Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Prolipoprotein diacylglyceryl transferase

Gene

lgt

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. lipoprotein biosynthetic process Source: UniProtKB-HAMAP
  2. protein lipoylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-137-MONOMER.
UniPathwayiUPA00664.

Names & Taxonomyi

Protein namesi
Recommended name:
Prolipoprotein diacylglyceryl transferaseUniRule annotation (EC:2.4.99.-UniRule annotation)
Gene namesi
Name:lgtUniRule annotation
Ordered Locus Names:RF_0133
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalUniRule annotationAdd
BLAST
Transmembranei55 – 7521HelicalUniRule annotationAdd
BLAST
Transmembranei92 – 11221HelicalUniRule annotationAdd
BLAST
Transmembranei117 – 13721HelicalUniRule annotationAdd
BLAST
Transmembranei172 – 19221HelicalUniRule annotationAdd
BLAST
Transmembranei201 – 22121HelicalUniRule annotationAdd
BLAST
Transmembranei228 – 24821HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Prolipoprotein diacylglyceryl transferasePRO_0000277926Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0133.

Family & Domainsi

Sequence similaritiesi

Belongs to the Lgt family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0682.
HOGENOMiHOG000098666.
KOiK13292.
OMAiHWYGLAY.
OrthoDBiEOG6MH5CQ.

Family and domain databases

HAMAPiMF_01147. Lgt.
InterProiIPR001640. Prolipoprot_diAcglycer_Trfase.
[Graphical view]
PfamiPF01790. LGT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00544. lgt. 1 hit.
PROSITEiPS01311. LGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UN74-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFPNINPII FSIGPLAVSW YSLSYVVGIL LGWFYANKII EKFKPQITKK
60 70 80 90 100
NLEDFITYAV IGIIVGGRLG FVLLYNPSRY FSNPIDILKT YEGGMSFHGG
110 120 130 140 150
ALGVIIAAYL FCRKYKINFL SLTDIIAPVV PIGLFLGRIA NFINGELYGR
160 170 180 190 200
ITNSSFGMIF PNSDLMPRHP SQLYEAFFEG LVLFCILAYA TFKHKTLKKY
210 220 230 240 250
GLNSGIFLIF YALFRIAIEI FREPDIQIGF ILDSLTMGQI LSVPMLLLGS

YLICQSNPK
Length:259
Mass (Da):29,153
Last modified:July 5, 2005 - v1
Checksum:i18FB9DF76303CABE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY60984.1.
RefSeqiWP_011270487.1. NC_007109.1.
YP_246149.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY60984; AAY60984; RF_0133.
GeneIDi3401217.
KEGGirfe:RF_0133.
PATRICi17890618. VBIRicFel64634_0152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY60984.1.
RefSeqiWP_011270487.1. NC_007109.1.
YP_246149.1. NC_007109.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0133.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY60984; AAY60984; RF_0133.
GeneIDi3401217.
KEGGirfe:RF_0133.
PATRICi17890618. VBIRicFel64634_0152.

Phylogenomic databases

eggNOGiCOG0682.
HOGENOMiHOG000098666.
KOiK13292.
OMAiHWYGLAY.
OrthoDBiEOG6MH5CQ.

Enzyme and pathway databases

UniPathwayiUPA00664.
BioCyciRFEL315456:GKEK-137-MONOMER.

Family and domain databases

HAMAPiMF_01147. Lgt.
InterProiIPR001640. Prolipoprot_diAcglycer_Trfase.
[Graphical view]
PfamiPF01790. LGT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00544. lgt. 1 hit.
PROSITEiPS01311. LGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiLGT_RICFE
AccessioniPrimary (citable) accession number: Q4UN74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: July 5, 2005
Last modified: January 7, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.