Q4UN74 (LGT_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Prolipoprotein diacylglyceryl transferase
EC=2.4.99.-

Gene names

Name:	lgt
Ordered Locus Names:	RF_0133

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia felis

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins By similarity. HAMAP-Rule MF_01147
Pathway	Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). HAMAP-Rule MF_01147
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01147.
Sequence similarities	Belongs to the lgt family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lipoprotein biosynthetic process Inferred from electronic annotation. Source: HAMAP protein lipoylation Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 259	259	Prolipoprotein diacylglyceryl transferase HAMAP-Rule MF_01147		PRO_0000277926
Regions
	Transmembrane	9 – 29	21	Helical; Potential
	Transmembrane	55 – 75	21	Helical; Potential
	Transmembrane	92 – 112	21	Helical; Potential
	Transmembrane	117 – 137	21	Helical; Potential
	Transmembrane	172 – 192	21	Helical; Potential
	Transmembrane	201 – 221	21	Helical; Potential
	Transmembrane	228 – 248	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q4UN74 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 18FB9DF76303CABE	FASTA	259	29,153
	10 20 30 40 50 60 MTFPNINPII FSIGPLAVSW YSLSYVVGIL LGWFYANKII EKFKPQITKK NLEDFITYAV 70 80 90 100 110 120 IGIIVGGRLG FVLLYNPSRY FSNPIDILKT YEGGMSFHGG ALGVIIAAYL FCRKYKINFL 130 140 150 160 170 180 SLTDIIAPVV PIGLFLGRIA NFINGELYGR ITNSSFGMIF PNSDLMPRHP SQLYEAFFEG 190 200 210 220 230 240 LVLFCILAYA TFKHKTLKKY GLNSGIFLIF YALFRIAIEI FREPDIQIGF ILDSLTMGQI 250 LSVPMLLLGS YLICQSNPK

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY60984.1.
RefSeq	YP_246149.1. NC_007109.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	315456.RF_0133.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAY60984; AAY60984; RF_0133.
GeneID	3401217.
KEGG	rfe:RF_0133.
PATRIC	17890618. VBIRicFel64634_0152.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0682.
HOGENOM	HOG000098666.
KO	K13292.
OMA	ANFINCE.
ProtClustDB	PRK00052.
Enzyme and pathway databases
UniPathway	UPA00664.
Family and domain databases
HAMAP	MF_01147. Lgt.
InterPro	IPR001640. Prolipoprot_diAcglycer_Trfase. [Graphical view]
Pfam	PF01790. LGT. 1 hit. [Graphical view]
TIGRFAMs	TIGR00544. lgt. 1 hit.
PROSITE	PS01311. LGT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LGT_RICFE

Accession

Primary (citable) accession number: Q4UN74

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program