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Q4UN46

- TLCE_RICFE

UniProt

Q4UN46 - TLCE_RICFE

Protein

ADP,ATP carrier protein 5

Gene

tlcE

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.By similarity

    GO - Molecular functioni

    1. ATP:ADP antiporter activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-165-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ADP,ATP carrier protein 5
    Alternative name(s):
    ADP/ATP translocase 5
    Gene namesi
    Name:tlcE
    Synonyms:tlc5
    Ordered Locus Names:RF_0161
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 499499ADP,ATP carrier protein 5PRO_0000286479Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0161.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei25 – 4521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei61 – 8121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei93 – 11321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei148 – 16821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei183 – 20321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei223 – 24321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei286 – 30621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei327 – 34721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei356 – 37621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei380 – 40021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei468 – 48821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADP/ATP translocase tlc family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3202.
    HOGENOMiHOG000238123.
    KOiK03301.
    OMAiMQHEREA.
    OrthoDBiEOG6BCSND.

    Family and domain databases

    InterProiIPR004667. ADP_ATP_car.
    [Graphical view]
    PfamiPF03219. TLC. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00769. AAA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4UN46-1 [UniParc]FASTAAdd to Basket

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    MLSTSSRSFK SKFRAAFWPV HNYELGKFIP MSALMFCILF NQNILRILKD    50
    SILISEISAE IAGFAKVYCV TPAAALFVII YAKMINRFTF EKIFYYLSAF 100
    FISFFVLFAF VIYPNIHVFH VHPDNLADWM ERYPHFKWYI SLVGNWGYIV 150
    YYSLAELWPN IFYVLLFWQF ANELTTTEEA KRFYTFFSLF GNSSLILVGF 200
    LMMNLSSEDT IIKKFMSISD SKITLVQVST TIVAIVAIVC CVLVRFISKN 250
    VFTNPLFYAK AKSGRSTSER MGLIKSFKYI AKSKYLWLLL ICSAAFGFAI 300
    NLVEAVWKAK IKELYPTVNT YAEFNSLYIL WTGVAIMVMT IIGNNVMRMH 350
    NWFVAAVISP VIIMVTGILF FVLIVFDQQI LSLFDGAILM SPLALAVSIG 400
    GIQNILAKGT KYSIWDTSRE MLYIPLDDEL KTKGKAAVDV ISAKVGKSSS 450
    GLVQSIIFTL VPTATFTSIS PILMVVFTFV CLAWIYAVRK IYFEYQKIA 499
    Length:499
    Mass (Da):56,856
    Last modified:July 5, 2005 - v1
    Checksum:i07701BA22105E10F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61012.1.
    RefSeqiYP_246177.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61012; AAY61012; RF_0161.
    GeneIDi3401055.
    KEGGirfe:RF_0161.
    PATRICi17890678. VBIRicFel64634_0182.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61012.1 .
    RefSeqi YP_246177.1. NC_007109.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0161.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61012 ; AAY61012 ; RF_0161 .
    GeneIDi 3401055.
    KEGGi rfe:RF_0161.
    PATRICi 17890678. VBIRicFel64634_0182.

    Phylogenomic databases

    eggNOGi COG3202.
    HOGENOMi HOG000238123.
    KOi K03301.
    OMAi MQHEREA.
    OrthoDBi EOG6BCSND.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-165-MONOMER.

    Family and domain databases

    InterProi IPR004667. ADP_ATP_car.
    [Graphical view ]
    Pfami PF03219. TLC. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00769. AAA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiTLCE_RICFE
    AccessioniPrimary (citable) accession number: Q4UN46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3