ID   Q4UMW3_RICFE            Unreviewed;       478 AA.
AC   Q4UMW3;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   SubName: Full=2-polyprenylphenol 6-hydroxylase {ECO:0000313|EMBL:AAY61095.1};
DE            EC=1.14.13.- {ECO:0000313|EMBL:AAY61095.1};
GN   Name=ubiB {ECO:0000313|EMBL:AAY61095.1};
GN   OrderedLocusNames=RF_0244 {ECO:0000313|EMBL:AAY61095.1};
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456 {ECO:0000313|EMBL:AAY61095.1, ECO:0000313|Proteomes:UP000008548};
RN   [1] {ECO:0000313|EMBL:AAY61095.1, ECO:0000313|Proteomes:UP000008548}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2 {ECO:0000313|Proteomes:UP000008548};
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.E.,
RA   Parinello H., Claverie J.M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis [regulation].
CC       {ECO:0000256|ARBA:ARBA00005020}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC       kinase family. {ECO:0000256|ARBA:ARBA00009670}.
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DR   EMBL; CP000053; AAY61095.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4UMW3; -.
DR   STRING; 315456.RF_0244; -.
DR   KEGG; rfe:RF_0244; -.
DR   eggNOG; COG0661; Bacteria.
DR   HOGENOM; CLU_006533_0_0_5; -.
DR   OrthoDB; 9795390at2; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd13972; UbiB; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR004147; ABC1_dom.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR010232; UbiB.
DR   InterPro; IPR045308; UbiB_bact.
DR   NCBIfam; TIGR01982; UbiB; 1.
DR   PANTHER; PTHR10566; CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED; 1.
DR   PANTHER; PTHR10566:SF129; PROTEIN KINASE UBIB-RELATED; 1.
DR   Pfam; PF03109; ABC1; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Oxidoreductase {ECO:0000313|EMBL:AAY61095.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Ubiquinone biosynthesis {ECO:0000256|ARBA:ARBA00022688}.
FT   DOMAIN          146..449
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   478 AA;  54310 MW;  72617A11C3BC7AC6 CRC64;
     MISNFFNLIR IFRIISKKRI LIDSRSPKYF RFIGYILALF SAPLSLFKKP HEDYGKRLID
     CLSELGPIYI KFGQTLSTRP DLVGAEIAGY LRLLQDKLPP FDGGVARKLI ASLRGDIYVD
     EAISASKQKI ATHSTNAHND ALPFLHFDDR PVAAASISQV HKAQLATGEY VAVKILRPGI
     HKKYNRDIKL LYFLAKIISK FSKAKRLKPI KVVDKFHETM RFELDLRLEA AASSELMDNM
     RNDINVINPK IYWDLTSENI LTTEWLEGTS IYDTSLLKEM GLEPAKIAQN FAVMFFNQAY
     RDGFFHADLH AGNILVNKQG KIILLDFGIM GRLKEKDRLA VAESLFGFLN RDYKLVAKVH
     LRAGYIPSNT DLDLFAQSCR AVTEPILGTP TKNISIGKLL AHLFKITEDF GMEVQPELLL
     LQKTLIMVEG IGRQLDGNVN MWQLAEPWIK KWAVKNLSSE AKLLRLVKHY LDSLEDIV
//