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Q4UN76

- YIDC_RICFE

UniProt

Q4UN76 - YIDC_RICFE

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Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.UniRule annotation

GO - Biological processi

  1. protein insertion into membrane Source: InterPro
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-135-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidCUniRule annotation
Alternative name(s):
Foldase YidCUniRule annotation
Membrane integrase YidCUniRule annotation
Membrane protein YidCUniRule annotation
Gene namesi
Name:yidCUniRule annotation
Ordered Locus Names:RF_0131
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 560560Membrane protein insertase YidCPRO_0000272371Add
BLAST

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.UniRule annotation

Protein-protein interaction databases

STRINGi315456.RF_0131.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521HelicalUniRule annotationAdd
BLAST
Transmembranei334 – 35421HelicalUniRule annotationAdd
BLAST
Transmembranei357 – 37721HelicalUniRule annotationAdd
BLAST
Transmembranei431 – 45121HelicalUniRule annotationAdd
BLAST
Transmembranei476 – 49621HelicalUniRule annotationAdd
BLAST
Transmembranei522 – 54221HelicalUniRule annotationAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0706.
HOGENOMiHOG000101821.
KOiK03217.
OMAiFVTIEMR.
OrthoDBiEOG6X6RF2.

Family and domain databases

HAMAPiMF_01810. YidC_type1.
InterProiIPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UN76 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNNIINLIA AIILSLSIIF GWQYFVVKPE QKKQQQQIAV QKAENLKKQQ
60 70 80 90 100
LKALVEPATD IVVQEESGVQ RIKIESESLT GSISLKGLRF DDLILKKYKQ
110 120 130 140 150
DLSNNSPEVR LFSPANTENA YFAEIGLVSN LSSVKLPNND TIWNSDSEIL
160 170 180 190 200
SPEKPVNLFW VNEDGVKFLV TITVDENYLF TIEQTIVNNS DKELPIQSYG
210 220 230 240 250
LINRKYTAVE KAVNILHQGP IGCIDENLKE YSYDDIKDKK SEKFAASKVD
260 270 280 290 300
WIGITDKYWL SSLIPDKSSN YSSNFNYALK QGTERYQVDF ISPVQIIKPG
310 320 330 340 350
ENFSIKSRIF AGAKKVDLLD KYEKQYDIKL FDRAIDFGWF YIITKPVFYA
360 370 380 390 400
MNFFYGYVGN FGVSILIVTV IIKLLMFTLA NKSYRSMKKM KNLQPEIDRI
410 420 430 440 450
KNLYSDDKAR LNQEIMALYK KEKVNPVAGC LPILVQIPLF FSIYKVLYVT
460 470 480 490 500
IEMRQVPFYG WIKDLSAPDP TTIFNLFGLL PFSPPSFLMI GAWPILMAIT
510 520 530 540 550
MFLQQKMSPE PADPMQAQVM KFMPLIFLFM FSSFPVGLLI YWSWNNILSI
560
IQQYYINKFN
Length:560
Mass (Da):64,462
Last modified:July 5, 2005 - v1
Checksum:iF19BA53348557CBB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60982.1.
RefSeqiWP_011270485.1. NC_007109.1.
YP_246147.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60982; AAY60982; RF_0131.
GeneIDi3400842.
KEGGirfe:RF_0131.
PATRICi17890614. VBIRicFel64634_0150.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY60982.1 .
RefSeqi WP_011270485.1. NC_007109.1.
YP_246147.1. NC_007109.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0131.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY60982 ; AAY60982 ; RF_0131 .
GeneIDi 3400842.
KEGGi rfe:RF_0131.
PATRICi 17890614. VBIRicFel64634_0150.

Phylogenomic databases

eggNOGi COG0706.
HOGENOMi HOG000101821.
KOi K03217.
OMAi FVTIEMR.
OrthoDBi EOG6X6RF2.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-135-MONOMER.

Family and domain databases

HAMAPi MF_01810. YidC_type1.
InterProi IPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view ]
PANTHERi PTHR12428. PTHR12428. 1 hit.
Pfami PF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view ]
PRINTSi PR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsi TIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiYIDC_RICFE
AccessioniPrimary (citable) accession number: Q4UN76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3