Q4UN61 (GCP_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	RF_0146

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303524

Sequences

	Sequence		Length	Mass (Da)
	Q4UN61 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 539FD6FA41886E00	FASTA	389	42,643
	10 20 30 40 50 60 MIKILGIESS CDDTAVSIIT ENREILSNII ISQNTEHAVF GGVVPEIAAR SHLSNLDKAL 70 80 90 100 110 120 KNVLKESNTK LTEISAIAAT SGPGLIGGVI VGSMFARSLS SAFKKPFIAI NHLEGHALTA 130 140 150 160 170 180 RLTDNIPYPY LLLLASGGHC QFVAVLGLGK YKILGSTIDD AIGEAFDKVA KMLNLAFPGG 190 200 210 220 230 240 PEIEKRAKLG DPHKYKFPKP IINSGNCNMS FSGLKTAVRT LIMSLKELND AVINDIAASF 250 260 270 280 290 300 QFTIGEILSS KVQDAIIAYE RVVNDYYENI DYTTQLNLKS FRQDEFKEEP AEHTKVREHR 310 320 330 340 350 360 LYPQNSLGSS FLNDAIVIAG GVAANKYLQE ILSNCAKTYG YQLIYPPIRL CTDNAAMIAY 370 380 AGLERYNNKL FTPLNFCPKA RWSLEDISK

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY60997.1.
RefSeq	YP_246162.1. NC_007109.1.
3D structure databases
ProteinModelPortal	Q4UN61.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3400647.
GenomeReviews	Gene locus RF_0146 in contig CP000053_GR.
KEGG	rfe:RF_0146.
NMPDR	fig|315456.3.peg.665.
PATRIC	17890646. VBIRicFel64634_0166.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	KDCNFSY.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0146-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. IPR022437. RPE3. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 2 hits. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. TIGR03775. RPE3. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_RICFE

Accession

Primary (citable) accession number: Q4UN61

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 5, 2005
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program