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Q4UN54

- Q4UN54_RICFE

UniProt

Q4UN54 - Q4UN54_RICFE

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Protein
Submitted name: Acetoacetyl-CoA reductase
Gene
phbB, RF_0153
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: UniProtKB-EC
  2. acetoacetyl-CoA reductase activity Source: InterPro

GO - Biological processi

  1. poly-hydroxybutyrate biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-157-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Acetoacetyl-CoA reductaseImported (EC:1.1.1.100Imported)
Gene namesi
Name:phbBImported
Ordered Locus Names:RF_0153Imported
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)Imported
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0153.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4KMSX-ray2.00A/B1-241[»]
ProteinModelPortaliQ4UN54.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00023.
OMAiHINGATI.
OrthoDBiEOG6N3CR8.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011283. Acetoacetyl-CoA_reductase.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsiTIGR01829. AcAcCoA_reduct. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UN54-1 [UniParc]FASTAAdd to Basket

« Hide

MSEIAIVTGG TRGIGKATAL ELKNKGLTVV ANFFSNYDAA KEMEEKYGIK    50
TKCWNVADFE ECRQAVKEIE EEFKKPVSIL VNNAGITKDK MLHRMSHQDW 100
NDVINVNLNS CFNMSSSVME QMRNQDYGRI VNISSINAQA GQVGQTNYSA 150
AKAGIIGFTK ALARETASKN ITVNCIAPGY IATEMVGAVP EDVLAKIINS 200
IPKKRLGQPE EIARAVAFLV DENAGFITGE TISINGGHNM I 241
Length:241
Mass (Da):26,252
Last modified:July 5, 2005 - v1
Checksum:iFB09A2EDA99C0651
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61004.1.
RefSeqiWP_011270506.1. NC_007109.1.
YP_246169.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61004; AAY61004; RF_0153.
GeneIDi3401047.
KEGGirfe:RF_0153.
PATRICi17890660. VBIRicFel64634_0173.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61004.1 .
RefSeqi WP_011270506.1. NC_007109.1.
YP_246169.1. NC_007109.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4KMS X-ray 2.00 A/B 1-241 [» ]
ProteinModelPortali Q4UN54.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0153.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61004 ; AAY61004 ; RF_0153 .
GeneIDi 3401047.
KEGGi rfe:RF_0153.
PATRICi 17890660. VBIRicFel64634_0173.

Phylogenomic databases

KOi K00023.
OMAi HINGATI.
OrthoDBi EOG6N3CR8.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-157-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR011283. Acetoacetyl-CoA_reductase.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsi TIGR01829. AcAcCoA_reduct. 1 hit.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.E., Parinello H., Claverie J.M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.
  2. "Crystal structure of Acetoacetyl-CoA reductase from Rickettsia felis."
    Seattle Structural Genomics Center for Infectious Disease (SSGCID)
    Abendroth J., Sankaran B., Davies D.R., Edwards T.E., Staker B.L.
    Submitted (MAY-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).

Entry informationi

Entry nameiQ4UN54_RICFE
AccessioniPrimary (citable) accession number: Q4UN54
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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