBB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60982.1.
RefSeqiYP_246147.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60982; AAY60982; RF_0131.
GeneIDi3400842.
KEGGirfe:RF_0131.
PATRICi17890614. VBIRicFel64634_0150.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60982.1 .
RefSeqi YP_246147.1. NC_007109.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0131.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY60982 ; AAY60982 ; RF_0131 .
GeneIDi 3400842.
KEGGi rfe:RF_0131.
PATRICi 17890614. VBIRicFel64634_0150.

Phylogenomic databases

eggNOGi COG0706.
HOGENOMi HOG000101821.
KOi K03217.
OMAi FVTIEMR.
OrthoDBi EOG6X6RF2.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-135-MONOMER.

Family and domain databases

HAMAPi MF_01810. YidC_type1.
InterProi IPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view ]
PANTHERi PTHR12428. PTHR12428. 1 hit.
Pfami PF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view ]
PRINTSi PR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsi TIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiYIDC_RICFE
AccessioniPrimary (citable) accession number: Q4UN76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi