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Q4UN54

- Q4UN54_RICFE

UniProt

Q4UN54 - Q4UN54_RICFE

Protein
Submitted name:

Acetoacetyl-CoA reductase

Gene

phbB

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: UniProtKB-EC
    2. acetoacetyl-CoA reductase activity Source: InterPro

    GO - Biological processi

    1. poly-hydroxybutyrate biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-157-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Acetoacetyl-CoA reductaseImported (EC:1.1.1.100Imported)
    Gene namesi
    Name:phbBImported
    Ordered Locus Names:RF_0153Imported
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)Imported
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0153.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4KMSX-ray2.00A/B1-241[»]
    ProteinModelPortaliQ4UN54.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

    Phylogenomic databases

    KOiK00023.
    OMAiHINGATI.
    OrthoDBiEOG6N3CR8.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR011283. Acetoacetyl-CoA_reductase.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view]
    PfamiPF00106. adh_short. 1 hit.
    [Graphical view]
    PRINTSiPR00081. GDHRDH.
    PR00080. SDRFAMILY.
    TIGRFAMsiTIGR01829. AcAcCoA_reduct. 1 hit.
    PROSITEiPS00061. ADH_SHORT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UN54-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEIAIVTGG TRGIGKATAL ELKNKGLTVV ANFFSNYDAA KEMEEKYGIK    50
    TKCWNVADFE ECRQAVKEIE EEFKKPVSIL VNNAGITKDK MLHRMSHQDW 100
    NDVINVNLNS CFNMSSSVME QMRNQDYGRI VNISSINAQA GQVGQTNYSA 150
    AKAGIIGFTK ALARETASKN ITVNCIAPGY IATEMVGAVP EDVLAKIINS 200
    IPKKRLGQPE EIARAVAFLV DENAGFITGE TISINGGHNM I 241
    Length:241
    Mass (Da):26,252
    Last modified:July 5, 2005 - v1
    Checksum:iFB09A2EDA99C0651
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61004.1.
    RefSeqiWP_011270506.1. NC_007109.1.
    YP_246169.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61004; AAY61004; RF_0153.
    GeneIDi3401047.
    KEGGirfe:RF_0153.
    PATRICi17890660. VBIRicFel64634_0173.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61004.1 .
    RefSeqi WP_011270506.1. NC_007109.1.
    YP_246169.1. NC_007109.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4KMS X-ray 2.00 A/B 1-241 [» ]
    ProteinModelPortali Q4UN54.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0153.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61004 ; AAY61004 ; RF_0153 .
    GeneIDi 3401047.
    KEGGi rfe:RF_0153.
    PATRICi 17890660. VBIRicFel64634_0173.

    Phylogenomic databases

    KOi K00023.
    OMAi HINGATI.
    OrthoDBi EOG6N3CR8.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-157-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR011283. Acetoacetyl-CoA_reductase.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view ]
    Pfami PF00106. adh_short. 1 hit.
    [Graphical view ]
    PRINTSi PR00081. GDHRDH.
    PR00080. SDRFAMILY.
    TIGRFAMsi TIGR01829. AcAcCoA_reduct. 1 hit.
    PROSITEi PS00061. ADH_SHORT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2Imported.
    2. "Crystal structure of Acetoacetyl-CoA reductase from Rickettsia felis."
      Seattle Structural Genomics Center for Infectious Disease (SSGCID)
      Abendroth J., Sankaran B., Davies D.R., Edwards T.E., Staker B.L.
      Submitted (MAY-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).

    Entry informationi

    Entry nameiQ4UN54_RICFE
    AccessioniPrimary (citable) accession number: Q4UN54
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2005
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3