Q4UMU2 (AMPG2_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative transporter AmpG 2

Gene names

Name:	ampG2
Ordered Locus Names:	RF_0265

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia felis

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the major facilitator superfamily.
Sequence caution	The sequence AAY61116.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 408	408	Putative transporter AmpG 2		PRO_0000281096
Regions
	Transmembrane	10 – 30	21	Helical; Potential
	Transmembrane	49 – 69	21	Helical; Potential
	Transmembrane	84 – 104	21	Helical; Potential
	Transmembrane	109 – 129	21	Helical; Potential
	Transmembrane	154 – 174	21	Helical; Potential
	Transmembrane	177 – 197	21	Helical; Potential
	Transmembrane	224 – 244	21	Helical; Potential
	Transmembrane	261 – 281	21	Helical; Potential
	Transmembrane	294 – 311	18	Helical; Potential
	Transmembrane	315 – 337	23	Helical; Potential
	Transmembrane	353 – 373	21	Helical; Potential
	Transmembrane	378 – 398	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q4UMU2 [UniParc]. Last modified March 20, 2007. Version 2. Checksum: DEFDECDAA939D308	FASTA	408	46,979
	10 20 30 40 50 60 MNFNFSRFQY ISNIFFILII SFPGGLIYLL TGSTLSFWLR ESGFDKITIG LFSLVNFIHI 70 80 90 100 110 120 FKFLWGPLLE KVSFAPLSKR GYKYCLIIAL VSCICCVYIL TNFNPNTHFI PFALCLVAVA 130 140 150 160 170 180 FFSSIYDMLL QSSQMLLITN KNWGISEAAC TTGFRIGILI AGSGALYLST IISWQDVYRS 190 200 210 220 230 240 MAILCIPSLL LIIIYPLKFK DKTIINDFDR FWYAFYDFIK KPKWLIIVSF MLLYRLQDNF 250 260 270 280 290 300 LSIMPNMFYL DIGYTKKDLA LGYKAFGMCA AILGGFIGGF LCRKYEYFYL LKRALIYHAL 310 320 330 340 350 360 SSLSFLFLYF YNRDITSLYI AVFFQEFTKG LTMSPFFSYQ LRCCSSKYCI TQIALITSIA 370 380 390 400 YISTILFGSI SGYAATYLGW TYFFLVAGFC FIPAYILIKY LPPYVIPS

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY61116.1. Different initiation.
RefSeq	YP_246281.1. NC_007109.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	315456.RF_0265.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAY61116; AAY61116; RF_0265.
GeneID	3400672.
KEGG	rfe:RF_0265.
PATRIC	17890934. VBIRicFel64634_0306.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0477.
HOGENOM	HOG000010880.
OMA	YHALSSI.
ProtClustDB	CLSK871022.
Family and domain databases
InterPro	IPR011701. MFS. IPR016196. MFS_dom_general_subst_transpt. [Graphical view]
Pfam	PF07690. MFS_1. 1 hit. [Graphical view]
SUPFAM	SSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITE	PS50850. MFS. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AMPG2_RICFE

Accession

Primary (citable) accession number: Q4UMU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	May 1, 2013
This is version 49 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program